PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010530521.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Cleomaceae; Tarenaya
Family E2F/DP
Protein Properties Length: 403aa    MW: 44643 Da    PI: 5.4806
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010530521.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.52e-27144209171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+lltqkf++l++++++g+++ln +ak L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  XP_010530521.1 144 RYDSSLGLLTQKFISLIQETKDGTLDLNYCAKVL---EV--QKRRIYDITNVLEGIGLIEKTTKNHIRWKG 209
                     6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.8E-28141211IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.63E-17144207IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.6E-33144209IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.7E-25146209IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146602.86E-39218323No hitNo description
SuperFamilySSF1440744.71E-28219323No hitNo description
PfamPF164218.3E-26223322IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 403 aa     Download sequence    Send to blast
MAAASNSGED PSLTYHRSPF RFQLLQSLYC DPLLSPPPPT TTNCLFPISS PPSSIAQPPN  60
PSSDHCPSHS YDKTFCNGIS SGESRKVAMV PVKLEYPDGK KLESPCEGFG KQAKKAKSLK  120
QSKAGYRKAN AECPSGLNAA NHCRYDSSLG LLTQKFISLI QETKDGTLDL NYCAKVLEVQ  180
KRRIYDITNV LEGIGLIEKT TKNHIRWKGP DSFANLESQM SKLESEVASL HSEEKQLDDR  240
IRERKEALRA FGEDENCRRN LFVTEEDIMS LPCFQNQMLL AVKAPVASSI EVPDPDEDIS  300
FPQPQYRMVV RSTMGPIDVY LISGHKREEG DTTDKLSEQS DQLSHNHASL ALSPGRGENQ  360
CNNSQSSTPS ASGIQKIVTA DTDINADYWF QSDSEVSLTD LWT
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-23144209773PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010530521.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010530521.10.0PREDICTED: transcription factor E2FC-like
SwissprotQ9FV701e-135E2FC_ARATH; Transcription factor E2FC
TrEMBLA0A1J3EBW61e-133A0A1J3EBW6_NOCCA; Transcription factor E2FC (Fragment)
TrEMBLA0A1J3HJH11e-133A0A1J3HJH1_NOCCA; Transcription factor E2FC (Fragment)
STRINGXP_010530521.10.0(Tarenaya hassleriana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.21e-129E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]