PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010539053.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya
Family E2F/DP
Protein Properties Length: 405aa    MW: 45124.1 Da    PI: 5.8038
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010539053.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.48.8e-27138203171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt+kf++l+++ ++++++ln +a+ L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  XP_010539053.1 138 RYDSSLGLLTKKFINLIQEDKDRTLDLNYCAEVL---EV--QKRRIYDITNVLEGIGLIEKTTKNHIRWKG 203
                     6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.107.0E-28135205IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.3E-32138203IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.27E-17138201IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023192.2E-24140203IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.10E-40212319No hitNo description
SuperFamilySSF1440741.28E-28213318No hitNo description
PfamPF164217.0E-28217316IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000902Biological Processcell morphogenesis
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0051782Biological Processnegative regulation of cell division
GO:0005667Cellular Componenttranscription factor complex
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 405 aa     Download sequence    Send to blast
MATTSNSGED LTISYNHSPF RFQLLQPLSR DLPPPTNCLF PTTSLPSSAA QALNPPSDHF  60
LAQSYDEALG DIKNHKNQCG KGISGESRDV ATVSVKLEYP EGFGRHGKKA KGFKQFKSRN  120
GKSKAESSSG LNAANNCRYD SSLGLLTKKF INLIQEDKDR TLDLNYCAEV LEVQKRRIYD  180
ITNVLEGIGL IEKTTKNHIR WKGSDSFANL GSQMSRLKSE VASLQSEESQ LNNHIRERQE  240
ALRALEEDEN QRRYLFVTEE DITSLPCFQN RMLLAVKAPI ASSIEVPDPD EDIGFPQRQY  300
RMVVRSTMGP IDVYLISKYG QEHGDAADKL SDHSDQLSHK HAPYATASSA LSLGLDENHY  360
NNSQSFSSSI SAIQKIVTSD TDITADYWFQ SDSEVSLTDL WGNIS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A8e-22138203773PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00190DAPTransfer from AT1G47870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010539053.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010539053.10.0PREDICTED: transcription factor E2FC-like
SwissprotQ9FV701e-139E2FC_ARATH; Transcription factor E2FC
TrEMBLD7KBY01e-140D7KBY0_ARALL; T2E6.2
STRINGXP_010539053.10.0(Tarenaya hassleriana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.21e-129E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]