PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Tp57577_TGAC_v2_mRNA2134
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Trifolium
Family ARF
Protein Properties Length: 687aa    MW: 76724.3 Da    PI: 5.9137
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Tp57577_TGAC_v2_mRNA2134genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B370.42.4e-22141241198
                               EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT- CS
                        B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegD 78 
                               f+k+lt sd++++g +++ +++a+++       ++++ +  +l+ +d++g++W +++i+r++++r++lt+GW+ Fv++++L +gD
  Tp57577_TGAC_v2_mRNA2134 141 FCKTLTASDTSTHGGFSVLRRHADDClppldmtQQPPWQ--ELVATDLHGNEWHFRHIFRGQPRRHLLTTGWSVFVSSKKLVAGD 223
                               99****************************975444444..8******************************************* PP

                               EEEEEE-SSSEE..EEEEE- CS
                        B3  79 fvvFkldgrsefelvvkvfr 98 
                                ++F   + +++el+v+v+r
  Tp57577_TGAC_v2_mRNA2134 224 AFIFL--RGENGELRVGVRR 241
                               *****..449999*****97 PP

2Auxin_resp112.73.4e-37267349183
                Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                               a+ha+st++ F+v+Y+Pr+s+seF+v+++k+++a ++k+svGmRfkm+fe+++++err+sGt+vgv+d +++ W +S+WrsLk
  Tp57577_TGAC_v2_mRNA2134 267 ASHAISTGTLFSVFYKPRTSRSEFIVSINKYLEARNHKLSVGMRFKMRFEGDEVPERRFSGTIVGVEDNKSSVWADSEWRSLK 349
                               789******************************************************************************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.57E-43130270IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.6E-40137256IPR015300DNA-binding pseudobarrel domain
CDDcd100177.82E-21139241No hitNo description
PROSITE profilePS5086311.251141243IPR003340B3 DNA binding domain
SMARTSM010191.2E-21141243IPR003340B3 DNA binding domain
PfamPF023624.4E-20141241IPR003340B3 DNA binding domain
PfamPF065072.7E-35267349IPR010525Auxin response factor
PfamPF023093.3E-11559652IPR033389AUX/IAA domain
PROSITE profilePS5174526.011562655IPR000270PB1 domain
SuperFamilySSF542773.04E-10564639No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009733Biological Processresponse to auxin
GO:0010150Biological Processleaf senescence
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0042802Molecular Functionidentical protein binding
Sequence ? help Back to Top
Protein Sequence    Length: 687 aa     Download sequence    Send to blast
FLHEFLDLSM NDEGAHMASN HLSATISRAG ATNDALYKEL WHACAGPLVT LPREGERVYY  60
FPQGHMEQLE ASMNQGLEQQ MPSFNLPSKI LCKVVNIHLR AEPETDEVYA QITLLPETDQ  120
SEVTSPDDPL PEPPRCTVHS FCKTLTASDT STHGGFSVLR RHADDCLPPL DMTQQPPWQE  180
LVATDLHGNE WHFRHIFRGQ PRRHLLTTGW SVFVSSKKLV AGDAFIFLRG ENGELRVGVR  240
RLMRQQSNVP SSVISSHSMH LGVLATASHA ISTGTLFSVF YKPRTSRSEF IVSINKYLEA  300
RNHKLSVGMR FKMRFEGDEV PERRFSGTIV GVEDNKSSVW ADSEWRSLKV QWDEPSSILR  360
PDRVSPWELE PLVSTPPANA QPTQRNKRSR PPVLPSTIPD SSLQGIWKSP IESPFPYRDP  420
QHGRDLYPSP RFSSTATSFL GLGGNSPASN KSTYWSSRLE NSTEPFLPIA LKESGEKRQG  480
TGNGCRLFGI QLLENSNAEE SLQTVPLSGR VGDDRSVPSL DAESDQHSEP SNVNRSDIPS  540
VSCDADKSCL RSPQESQSRQ IRSCTKVHMQ GMAVGRAVDL TRFDGYEDLL RKLEEMFDIE  600
GELCGATKKW LVVYTDNEDD RMMVGDDPWL EFCSVVRKIF IYTPDEVKKL SPKICLPTNE  660
EGKPCKLDCE AVVNPEDQSS IVGPGC*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A0.0183743357Auxin response factor 1
4ldw_A0.0183743357Auxin response factor 1
4ldw_B0.0183743357Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Acts as repressor of IAA2, IAA3 and IAA7. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16176952}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00097PBMTransfer from AT1G59750Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapTp57577_TGAC_v2_mRNA2134
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1405510.0AC140551.8 Medicago truncatula clone mth2-80i8, complete sequence.
GenBankAC1480970.0AC148097.7 Medicago truncatula clone mth2-15a20, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003592874.10.0auxin response factor 1
RefseqXP_024631839.10.0auxin response factor 1
SwissprotQ8L7G00.0ARFA_ARATH; Auxin response factor 1
TrEMBLA0A2K3P2J10.0A0A2K3P2J1_TRIPR; Auxin response factor
STRINGAES631250.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF68022638
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G59750.40.0auxin response factor 1
Publications ? help Back to Top
  1. Montesinos JC,Pastor-Cantizano N,Robinson DG,Marcote MJ,Aniento F
    Arabidopsis p24δ5 and p24δ9 facilitate Coat Protein I-dependent transport of the K/HDEL receptor ERD2 from the Golgi to the endoplasmic reticulum.
    Plant J., 2014. 80(6): p. 1014-30
    [PMID:25312353]
  2. Marais C, et al.
    The Qb-SNARE Memb11 interacts specifically with Arf1 in the Golgi apparatus of Arabidopsis thaliana.
    J. Exp. Bot., 2015. 66(21): p. 6665-78
    [PMID:26208648]
  3. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  4. Zhang M,Hu X,Zhu M,Xu M,Wang L
    Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis.
    Sci Rep, 2017. 7(1): p. 1395
    [PMID:28469131]