PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_00047.1_g00028.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family bHLH
Protein Properties Length: 638aa    MW: 71743 Da    PI: 9.0815
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_00047.1_g00028.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.41.1e-12467513455
                              HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                      HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                              +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  Sme2.5_00047.1_g00028.1 467 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYITELQ 513
                              799***********************66......*****************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142157.3E-5591278IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.85463512IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.80E-13466517No hitNo description
SuperFamilySSF474594.32E-18466525IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.0E-17467524IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.7E-10467513IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.2E-16469518IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 638 aa     Download sequence    Send to blast
MEWIHGQPIS RALRSFPSSS TLANSGEQQA SQLGTFLATT APQAPSDLKR DYMVEALQQL  60
GIDVRPLMRP PSRKPYPDWI DRVHQFQKGY KHKLSDLVER PNAANFSWNY AIFWQISRSK  120
SGELVLGWGD GCCREPREGE ERDVKRIFNL RLDDEAQQRM RKRVLQKLHI LFGGTDDDNY  180
AFGLDRVTDT EMFFLASMYF SFPRGEGGPG KCFGSGKHLW LSDALTSSLD YCARSFLAKS  240
AGMQTIVMIP TDVGVVELGS VRSIPESLEL LQNIKSCFSS FLSLVRDKQA AGKAVVPENN  300
ERNNPRLLNG NPKIFGHDLN LSTQFREKLA VRKAEERPWD IYQNGNRMPF VNAQNGLHAA  360
ACSQFSNMKP GKPGELYGHQ TPAHNLLNRG KEELRLNNFQ HQKPAARMQI DFTGSTSRPI  420
VSPAHTVESE HSDVEASFKE DRAGPVDEKR PRKRGRKPAN GREEPLNHVE AERQRREKLN  480
QRFYALRAVV PNISKMDKAS LLGDAIAYIT ELQKKLRDME SERELRLGST SRDAMASEDS  540
PSSENQIQGP DIKIEAANDE VIVRVSCPLE THPISRVIQT FKEAQINIVE SKLSAGNGTV  600
YHTFVLKSSG SEQLTKERLL AAFSNESHSL RQLSPVGQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A6e-29461523264Transcription factor MYC2
5gnj_B6e-29461523264Transcription factor MYC2
5gnj_E6e-29461523264Transcription factor MYC2
5gnj_F6e-29461523264Transcription factor MYC2
5gnj_G6e-29461523264Transcription factor MYC2
5gnj_I6e-29461523264Transcription factor MYC2
5gnj_M6e-29461523264Transcription factor MYC2
5gnj_N6e-29461523264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1448456KRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754400.0HG975440.1 Solanum pennellii chromosome ch01, complete genome.
GenBankHG9755130.0HG975513.1 Solanum lycopersicum chromosome ch01, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015063116.10.0transcription factor bHLH13-like
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLM0ZH360.0M0ZH36_SOLTU; Uncharacterized protein
STRINGSolyc01g096050.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA35852348
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.31e-161bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]