PlantTFDB
Plant Transcription Factor Database
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Tp57577_TGAC_v2_mRNA3822
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Trifolium
Family AP2
Protein Properties Length: 645aa    MW: 72414.4 Da    PI: 7.0157
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Tp57577_TGAC_v2_mRNA3822genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2378.2e-12290359155
                       AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..........kr...krfslgkfgtaeeAakaaiaarkkleg 55 
                               s+y+GV++++++gr++A+++d  ++  g          ++   k   lg ++ +e+Aa+a+++a++k++g
  Tp57577_TGAC_v2_mRNA3822 290 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqsrkgrqgknVTihsKILILGGYDMEEKAARAYDQAALKYWG 359
                               78*******************9888833456688886611568*************************98 PP

2AP236.11.7e-11417462755
                       AP2   7 rwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                               +++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  Tp57577_TGAC_v2_mRNA3822 417 YRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAYDIAAIKFRG 462
                               78999*******988532...5*************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000181.18E-17290367No hitNo description
SuperFamilySSF541713.33E-13290369IPR016177DNA-binding domain
PfamPF008471.2E-8290359IPR001471AP2/ERF domain
PROSITE profilePS5103216.726291367IPR001471AP2/ERF domain
SMARTSM003809.5E-23291373IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.5E-14291368IPR001471AP2/ERF domain
PRINTSPR003675.5E-5292303IPR001471AP2/ERF domain
PRINTSPR003675.5E-5349369IPR001471AP2/ERF domain
CDDcd000185.87E-23402472No hitNo description
SMARTSM003804.1E-27403476IPR001471AP2/ERF domain
PROSITE profilePS5103218.479403470IPR001471AP2/ERF domain
PfamPF008471.7E-6417462IPR001471AP2/ERF domain
SuperFamilySSF541711.24E-14418470IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.109.3E-16418470IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 645 aa     Download sequence    Send to blast
MKSMMENDDE SVDINNENNW LGFSLSPQMN NQSQHSSSSS ASEIVPLSSS FYNSTPLSNY  60
CFSYGLEHEN NVGLYSLLPI MPLKSDGSLY EMPPQTQAMT PKLENFLGNE AMETPHYACT  120
STTVTETMPL SLDSMFQNQV QHMNNQQQLS YYDLMLEGSK QNQNSSGNFH VSNLGEDNGL  180
SGLKNWVLRN FPASHGHDNS KMIVPVVVDE NVGESCSNIG SMAYGDLHSL SLSMSPSSQS  240
SCVTTSQNMS SAVIDNNSVA IDTKKRGNEK IEQKQIVHRK SIDTFGQRTS QYRGVTRHRW  300
TGRYEAHLWD NSCKKEGQSR KGRQGKNVTI HSKILILGGY DMEEKAARAY DQAALKYWGP  360
STHINFPLEN YQNQLEEMKN MTRQEYVAHL RRKSSGFSRG ASMYRGVTRS YRLLITYRHH  420
QHGRWQARIG RVAGNKDLYL GTFSTQEEAA EAYDIAAIKF RGANAVTNFD IVKYDVEKIM  480
ASSNLLSIEF ARRNKEVVDT TQHIDQNKPN SSAYDNNTQE AILMQKNMVL YQSSQQQNQP  540
RIENERTHQS FSSVSFDNMF HQEVVEEASK MRTHVSNASS LATSLSSSRE GSPDRTSLQN  600
LSGIMPSTAS KLLVTNAPNS NVNSWDPSLH LRTQMPVFAA WTDA*
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapTp57577_TGAC_v2_mRNA3822
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024636092.10.0AP2-like ethylene-responsive transcription factor ANT
SwissprotQ389141e-144ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A396IBY70.0A0A396IBY7_MEDTR; Putative transcription factor AP2-EREBP family
STRINGAES907610.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF91634114
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-121AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]