PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_06605.1_g00003.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family bHLH
Protein Properties Length: 230aa    MW: 25793.3 Da    PI: 6.0549
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_06605.1_g00003.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH38.91.6e-1274120554
                              HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
                      HLH   5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                              +  rE+ RRd++N++f+eL ++l +    +++K++K+ iL  Av+ + +L
  Sme2.5_06605.1_g00003.1  74 KAHREKMRRDKLNDRFQELSSILEPG---KQPKMDKSVILGDAVRMVVQL 120
                              678**********************9...9**************987766 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088812.66569120IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.36E-873125No hitNo description
PfamPF000104.9E-1073120IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.1E-975126IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474597.07E-1475144IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.6E-1375142IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 230 aa     Download sequence    Send to blast
MAETDEDGSN WLIELGLMED LPALEPNAQW PSNAFSLPNN ISSGLEDSYG NSDSLKECGS  60
KKRVRSGACA SDSKAHREKM RRDKLNDRFQ ELSSILEPGK QPKMDKSVIL GDAVRMVVQL  120
RDEAQKLKES YNNLQEKVIE LKAEKNELRD EKQKLKAEKE KLEQHLKALN TQPGFLPHPP  180
AMPSPFSAPH QVFASKMMPY LGYPGIPMWQ FVPPAAVDTS EDHSLRPPVA
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269|PubMed:17028341}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKC1583070.0KC158307.1 Solanum lycopersicum AFLP fragment TGG1, mRNA sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015066100.11e-166transcription factor ILR3-like
SwissprotQ9FH373e-80ILR3_ARATH; Transcription factor ILR3
TrEMBLM1BYR31e-164M1BYR3_SOLTU; Uncharacterized protein
STRINGSolyc02g079970.2.11e-165(Solanum lycopersicum)
STRINGPGSC0003DMT4000559071e-165(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA9502482
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G54680.12e-68bHLH family protein
Publications ? help Back to Top
  1. Li X,Zhang H,Ai Q,Liang G,Yu D
    Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana.
    Plant Physiol., 2016. 170(4): p. 2478-93
    [PMID:26921305]
  2. Aparicio F,Pallás V
    The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response.
    Mol. Plant Pathol., 2017. 18(2): p. 173-186
    [PMID:26929142]
  3. Liang G,Zhang H,Li X,Ai Q,Yu D
    bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana.
    J. Exp. Bot., 2017. 68(7): p. 1743-1755
    [PMID:28369511]
  4. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  5. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  6. Min JH, et al.
    Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element.
    Front Plant Sci, 2017. 8: p. 2100
    [PMID:29321786]
  7. Samira R, et al.
    The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis.
    Plant Mol. Biol., 2018. 97(4-5): p. 297-309
    [PMID:29882068]