PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID SapurV1A.0510s0180.1.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Salix
Family E2F/DP
Protein Properties Length: 458aa    MW: 50108 Da    PI: 4.7291
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
SapurV1A.0510s0180.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP83.61.6e-26146211171
                 E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                             r+++sL llt++f++l++++++gi++ln++a++L   +v  ++RRiYDi+NVLe+++liek+ kn+irwkg
  SapurV1A.0510s0180.1.p 146 RYDSSLSLLTKRFVDLFKHADDGILDLNNAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRIRWKG 211
                             6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.9E-28143213IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467854.99E-17146209IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.9E-33146211IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.8E-24148211IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440741.46E-31225327No hitNo description
PfamPF164211.0E-32227326IPR032198E2F transcription factor, CC-MB domain
CDDcd146601.94E-47227327No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 458 aa     Download sequence    Send to blast
MSGGAKASTR PAAPPPSSGP IQPPFSRHLA FATMKPSFVP PDDYHRFSSP STSRVAADRD  60
AEAIVLRSPQ LKRKSAMDDN GVGSSNQASS PGCTNISNIP FRTPVSAKGG RTYNKSKASK  120
GSGAGPQTPV SKSDCASPLT PAGSCRYDSS LSLLTKRFVD LFKHADDGIL DLNNAAETLE  180
VQKRRIYDIT NVLEGIGLIE KTLKNRIRWK GIDASRPGQV EVDATLLQEE IAKLTMEEHI  240
LDDQIREMQE RLRDLSEDEN NQKWLFVTEE DIKSLPCFLN ETLIAIKAPH GTTLEVPDPD  300
EAVDYPQRRY KIILRSSMGP IDVYLVSRFE DNFEEMNNVE ASESIPLASV STSHGNPMTE  360
ITTDVRTQER SGSLVQQAQT MFSDPYATQE LGGMTKIVPS DINDDSDYWL LSDAGISITD  420
MWKTSSNIEW ADFGVTDVQT PRTQTPSPGI TEVPPGV*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-22141212274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00293DAPTransfer from AT2G36010Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapSapurV1A.0510s0180.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011046879.10.0PREDICTED: transcription factor E2FA-like
SwissprotQ9FNY01e-161E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A2K2A5E00.0A0A2K2A5E0_POPTR; Uncharacterized protein
STRINGPOPTR_0006s22150.10.0(Populus trichocarpa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-162E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]