PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Solyc07g063410.2.1
Common NameJA2L
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon
Family NAC
Protein Properties Length: 357aa    MW: 40091.7 Da    PI: 7.5851
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Solyc07g063410.2.1genomeITAGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM168.13e-52141391128
                 NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdke 91 
                         lppGfrF Ptdeel+v+yL++kv+g++++l ++i+e+d+yk++Pw Lp+k+  +ekewyfFs+rd+ky++g+r+nr++ sgyWkatg+dk 
  Solyc07g063410.2.1  14 LPPGFRFYPTDEELLVQYLCRKVAGHDFSL-QIIAEIDLYKFDPWVLPSKAIFGEKEWYFFSPRDRKYPNGSRPNRVAGSGYWKATGTDKV 103
                         79***************************9.89***************7777799************************************ PP

                 NAM  92 vlskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                         +++ +g++vg+kk Lvfy g+apkg+kt+W+mheyrl
  Solyc07g063410.2.1 104 ITT-DGRKVGIKKALVFYIGKAPKGTKTNWIMHEYRL 139
                         *99.999****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019417.59E-678162IPR003441NAC domain
PROSITE profilePS5100560.52114162IPR003441NAC domain
PfamPF023653.3E-2615139IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0009737Biological Processresponse to abscisic acid
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 357 aa     Download sequence    Send to blast
MGVQEMDPLT QLSLPPGFRF YPTDEELLVQ YLCRKVAGHD FSLQIIAEID LYKFDPWVLP  60
SKAIFGEKEW YFFSPRDRKY PNGSRPNRVA GSGYWKATGT DKVITTDGRK VGIKKALVFY  120
IGKAPKGTKT NWIMHEYRLS EPTTKTGSSR LDDWVLCRIY KKNSGGQKSS CSDLQNKDIS  180
HASSSSSSSQ FDDMLESLPA IEDRYFSLPR VNSIRNFQQN DKINLQQLSS GNFDWAAMAG  240
LNSFPELRTG NQVPTPGNQT PVLINTNQYH NHNDNLNNFN EFFANSTALN FHGEVKFEGG  300
VDQEVESSVR AQRLNSVNPG FFQENSTGFS SSYTNSVPDP FGIRYPTQTV NMGFTG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3swm_A1e-11111687174NAC domain-containing protein 19
3swm_B1e-11111687174NAC domain-containing protein 19
3swm_C1e-11111687174NAC domain-containing protein 19
3swm_D1e-11111687174NAC domain-containing protein 19
3swp_A1e-11111687174NAC domain-containing protein 19
3swp_B1e-11111687174NAC domain-containing protein 19
3swp_C1e-11111687174NAC domain-containing protein 19
3swp_D1e-11111687174NAC domain-containing protein 19
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Les.117400.0callus| flower| fruit| leaf| root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in guard cells of the epidermis. {ECO:0000269|PubMed:25005917}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). Involved in jasmonate- and coronatine-mediated stomatal reopening in response to Pseudomonas syringae pv tomato DC3000 infection (PubMed:25005917). Regulates the expression of threonine deaminase 2 (TD2) through promoter binding (PubMed:28733419). {ECO:0000269|PubMed:25005917, ECO:0000269|PubMed:28733419}.
Function -- GeneRIF ? help Back to Top
  1. Molecular mechanisms by which JA2 (jasmonic acid2) and JA2L (JA2-like), two homologous NAC TFS in tomato, regulate P.s. tomato DC3000-triggered stomatal movement is different. JA2 regulates the expression of an abscisic acid biosynthetic gene. Jasmonic acid (JA) and coronatine(COR) activate JA2L expession, and genetic manipulation of JA2L revealed its positive role in JA/COR-mediated stomatal reopeneing.
    [PMID: 25005917]
Cis-element ? help Back to Top
SourceLink
PlantRegMapSolyc07g063410.2.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by jasmonate (JA) (PubMed:25005917, PubMed:28733419, PubMed:30610166). Induced by wounding (PubMed:28733419, PubMed:25005917). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced by coronatine (PubMed:25005917). {ECO:0000269|PubMed:25005917, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001306107.10.0JA2-like
SwissprotA0A3Q7HH640.0JA2L_SOLLC; NAC domain-containing protein JA2L
TrEMBLM1BP490.0M1BP49_SOLTU; Uncharacterized protein
STRINGSolyc07g063410.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA31222452
Representative plantOGRP1715800
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G27410.21e-129NAC family protein
Publications ? help Back to Top
  1. Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD
    Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments.
    Theor. Appl. Genet., 2005. 112(1): p. 72-84
    [PMID:16208505]
  2. Ouyang B, et al.
    Identification of early salt stress response genes in tomato root by suppression subtractive hybridization and microarray analysis.
    J. Exp. Bot., 2007. 58(3): p. 507-20
    [PMID:17210988]
  3. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  4. Du M, et al.
    Closely related NAC transcription factors of tomato differentially regulate stomatal closure and reopening during pathogen attack.
    Plant Cell, 2014. 26(7): p. 3167-84
    [PMID:25005917]
  5. Du M, et al.
    MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato.
    Plant Cell, 2017. 29(8): p. 1883-1906
    [PMID:28733419]
  6. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]