PlantTFDB
Plant Transcription Factor Database
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_02104.1_g00004.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family bHLH
Protein Properties Length: 634aa    MW: 69170 Da    PI: 5.2527
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_02104.1_g00004.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH391.4e-12461506454
                              HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
                      HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                              +h e+Er+RR+++N++f  Lr ++P+       K++Ka+ L  A+ YI++L
  Sme2.5_02104.1_g00004.1 461 NHVEAERQRREKLNQRFYALRAVVPNV-----SKMDKASLLGDAIAYINDL 506
                              799***********************6.....5****************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142153.9E-5570258IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.066457506IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474597.72E-18458530IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000838.19E-15460511No hitNo description
Gene3DG3DSA:4.10.280.103.3E-18461527IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000104.8E-10461506IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003539.4E-16463512IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 634 aa     Download sequence    Send to blast
MELTEYRLWS SNTNTINSSD DNMMDAFLSS DPPSFWPGGN TTAPSNRTSI SPAPENGGGD  60
TMPFFSQESL QQRLQTLIDG AHESWAYAIF WQSSSSVVDF ASPSVLGWGD GYYKGEEDKN  120
KRKTNSSSPD FLAEQEHRKK VLRELNSLIS GVQTAVGGAD DSVDEEVTDT EWFFLISMTQ  180
SFVNGNGLPG LAMYSSSPIW VTGAEGLAAS QCERARQAQG FGLQTIVCIP SANGVVELGS  240
TELIFQSSDL MNKVKYLFNF NIDMGSVTGS GSGSGVVHPE PDPSALWLTD PSSSVVEANV  300
SKQLVFGNEN SENGAKHSQQ TQGFFTRELN FSSYGFDGSS TRNKNGKTSV SCKPESGEIL  360
NFGDGNKRSG SLFSGQSKFG PRPGLVEENK NKKRGNNEEG ILSFVSGVIL PTSTTEKSGG  420
GGDSDHSDLE ASVVKETVVE PEKKPRKRGR KPANGREEPL NHVEAERQRR EKLNQRFYAL  480
RAVVPNVSKM DKASLLGDAI AYINDLKLKV QNSESDKEDL RSQIECLRKE LANKGSSNYP  540
GPLPSNQDLK IVDMDIDVKV IGWDAMIRIQ CSKKNHPAAR LMAALKDLDL DVHHASVSVV  600
NDIMIQQATV KMGSRLYAQE QLRIALTSKI AESR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rqw_A5e-70632612195Transcription factor MYC3
4rqw_B5e-70632612195Transcription factor MYC3
4rs9_A5e-70632612195Transcription factor MYC3
4yz6_A5e-70632612195Transcription factor MYC3
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1442450KKPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds to the G-box motif (5'-AACGTG-3') found in a number of promoters of jasmonate-induced genes (PubMed:15231736). Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371, PubMed:30518626). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). Acts synergistically with EOT1 in the transactivation of TPS5 (PubMed:24884371). Involved in type VI glandular trichome development (PubMed:30518626). Involved in the activation of terpene synthases required for volatile mono- and sesquiterpenes synthesis by the glandular cells of type VI trichomes (PubMed:30518626). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24884371, ECO:0000269|PubMed:30518626}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by methyl jasmonate and wounding. {ECO:0000269|PubMed:15231736}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ6305060.0AJ630506.1 Solanum tuberosum partial mRNA for MYC transcription factor (jamyc10 gene).
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015085548.10.0transcription factor MYC4-like
SwissprotA0A060KY900.0MYC1_SOLLC; Transcription factor MYC1
TrEMBLQ700B90.0Q700B9_SOLTU; MYC transcription factor (Fragment)
STRINGXP_009800420.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA33002449
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32640.11e-163bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Spyropoulou EA,Haring MA,Schuurink RC
    RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters.
    BMC Genomics, 2014. 15: p. 402
    [PMID:24884371]
  3. Xu J, et al.
    SlMYC1 Regulates Type VI Glandular Trichome Formation and Terpene Biosynthesis in Tomato Glandular Cells.
    Plant Cell, 2018. 30(12): p. 2988-3005
    [PMID:30518626]