PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Traes_4AS_93BB8FB3E.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum
Family AP2
Protein Properties Length: 626aa    MW: 67444.7 Da    PI: 7.0941
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Traes_4AS_93BB8FB3E.1genomeIWGSCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP249.69.6e-16283342155
                    AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                            s+y+GV++++++gr++A+++d  ++ +g  ++ ++++lg ++ +++Aa+a++ a++k++g
  Traes_4AS_93BB8FB3E.1 283 SQYRGVTRHRWTGRYEAHLWDnSCKkDGqtRKgRQVYLGGYDNEDKAARAYDLAALKYWG 342
                            78*******************988898888446**********99*************98 PP

2AP246.97.1e-15385436155
                    AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                            s y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  Traes_4AS_93BB8FB3E.1 385 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFTTQEEAAEAYDVAAIKFRG 436
                            57****************988532...5************************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541711.11E-16283352IPR016177DNA-binding domain
PfamPF008479.9E-12283342IPR001471AP2/ERF domain
CDDcd000181.58E-19283350No hitNo description
PROSITE profilePS5103219.137284350IPR001471AP2/ERF domain
SMARTSM003805.4E-28284356IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.109.7E-16284351IPR001471AP2/ERF domain
PRINTSPR003673.6E-6285296IPR001471AP2/ERF domain
SuperFamilySSF541719.81E-18385445IPR016177DNA-binding domain
CDDcd000188.18E-24385446No hitNo description
PfamPF008475.9E-10385436IPR001471AP2/ERF domain
SMARTSM003806.6E-33386450IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.103.3E-18386444IPR001471AP2/ERF domain
PROSITE profilePS5103219.072386444IPR001471AP2/ERF domain
PRINTSPR003673.6E-6426446IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 626 aa     Download sequence    Send to blast
MRTMASGGNW LGFSLSPHMA MEVPSSSEPD HAQPASASAM SASPTNAATC NLLFSQPAQM  60
AAPPPGYYYV GGAYGDGTST AGVYYSHHPV MPITSDGSLC IMEGMMPSSS PKLEDFLGGG  120
NGSGHDAVTY YSHQQQDQQD QEASRIYHHH QQQQQQLAPY NFQHLTEAEA IYQEATAPMD  180
EAMAAAKNQL VTSYGSCYSN AGMQPLSLSM SPRSQSSSCV SAAPQQHQMA AAAAAASLAA  240
SQGGSNGGGE QEQCVGKKRG TGKGGQKQPV HRKSIDTFGQ RTSQYRGVTR HRWTGRYEAH  300
LWDNSCKKDG QTRKGRQVYL GGYDNEDKAA RAYDLAALKY WGPSTNTNFP LENYREEVEE  360
MKSMTRQEFV AHLRRRSSGF SRGASIYRGV TRHHQHGRWQ ARIGRVAGNK DLYLGTFTTQ  420
EEAAEAYDVA AIKFRGLNAV TNFDITRYDV DKIMESSSLL PGDEARKVKA VEAANHVPAM  480
HNGGGEISHA EEGSSGVWRM VLHGTPQQAA QCTPEVADLQ KGFMGGGDPR SSLHGIAGFD  540
VESAAHDIDV SGKINYSNPS SLVTSLSNSR EGSPERFSLP SLYAKHPNAV SVASMSPWMA  600
MPAPAAAHVL RGPNSSMPVF AAWTDA
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB4585190.0AB458519.1 Triticum aestivum WANT1-2 mRNA for AP2 transcription factor, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020159300.10.0AP2-like ethylene-responsive transcription factor ANT isoform X2
SwissprotQ389141e-139ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A3B6HSZ20.0A0A3B6HSZ2_WHEAT; Uncharacterized protein
TrEMBLA0A446QPC00.0A0A446QPC0_TRITD; Uncharacterized protein
STRINGTraes_4AS_93BB8FB3E.10.0(Triticum aestivum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP94838133
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-113AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Brenchley R, et al.
    Analysis of the bread wheat genome using whole-genome shotgun sequencing.
    Nature, 2012. 491(7426): p. 705-10
    [PMID:23192148]
  3. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  4. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  5. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  6. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  7. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  8. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  9. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  10. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  11. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  12. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]