PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_015873117.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rhamnaceae; Paliureae; Ziziphus
Family E2F/DP
Protein Properties Length: 415aa    MW: 46325.8 Da    PI: 4.4668
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_015873117.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.81.6e-2795160171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  XP_015873117.1  95 RYDSSLGLLTKKFINLIKHAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 160
                     6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.102.7E-2993162IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.2E-3595160IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.54E-1795158IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.3E-2497160IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146602.13E-47171277No hitNo description
SuperFamilySSF1440741.7E-33172277No hitNo description
PfamPF164211.9E-33176275IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 415 aa     Download sequence    Send to blast
MIASRWFEFA AISFELTLKR KSETAEYEAE SSDRMVGPVY AEVVNSPIQT PVSTKAGKTN  60
KTPRVMKCTR TGPQTPLSNV GSPSGANLTP AGPCRYDSSL GLLTKKFINL IKHAEDGILD  120
LNKAADTLEV QKRRIYDITN VLEGIGLIEK KLKNRIQWKG LDVTRPGEAE DNYASLQAEV  180
DNLSIEEHRL DDQIREMQER LRDLSEDEKN QKLLFVTEED IKGLPIFQNE TLIAIKAPHG  240
TTLEVPDPDE AVDYPQRRYR IVLRSTMGPI DVYLVSQFEE KFEEINGVEL PTSFPSSSGI  300
RDDPAAALVI ENTAHNVELQ GQDDHRTYAD PSASQDFVSG IMKIVPSDVD SDADYWLLSD  360
ADISITDMWR TEPGVEWNEL GLHEDYTMVN VSKSRPQTPP SNSTEVPSTA NHTSS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A4e-2790161274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_015873117.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024924994.10.0transcription factor E2FB-like isoform X3
RefseqXP_024926871.10.0transcription factor E2FB-like isoform X1
SwissprotQ9FV711e-148E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A314Z8V30.0A0A314Z8V3_PRUYE; Transcription factor E2FB isoform X2
STRINGEMJ094780.0(Prunus persica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.21e-150E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]