PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_00377.1_g00002.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family ERF
Protein Properties Length: 344aa    MW: 37979.6 Da    PI: 4.4356
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_00377.1_g00002.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP256.66.2e-1874123255
                      AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                              +y+G+r+++ +g+W+AeIrdp++     r++lg+f +aeeAa+a++  +++++g
  Sme2.5_00377.1_g00002.1  74 QYRGIRQRP-WGKWAAEIRDPRK---GIRVWLGTFNSAEEAARAYDVEARRIRG 123
                              69*******.**********954...3************************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.101.2E-3174132IPR001471AP2/ERF domain
SMARTSM003804.8E-3674137IPR001471AP2/ERF domain
PROSITE profilePS5103223.9274131IPR001471AP2/ERF domain
CDDcd000181.26E-3174133No hitNo description
SuperFamilySSF541718.5E-2274132IPR016177DNA-binding domain
PfamPF008478.9E-1175123IPR001471AP2/ERF domain
PRINTSPR003675.1E-117586IPR001471AP2/ERF domain
PRINTSPR003675.1E-1197113IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 344 aa     Download sequence    Send to blast
MCGGAIISDL VPPSRISRRL TADFLWDEFE ADFQHFKDYS DDDEDVKAFG SKSVRSADSS  60
SDAERSSKRK RKNQYRGIRQ RPWGKWAAEI RDPRKGIRVW LGTFNSAEEA ARAYDVEARR  120
IRGKKAKVNF PDDAPVAASR RVVKPNPQEA LQEENLNTVQ PNVAYINNLD AGSDESFSFF  180
EEKPAANQCG YKNTCFTAGD MGLGSVSPSA GANVYFSSDE GSNTFDCSDF DWGELGARTP  240
DMSSVLSEVL ESNGSHFDED ARPEKKQKSS SSTSLTGDGN TVNTLSEELS AFESQMKFLQ  300
IPYLEGNWDS SVDAFLNTSA IQEGGNAMDL WSFDDVPSLM GGVY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A3e-2074131260ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269|PubMed:22020282, ECO:0000269|PubMed:22530619}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269|PubMed:22020282}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKC1643470.0KC164347.1 Solanum tuberosum clone RSI9 ethylene responsive factor 1 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001305599.10.0ethylene-responsive transcription factor RAP2-12-like
SwissprotQ9SSA83e-65RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBLM1A1E20.0M1A1E2_SOLTU; Ethylene responsive factor 1
STRINGPGSC0003DMT4000125470.0(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA14462466
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G53910.31e-56related to AP2 12
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Kosmacz M, et al.
    The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration.
    Plant Cell Environ., 2015. 38(6): p. 1094-103
    [PMID:25438831]
  3. Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F
    Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana.
    Plant Sci., 2015. 236: p. 37-43
    [PMID:26025519]
  4. Gasch P, et al.
    Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    Plant Cell, 2016. 28(1): p. 160-80
    [PMID:26668304]
  5. Gonzali S, et al.
    Universal stress protein HRU1 mediates ROS homeostasis under anoxia.
    Nat Plants, 2015. 1: p. 15151
    [PMID:27251529]
  6. Paul MV, et al.
    Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia.
    Plant Physiol., 2016. 172(1): p. 141-53
    [PMID:27372243]
  7. Shahzad Z, et al.
    A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics.
    Cell, 2016. 167(1): p. 87-98.e14
    [PMID:27641502]
  8. Yao Y, et al.
    ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis.
    New Phytol., 2017. 213(4): p. 1667-1681
    [PMID:28164334]
  9. Giuntoli B,Licausi F,van Veen H,Perata P
    Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants.
    Front Plant Sci, 2017. 8: p. 591
    [PMID:28487707]
  10. Yao Y,Chen X,Wu AM
    ERF-VII members exhibit synergistic and separate roles in Arabidopsis.
    Plant Signal Behav, 2017. 12(6): p. e1329073
    [PMID:28537474]
  11. Eysholdt-Derzsó E,Sauter M
    Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling.
    Plant Physiol., 2017. 175(1): p. 412-423
    [PMID:28698356]
  12. Giuntoli B, et al.
    Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana.
    Plant Cell Environ., 2017. 40(10): p. 2333-2346
    [PMID:28741696]