PlantTFDB
Plant Transcription Factor Database
PlantRegMap/PlantTFDB v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_02585.1_g00003.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family bHLH
Protein Properties Length: 202aa    MW: 22323.3 Da    PI: 5.4087
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_02585.1_g00003.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH31.24e-1076118449
                              HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHH CS
                      HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAve 49 
                              ++  rE+ RR+++N++f eL  ll +    + +K +K++iL  Ave
  Sme2.5_02585.1_g00003.1  76 SKACREKLRREKLNDKFMELAALLEPG---RPPKTDKSAILVDAVE 118
                              6789**********************8...89************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088811.25572123IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.41E-875127No hitNo description
Gene3DG3DSA:4.10.280.101.0E-976143IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.2E-776118IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.44E-977150IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.7E-478128IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 202 aa     Download sequence    Send to blast
MVQPENTNWL YDYNFEDIVV PDASFSVSGF SWSVQGYNGS TNASVDIDGS FGESDCLKES  60
SFKKRTRAES CTSSSSKACR EKLRREKLND KFMELAALLE PGRPPKTDKS AILVDAVEKN  120
ELRDEKQRLK SEKEKLEQQL KTMSAQPGYL PPSMPGAFAA PVQAAGTKLV PIISYPGVAM  180
WQFMPPAAID TSQDHVLRPP VA
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269|PubMed:17028341}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC2331221e-117AC233122.7 Solanum lycopersicum strain Heinz 1706 chromosome 10 clone hba-12d17 map 10, complete sequence.
GenBankAC2401921e-117AC240192.1 Solanum lycopersicum strain Heinz 1706 chromosome 10 clone hba-107b5 map 10, complete sequence.
GenBankAC2402241e-117AC240224.1 Solanum lycopersicum strain Heinz 1706 chromosome 10 clone sle-61e6 map 10, complete sequence.
GenBankHG9754491e-117HG975449.1 Solanum pennellii chromosome ch10, complete genome.
GenBankHG9755221e-117HG975522.1 Solanum lycopersicum chromosome ch10, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006352486.11e-132PREDICTED: transcription factor ILR3-like
SwissprotQ9FH374e-82ILR3_ARATH; Transcription factor ILR3
TrEMBLM1B5C51e-130M1B5C5_SOLTU; Uncharacterized protein
STRINGPGSC0003DMT4000374051e-131(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA9502482
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G54680.14e-70bHLH family protein
Publications ? help Back to Top
  1. Li X,Zhang H,Ai Q,Liang G,Yu D
    Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana.
    Plant Physiol., 2016. 170(4): p. 2478-93
    [PMID:26921305]
  2. Aparicio F,Pallás V
    The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response.
    Mol. Plant Pathol., 2017. 18(2): p. 173-186
    [PMID:26929142]
  3. Liang G,Zhang H,Li X,Ai Q,Yu D
    bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana.
    J. Exp. Bot., 2017. 68(7): p. 1743-1755
    [PMID:28369511]
  4. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  5. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  6. Min JH, et al.
    Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element.
    Front Plant Sci, 2017. 8: p. 2100
    [PMID:29321786]
  7. Samira R, et al.
    The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis.
    Plant Mol. Biol., 2018. 97(4-5): p. 297-309
    [PMID:29882068]