PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sevir.4G017000.1.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Panicoideae; Panicodae; Paniceae; Cenchrinae; Setaria
Family GRAS
Protein Properties Length: 612aa    MW: 64880.6 Da    PI: 6.4724
Description GRAS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sevir.4G017000.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1GRAS386.43.3e-1182165852374
                GRAS   2 velLlecAeavssgdlelaqalLarlselaspdg.dpmqRlaayfteALaarlarsvselykalppsetsekn.sseelaalklfsevsPi 90 
                         v +L++cA+ ++++++++a+ +Larl e+asp+g +pm+R+aayf+eALa r++r++++l++  pp+e ++    ++ ++al++++ v+Pi
  Sevir.4G017000.1.p 216 VVALTACADSLAARNHNAASYYLARLGEMASPAGpTPMHRVAAYFAEALALRVVRTWPHLFDVTPPRELTDGAaGDDDATALRILNAVTPI 306
                         5689***************************************************************9998777999************** PP

                GRAS  91 lkfshltaNqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgspesgskeeleetgerLakfAeelgvpfefnvl 181
                         ++f h+t N+ +l+a++g++rvHiiDfdi+qGlQWp Llq+La R+ +p+++RiTgvg+    s++el+etg rL ++A++lg+ fef++ 
  Sevir.4G017000.1.p 307 PRFLHFTLNERMLRAFDGHDRVHIIDFDIKQGLQWPGLLQSLAMRAVPPAHVRITGVGE----SRQELQETGARLGRVAATLGLAFEFHA- 392
                         ***********************************************************....9**************************. PP

                GRAS 182 vakrledleleeLrvkpgEalaVnlvlqlhrlldesvsleserdevLklvkslsPkvvvvveqeadhnsesFlerflealeyysalfdsl. 271
                         v++rled++l++L+vk+gE++aVn+vl+ hrll++++  +    ++L l +s+ + ++ + e+e  +ns+++ +rf++al+yy+a fd++ 
  Sevir.4G017000.1.p 393 VVDRLEDVRLWMLHVKRGECVAVNCVLAAHRLLRDDTGAAL--ADFLGLARSTGAAILLLGEHEDALNSGRWEARFARALRYYAAAFDAVd 481
                         7********************************87777666..89*********************************************9 PP

                GRAS 272 eaklpreseerikvErellgreivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvksdgyrveee..sgslvl 360
                         +a+l+ +s +r k E++ ++rei+n+va e a+r+erhe+++ W++r+ee GF+++ +++++a+q +++ r+++   y+v+ +   + l+l
  Sevir.4G017000.1.p 482 AAGLSDASPARLKAEEM-FAREIRNAVAFEAADRFERHESFAGWQQRMEEGGFQNAGIGDREAMQGRMIARMFAPGNYSVQAQgdGEGLTL 571
                         999**************.********************************************************555*999554367788* PP

                GRAS 361 gWkdrpLvsvSaWr 374
                          W d+p+++vSaW+
  Sevir.4G017000.1.p 572 QWLDQPMYTVSAWT 585
                         *************6 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5098555.324189563IPR005202Transcription factor GRAS
PfamPF035141.1E-115216585IPR005202Transcription factor GRAS
Sequence ? help Back to Top
Protein Sequence    Length: 612 aa     Download sequence    Send to blast
MLAGCSFSSS RHQMSTAQRF DILPYGFSKR SNRGDGGGGG APRVAAGDAR TGGAATCSFR  60
AHPAPPVTQA VSWGAKPEPG GNGAGGVWER SRAVKRAHEE YGGPVVRAKR TRMGGDGDEV  120
WFHQPIAGTV QAAGGGEGEQ PEEEKAFLVP SAAAFPHAGT SLAAAKEEEF SKSPSNSPAS  180
SGGTDGGSSA VPRPELHARN GVPAPEEAGR EAMELVVALT ACADSLAARN HNAASYYLAR  240
LGEMASPAGP TPMHRVAAYF AEALALRVVR TWPHLFDVTP PRELTDGAAG DDDATALRIL  300
NAVTPIPRFL HFTLNERMLR AFDGHDRVHI IDFDIKQGLQ WPGLLQSLAM RAVPPAHVRI  360
TGVGESRQEL QETGARLGRV AATLGLAFEF HAVVDRLEDV RLWMLHVKRG ECVAVNCVLA  420
AHRLLRDDTG AALADFLGLA RSTGAAILLL GEHEDALNSG RWEARFARAL RYYAAAFDAV  480
DAAGLSDASP ARLKAEEMFA REIRNAVAFE AADRFERHES FAGWQQRMEE GGFQNAGIGD  540
REAMQGRMIA RMFAPGNYSV QAQGDGEGLT LQWLDQPMYT VSAWTPMGDG GGGGSTVSAS  600
VSTTASHSQQ S*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3g_A9e-5922258626380Protein SCARECROW
5b3h_A8e-5922258625379Protein SCARECROW
5b3h_D8e-5922258625379Protein SCARECROW
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor that acts as positivie regulator of brassinosteroid (BR) signaling (PubMed:19220793, PubMed:22685166). Functions downstream of BRI1 and GSK2 to modulate BR responses. Acts as a direct target of GSK2 kinase to mediate BR responses (PubMed:22685166). Involved in feedback inhibition of BR biosynthetic genes. Repressed by BZR1 (PubMed:19220793). {ECO:0000269|PubMed:19220793, ECO:0000269|PubMed:22685166}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSevir.4G017000.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by 24-epibrassinolide. {ECO:0000269|PubMed:19220793}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAP0011680.0AP001168.1 Oryza sativa Japonica Group genomic DNA, chromosome 6, clone:P0425F02.
GenBankAP0028380.0AP002838.2 Oryza sativa Japonica Group genomic DNA, chromosome 6, BAC clone:OSJNBa0038F22.
GenBankAP0149620.0AP014962.1 Oryza sativa Japonica Group DNA, chromosome 6, cultivar: Nipponbare, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004964401.10.0protein DWARF AND LOW-TILLERING
SwissprotQ9LWU90.0DLT_ORYSJ; Protein DWARF AND LOW-TILLERING
TrEMBLK3Y2010.0K3Y201_SETIT; Uncharacterized protein
STRINGSi008220m0.0(Setaria italica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP64043455
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G63100.11e-124GRAS family protein
Publications ? help Back to Top
  1. Tong H,Chu C
    Roles of DLT in fine modulation on brassinosteroid response in rice.
    Plant Signal Behav, 2009. 4(5): p. 438-9
    [PMID:19816111]
  2. Li W, et al.
    Identification and characterization of dwarf 62, a loss-of-function mutation in DLT/OsGRAS-32 affecting gibberellin metabolism in rice.
    Planta, 2010. 232(6): p. 1383-96
    [PMID:20830595]
  3. Tong H, et al.
    DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice.
    Plant Cell, 2012. 24(6): p. 2562-77
    [PMID:22685166]
  4. Zhang C,Bai MY,Chong K
    Brassinosteroid-mediated regulation of agronomic traits in rice.
    Plant Cell Rep., 2014. 33(5): p. 683-96
    [PMID:24667992]
  5. Yang C,Shen W,He Y,Tian Z,Li J
    OVATE Family Protein 8 Positively Mediates Brassinosteroid Signaling through Interacting with the GSK3-like Kinase in Rice.
    PLoS Genet., 2016. 12(6): p. e1006118
    [PMID:27332964]