PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Zmw_sc01732.1.g00050.1
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Zoysieae; Zoysiinae; Zoysia
Family NAC
Protein Properties Length: 238aa    MW: 26963.4 Da    PI: 6.5856
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
                             NAM   1 lppGfrFhPtdeelvveyLkkkvegkk......leleev.ikev.diykvePwdLpkkvkaeekewyfFskrdkkyatg 71 
                                     lp+G++F+P+d +l+ e+L+kk+          ++++ + +++  +i++++P++Lp  +k++ + ++fF++  k+y  g   8 LPAGVKFDPSDLQLL-EHLEKKIGLGGsephvfIDEFIAtVENDeGICYSHPENLP-GMKKDGNVVHFFHRVLKAYGCG 84 
                                     799************.99****976665666553332332332236**********.677888999************* PP

                             NAM  72 krknra..........tksgyWkatgkdkevlskkgelvglkktLvfykg..rapkgektdWvmheyrl 128
                                     +rk+r            ++ +W++tg++k++++ +g ++g kk+Lv+yk   ++ ++e++ Wvmh+y+l  85 QRKRRRvitcsdhavsDEHVRWHKTGRSKAIYD-NGVTKGWKKILVLYKTpqSSGRPERAPWVMHQYHL 152
                                     *****6588888887666899************.99************86224555679********98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019416.41E-342171IPR003441NAC domain
PROSITE profilePS5100528.0058171IPR003441NAC domain
PfamPF023655.2E-129152IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 238 aa     Download sequence    Send to blast
Nucleic Localization Signal ? help Back to Top
No. Start End Sequence
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor regulating the transcriptional activation response to gamma irradiation (PubMed:19549833). Required for stem-cell death induced by UVB or by gamma irradiation (PubMed:20634150). Not required for ATM activation, but participates in pathways governed by both ATM and ATR sensor kinases (PubMed:19549833). Involved in DNA damage response (DDR) system that regulates cell cycle arrest (PubMed:24399300). Functional homolog of animal p53 (PubMed:24736489). Regulates SMR5 and SMR7 transcription (PubMed:24399300). Regulates DNA repair and cytokinin signaling separately and plays a key role in controlling lateral root formation under genotoxic stress. {ECO:0000269|PubMed:19549833, ECO:0000269|PubMed:20634150, ECO:0000269|PubMed:24399300, ECO:0000305|PubMed:24736489}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not induced by zeocin or ionizing radiation treatment. {ECO:0000269|PubMed:23907539}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001149204.11e-121uncharacterized protein LOC100282826
RefseqXP_008677272.11e-121putative NAC domain transcription factor superfamily protein isoform X1
TrEMBLA0A3L6QEE71e-122A0A3L6QEE7_PANMI; NAC domain-containing protein 73-like
STRINGPavir.Aa01341.1.p1e-125(Panicum virgatum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Publications ? help Back to Top
  1. Yi D, et al.
    The Arabidopsis SIAMESE-RELATED cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species.
    Plant Cell, 2014. 26(1): p. 296-309
  2. Biever JJ,Brinkman D,Gardner G
    UV-B inhibition of hypocotyl growth in etiolated Arabidopsis thaliana seedlings is a consequence of cell cycle arrest initiated by photodimer accumulation.
    J. Exp. Bot., 2014. 65(11): p. 2949-61
  3. Hu Z,Cools T,Kalhorzadeh P,Heyman J,De Veylder L
    Deficiency of the Arabidopsis helicase RTEL1 triggers a SOG1-dependent replication checkpoint in response to DNA cross-links.
    Plant Cell, 2015. 27(1): p. 149-61
  4. Chen P,Umeda M
    DNA double-strand breaks induce the expression of flavin-containing monooxygenase and reduce root meristem size in Arabidopsis thaliana.
    Genes Cells, 2015. 20(8): p. 636-46
  5. Sjogren CA,Bolaris SC,Larsen PB
    Aluminum-Dependent Terminal Differentiation of the Arabidopsis Root Tip Is Mediated through an ATR-, ALT2-, and SOG1-Regulated Transcriptional Response.
    Plant Cell, 2015. 27(9): p. 2501-15
  6. Yoshiyama KO
    SOG1: a master regulator of the DNA damage response in plants.
    Genes Genet. Syst., 2016. 90(4): p. 209-16
  7. Weimer AK, et al.
    The plant-specific CDKB1-CYCB1 complex mediates homologous recombination repair in Arabidopsis.
    EMBO J., 2016. 35(19): p. 2068-2086
  8. Davis OM,Ogita N,Inagaki S,Takahashi N,Umeda M
    DNA damage inhibits lateral root formation by up-regulating cytokinin biosynthesis genes in Arabidopsis thaliana.
    Genes Cells, 2016. 21(11): p. 1195-1208
  9. Pedroza-GarcĂ­a JA, et al.
    Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis.
    Plant Physiol., 2017. 173(3): p. 1735-1749
  10. Horvath BM, et al.
    Arabidopsis RETINOBLASTOMA RELATED directly regulates DNA damage responses through functions beyond cell cycle control.
    EMBO J., 2017. 36(9): p. 1261-1278
  11. Sjogren CA,Larsen PB
    SUV2, which encodes an ATR-related cell cycle checkpoint and putative plant ATRIP, is required for aluminium-dependent root growth inhibition in Arabidopsis.
    Plant Cell Environ., 2017. 40(9): p. 1849-1860
  12. Yoshiyama KO,Kaminoyama K,Sakamoto T,Kimura S
    Increased Phosphorylation of Ser-Gln Sites on SUPPRESSOR OF GAMMA RESPONSE1 Strengthens the DNA Damage Response in Arabidopsis thaliana.
    Plant Cell, 2017. 29(12): p. 3255-3268
  13. Johnson RA, et al.
    SUPPRESSOR OF GAMMA RESPONSE1 Links DNA Damage Response to Organ Regeneration.
    Plant Physiol., 2018. 176(2): p. 1665-1675
  14. Ogita N, et al.
    Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis.
    Plant J., 2018. 94(3): p. 439-453
  15. Cao X, et al.
    Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots.
    Chemosphere, 2018. 201: p. 586-594