PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sopen06g030430.2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon
Family E2F/DP
Protein Properties Length: 363aa    MW: 40318.9 Da    PI: 4.2715
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sopen06g030430.2genomespennView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP72.64.4e-2343106371
           E2F_TDP   3 eksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                       ++sL+ lt+kf++l+++se+g+++ln++a++L   +v  k+RR+YD++ VLe+++liekk+ n i+wkg
  Sopen06g030430.2  43 DNSLGFLTKKFINLIKHSEDGVLDLNKAADTL---EV--KKRRLYDVTSVLEGIGLIEKKSLNMIQWKG 106
                       89******************************...99..9***************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.6E-2540108IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-3041106IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.26E-1642104IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023197.3E-2243106IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.02E-41117223No hitNo description
SuperFamilySSF1440746.28E-30119223No hitNo description
PfamPF164212.1E-28122221IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 363 aa     Download sequence    Send to blast
MQTPISGKAG KSQKAPKSSA QATSSLGFRS GNNVTPVGPC CYDNSLGFLT KKFINLIKHS  60
EDGVLDLNKA ADTLEVKKRR LYDVTSVLEG IGLIEKKSLN MIQWKGLDVS RPGEVDESVT  120
SLQAEVENLT IEESILDEQI REKQERLRVL SEDENNQRWL FVTEDDIKSL PCLQNYTLIA  180
IRFPHGTSLE VPDPNEAVDY PQRRYSIVIR STMGPIDVYL ISKFEEKFKQ ITTVEEPSTM  240
PSTSGFIEKE TAALPVDDGR GVGVGMEEQE NQRECPDAGT SQNPVSGIIK IVPDFDPLQN  300
QEEDYLFLSD ANVSNTDMWT ESVRDALDSI YEDYSIADVR SPHAQTPPSS TTELTSANTT  360
EAE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-2336107274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027773767.10.0transcription factor E2FB-like
SwissprotQ9FV711e-115E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A3Q7H2M10.0A0A3Q7H2M1_SOLLC; Uncharacterized protein
STRINGSolyc06g074010.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10772484
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.31e-119E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]