PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Vradi08g00970.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Vigna
Family E2F/DP
Protein Properties Length: 510aa    MW: 56340.5 Da    PI: 5.1988
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Vradi08g00970.1genomeSNUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.77.4e-27176241171
          E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                      r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Vradi08g00970.1 176 RYDSSLGLLTKKFINLVKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 241
                      6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.5E-29173243IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.2E-34176241IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467857.48E-17176239IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023192.0E-24178241IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440744.18E-27254371No hitNo description
CDDcd146601.66E-44254371No hitNo description
PfamPF164214.7E-29257369IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 510 aa     Download sequence    Send to blast
MSTAAGPPDR RASPPRGAAG TTVRPALKRH LAFVTKPPFA PPDDYHSFSS IDSRRLADEA  60
VVVRSPVSTS VSSLRSQIHL RGSRIWNVLF CVECDYMKRK GGMNDSEGES HTQKWSNSPG  120
YTNVSNITNS PFKTPVSAKG GRTQKAKASK EGRSCPPTPI SNAGSPSPLT PASSCRYDSS  180
LGLLTKKFIN LVKHAEDGIL DLNKAAETLE VQKRRIYDIT NVLEGIGLIE KKLKNRIHWK  240
GIESSTSGEV DGDISVLKEE VEKLSLEEQG LDDQIREMQE RLRKLSENEN NRKCLFVTED  300
DIKNLPCFQV FLLLILAYSC KQNETLIAIK APHGTTLEVP DPEEAVDYPQ RRYRIILRST  360
MGPIDVYLIS QFEEKFEEIN GAELPMIPLA SSSESNEQVM TEMVPAECSG KEFEPQTQLS  420
SHVYSDINAS QEFAGGMMKI VPSDVDNDAD YWLLSDADVS ITDMWRTDST VDWNGVDMLN  480
PDFGIISRPQ TPSSGFVEVP TPGANSNHK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A5e-24171242274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapVradi08g00970.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAP0150411e-145AP015041.1 Vigna angularis var. angularis DNA, chromosome 8, almost complete sequence, cultivar: Shumari.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_014512110.10.0transcription factor E2FA
SwissprotQ9FNY01e-147E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A1S3V1C40.0A0A1S3V1C4_VIGRR; transcription factor E2FA
STRINGXP_007145806.10.0(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-140E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]