PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010550096.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya
Family E2F/DP
Protein Properties Length: 365aa    MW: 41875.2 Da    PI: 9.4224
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010550096.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP73.81.8e-231984171
         E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                    rkeksL++l  +fl+l+++ +e  ++ln++a +L    v  +rRRiYD++N+Le+++l+++k kn+++wkg
  XP_010550096.1 19 RKEKSLGVLVANFLRLYNRDDEHLIELNDAAGKL---GV--ERRRIYDVVNILESIGLVARKGKNQYSWKG 84
                    79********************************...**..****************************98 PP

2E2F_TDP82.73e-26143223171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                     +keksL+ll+q+f+kl+ +s+ + +tl+++ak+L+se     ++++k+RR+YDi+NV++++nliek     ++k+++rw g
  XP_010550096.1 143 KKEKSLWLLAQNFVKLFLCSDVDLITLDSAAKALLSEsqdpvNMRTKVRRLYDIANVFSSMNLIEKthipeTRKPAYRWLG 223
                     69*****************************************************************************87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.7E-241685IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.24E-161882IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.3E-261984IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.2E-192084IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.109.8E-22140224IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013725.2E-32143223IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.8E-19144223IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.06E-13145224IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 365 aa     Download sequence    Send to blast
MSSVLCQEME SLGRQAYSRK EKSLGVLVAN FLRLYNRDDE HLIELNDAAG KLGVERRRIY  60
DVVNILESIG LVARKGKNQY SWKGFVEVPQ SLNELKEEGL KENFGTSSVS NTEKVSYDDE  120
REGLFSLTSD EQENSSSSKL DSKKEKSLWL LAQNFVKLFL CSDVDLITLD SAAKALLSES  180
QDPVNMRTKV RRLYDIANVF SSMNLIEKTH IPETRKPAYR WLGWKGMSQN RSLVDLNEPK  240
KRRIFGMEIT NLCSKRNKAE FTTNQKPNGK ENAIKGKNQE RIYKMDPQRY SKPNQNKSFV  300
YGPFTPTSVS RINDVGNNDT QTPRLQDLEN LASTHRPQYC NQALTGLLGH YTEAWKSWYS  360
EFSHK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A6e-36182153228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Does not bind retinoblastoma-related proteins. Acts as a growth regulator but is not associated with changes in the expression of cell cycle marker genes or in nuclear ploidy levels. Has no effect on cell proliferation, but may repress cell wall biosynthesis genes during cell elongation in differentiated cells. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15308755}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010550096.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010550096.10.0PREDICTED: E2F transcription factor-like E2FF
SwissprotQ8RWL01e-158E2FF_ARATH; E2F transcription factor-like E2FF
TrEMBLA0A087H6391e-163A0A087H639_ARAAL; Uncharacterized protein
STRINGXP_010550096.10.0(Tarenaya hassleriana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM60032547
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G01330.11e-139DP-E2F-like protein 3
Publications ? help Back to Top
  1. Dohmann EM, et al.
    The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.
    Development, 2008. 135(11): p. 2013-22
    [PMID:18434413]