PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Sme2.5_00014.1_g00019.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum
Family bHLH
Protein Properties Length: 477aa    MW: 53223.4 Da    PI: 7.3076
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Sme2.5_00014.1_g00019.1genomeEGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH407e-13331377455
                              HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                      HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                              +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  Sme2.5_00014.1_g00019.1 331 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYITDLQ 377
                              799***********************66......*****************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142153.9E-4449227IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.66327376IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474594.19E-18327393IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.18E-13330381No hitNo description
PfamPF000102.1E-10331377IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.6E-17331395IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.7E-15333382IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 477 aa     Download sequence    Send to blast
MSEKLFLKGE DKVIMEEVLG SEAVEFFSWS ASNHMLTEFT SSRGDLGVQE ALCKIVEGSD  60
WTYAIYWQVA KSKSGKSALI WGDGHCREAK LGQSERGDDS RHQKMMDGNK KKMVLQKIHT  120
CFGGSEDDNI AAKLESVSDV EVFYLTSMYY IFPFDKASTP SQSFNSARSI WVSDLKGCVE  180
HFQSRSYLAK LARFETLVFV PLKSGVVELG SVKSIPEDQN LIQMVKTSVV VSNPPQPKTI  240
PKIFGRELSL GGAKSGPISI NFSPKVEDEL TFASDAYEVQ AALGTSQVYG SSSNGYRSDE  300
GEGKLYKEEL DERKPRKRGR KPANGREEAL NHVEAERQRR EKLNQRFYAL RAVVPNISKM  360
DKASLLGDAI AYITDLQARI RVLDAEKEMV GDKQKQQVIP EIDFHQRQDD AVVRVSCPLN  420
VHPVSRVLKT FQEHQVVAQE SNVSLTENSK LVHTFSIRAP GPAAEDLKEK LTAALSK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A3e-27325387264Transcription factor MYC2
5gnj_B3e-27325387264Transcription factor MYC2
5gnj_E3e-27325387264Transcription factor MYC2
5gnj_F3e-27325387264Transcription factor MYC2
5gnj_G3e-27325387264Transcription factor MYC2
5gnj_I3e-27325387264Transcription factor MYC2
5gnj_M3e-27325387264Transcription factor MYC2
5gnj_N3e-27325387264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1312320RKPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00099PBMTransfer from AT4G16430Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754450.0HG975445.1 Solanum pennellii chromosome ch06, complete genome.
GenBankHG9755180.0HG975518.1 Solanum lycopersicum chromosome ch06, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006352746.10.0PREDICTED: transcription factor bHLH3
SwissprotA0A3Q7H2160.0MTB3_SOLLC; Transcription factor MTB3
TrEMBLM1BS130.0M1BS13_SOLTU; Uncharacterized protein
STRINGPGSC0003DMT4000516720.0(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA66692433
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-163bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]