PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_015898821.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rhamnaceae; Paliureae; Ziziphus
Family E2F/DP
Protein Properties Length: 472aa    MW: 52156.1 Da    PI: 4.8256
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_015898821.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.12.5e-27147212171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  XP_015898821.1 147 RYDSSLGLLTKKFINLIKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 212
                     6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.1E-29144214IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467855.08E-17147210IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.0E-34147212IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.4E-24149212IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440741.73E-33225329No hitNo description
PfamPF164211.4E-32228327IPR032198E2F transcription factor, CC-MB domain
CDDcd146603.43E-47228329No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 472 aa     Download sequence    Send to blast
MSGNPRAPNR PTPPPPVPSG GGQILPPLRR HLAFASTKPP FLPPDDYHRF SGDAHRAADQ  60
EPEAIVVRSP QLKRKNGIDN SEVEHGDWMS GSGYTNVINS PLNTPVSAKG GRAYNRSKTS  120
KGNRSAPQTP VSNAGSPSPL TPAGSCRYDS SLGLLTKKFI NLIKHAEDGI LDLNKAAETL  180
EVQKRRIYDI TNVLEGIGLI EKKLKNRIRW KGLDASRPGE VDGDITTLQA EVDNLSMEER  240
RLDDRIREMQ ERLRDLSEDE NNQKWLFVTE DDIKGLPCFQ NETLIAIKAP HGTTLEVPDP  300
DEAVDYPQRR YRIILRSTMG PVDVYLVSQF EEKFEEMNGV VPPASFPLAS SSGSNEHPVT  360
EVVTMDNTRK DIEPQVQNDH QMCSDINASQ EFGGGMMKIV PSDVDNDADY WLLSDAEVSI  420
TDMWRTDSGV DWNGADILHA DFGMTDVSTP RSQDPPSGIA EAPTSNVHFS PR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-23142213274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00661PBMTransfer from Pp3c1_6880Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_015898821.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015898821.10.0transcription factor E2FA isoform X1
SwissprotQ9FNY00.0E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A2P5D9W80.0A0A2P5D9W8_PARAD; E2F Family
STRINGEMJ055330.0(Prunus persica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.10.0E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]