PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AC200124.3_FGP005
Common NameGRAS66
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
Family GRAS
Protein Properties Length: 111aa    MW: 12308.9 Da    PI: 4.6744
Description GRAS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AC200124.3_FGP005genomeMaizeSequenceView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1GRAS72.21e-222110205315
               GRAS 205 nlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFlerflealeyysalfdsl.eaklpreseerikvErellgreiv 295
                        n+vl+ h+ll +++  +    ++L l +s+ ++++ + e+e  +ns ++ +rf+ al+yy++ fd +  a+l+ +  +r+k E++ ++rei+
  AC200124.3_FGP005   2 NCVLAAHHLLYDETGAAV--VDFLGLARSTGATILLLGEHEDTLNSRRWEARFALALRYYATAFDVMgTAGLADAGPARAKAEEM-FAREIC 90 
                        9*******9977766666..79*********************************************888999999*********.****** PP

               GRAS 296 nvvacegaerrerhetlekW 315
                        n va e a+r+er et++ W
  AC200124.3_FGP005  91 NTVAFEAADRFERYETFAGW 110
                        *******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5098514.2951111IPR005202Transcription factor GRAS
PfamPF035143.5E-202110IPR005202Transcription factor GRAS
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
Sequence ? help Back to Top
Protein Sequence    Length: 111 aa     Download sequence    Send to blast
MNCVLAAHHL LYDETGAAVV DFLGLARSTG ATILLLGEHE DTLNSRRWEA RFALALRYYA  60
TAFDVMGTAG LADAGPARAK AEEMFAREIC NTVAFEAADR FERYETFAGW W
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Zm.342991e-101cell lignification| meristem| shoot
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasAC200124.3_FG005
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the shoot apical meristem (SAM) and elongating cells of young seedlings. Expressed in leaf joints, culms, internodes, stems, young panicles, primary roots and lateral roots. {ECO:0000269|PubMed:19220793}.
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor that acts as positivie regulator of brassinosteroid (BR) signaling (PubMed:19220793, PubMed:22685166). Functions downstream of BRI1 and GSK2 to modulate BR responses. Acts as a direct target of GSK2 kinase to mediate BR responses (PubMed:22685166). Involved in feedback inhibition of BR biosynthetic genes. Repressed by BZR1 (PubMed:19220793). {ECO:0000269|PubMed:19220793, ECO:0000269|PubMed:22685166}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAC200124.3_FGP005
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by 24-epibrassinolide. {ECO:0000269|PubMed:19220793}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKJ7282820.0KJ728282.1 Zea mays clone pUT6561 GRAS transcription factor (GRAS66) gene, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020406475.12e-48LOW QUALITY PROTEIN: protein DWARF AND LOW-TILLERING
SwissprotQ9LWU98e-36DLT_ORYSJ; Protein DWARF AND LOW-TILLERING
TrEMBLK7UFS57e-74K7UFS5_MAIZE; GRAS transcription factor (Fragment)
STRINGAC200124.3_FGP0051e-74(Zea mays)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP64043455
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G63100.12e-24GRAS family protein
Publications ? help Back to Top
  1. Tong H,Chu C
    Roles of DLT in fine modulation on brassinosteroid response in rice.
    Plant Signal Behav, 2009. 4(5): p. 438-9
    [PMID:19816111]
  2. Li W, et al.
    Identification and characterization of dwarf 62, a loss-of-function mutation in DLT/OsGRAS-32 affecting gibberellin metabolism in rice.
    Planta, 2010. 232(6): p. 1383-96
    [PMID:20830595]
  3. Tong H, et al.
    DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice.
    Plant Cell, 2012. 24(6): p. 2562-77
    [PMID:22685166]
  4. Zhang C,Bai MY,Chong K
    Brassinosteroid-mediated regulation of agronomic traits in rice.
    Plant Cell Rep., 2014. 33(5): p. 683-96
    [PMID:24667992]
  5. Yang C,Shen W,He Y,Tian Z,Li J
    OVATE Family Protein 8 Positively Mediates Brassinosteroid Signaling through Interacting with the GSK3-like Kinase in Rice.
    PLoS Genet., 2016. 12(6): p. e1006118
    [PMID:27332964]