PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Solyc06g073720.1.1
Common NameEIL1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon
Family EIL
Protein Properties Length: 611aa    MW: 69481.5 Da    PI: 6.1761
Description EIL family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Solyc06g073720.1.1genomeITAGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN3502.71.8e-153514281353
                         XXXXXXXXXXXXXXXXXXXXXXX..XXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
                EIN3   1 eelkkrmwkdqmllkrlkerkkqlledkeaatgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpvegasdsL 91 
                         +el++rmw+d+m+lkrlke++k+    ke  ++ +k+++s+eqarrkkmsraQDgiLkYMlk+mevc+aqGfvYgiipekgkpv+gasd+L
  Solyc06g073720.1.1  51 DELERRMWRDKMKLKRLKEMSKS----KEG-VDPAKQRQSQEQARRKKMSRAQDGILKYMLKMMEVCKAQGFVYGIIPEKGKPVSGASDNL 136
                         79*******************98....677.8999******************************************************** PP

                         XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH---S--HHHH CS
                EIN3  92 raWWkekvefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWWPtGkelwwg 182
                         r+WWk+kv+fdrngpaai+kyqa+++i++ +++++     ++h+l+elqDTtlgSLLsalmqhcdppqrrfplekgv+pPWWPtGke+ww+
  Solyc06g073720.1.1 137 REWWKDKVRFDRNGPAAIAKYQADHAIPGMNEGSNP-VGPTPHTLQELQDTTLGSLLSALMQHCDPPQRRFPLEKGVPPPWWPTGKEDWWP 226
                         **********************************87.99**************************************************** PP

                         HHT--TT--.-----GGG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXXX..XX.XXXXX CS
                EIN3 183 elglskdqgtppykkphdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsah..ss.slrkq 270
                         +lgl+kdqg  pykkphdlkkawkv+vLtavikhm p+i++ir+l+rqsk+lqdkm+akes+++l++++qee+++++++++  ++ s+   
  Solyc06g073720.1.1 227 QLGLQKDQGSLPYKKPHDLKKAWKVGVLTAVIKHMFPDIAKIRKLVRQSKCLQDKMTAKESATWLAIISQEEALARELYPDrcPPlSSAGV 317
                         *********************************************************************************8633566779 PP

                         XXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX..............................XXXXXXXXXXXXXXXXXXXXX......XX CS
                EIN3 271 spkvtlsceqkedvegkkeskikhvqavktta..............................gfpvvrkrkkkpsesakvsskevsrtcqs 331
                         s ++ l++++++dveg +++   +v+++k ++                              ++++  krk +  e++ ++++++ +tc+ 
  Solyc06g073720.1.1 318 SGNFMLNDSSEYDVEGAQDEPNFDVHEQKPNHlnllnisaerfketmplqqqshpnkdelvtNLDFSLKRK-QANEPTVMMDQKI-YTCEF 406
                         ***************777777799999999999*****************************999*****9.7888899988876.***** PP

                         XXXXX.XXXXXXXXXXXXXXXX CS
                EIN3 332 sqfrgsetelifadknsisqne 353
                          q++++e +++f+d++s+++++
  Solyc06g073720.1.1 407 LQCPHNELRHGFQDRSSRDNHQ 428
                         ********************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048731.4E-12851298No hitNo description
Gene3DG3DSA:1.10.3180.103.0E-74172308IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamilySSF1167683.4E-60177301IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0071281Biological Processcellular response to iron ion
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 611 aa     Download sequence    Send to blast
MMMFEEMGFC GDLDFFPAPL KEVEVSAPQS QTEPDSVVDD DYSDEEEIEV DELERRMWRD  60
KMKLKRLKEM SKSKEGVDPA KQRQSQEQAR RKKMSRAQDG ILKYMLKMME VCKAQGFVYG  120
IIPEKGKPVS GASDNLREWW KDKVRFDRNG PAAIAKYQAD HAIPGMNEGS NPVGPTPHTL  180
QELQDTTLGS LLSALMQHCD PPQRRFPLEK GVPPPWWPTG KEDWWPQLGL QKDQGSLPYK  240
KPHDLKKAWK VGVLTAVIKH MFPDIAKIRK LVRQSKCLQD KMTAKESATW LAIISQEEAL  300
ARELYPDRCP PLSSAGVSGN FMLNDSSEYD VEGAQDEPNF DVHEQKPNHL NLLNISAERF  360
KETMPLQQQS HPNKDELVTN LDFSLKRKQA NEPTVMMDQK IYTCEFLQCP HNELRHGFQD  420
RSSRDNHQFA CLYRSSTCFG VSNFQINEVK PVVFPQQYVQ PKSSALPVNQ GPPSFDLSGI  480
GVPEDGQRMI NELMSIYDSD VQGSKRQNRG NIALTKEQPH QQPRVHQDNY LLSQGIMDGN  540
IFKNTNISTT QSMLPQVDPF DQSKAFNAGS NDNFHFMFGS PFNIQSTNYN GNLPSIGYDT  600
TPKQDAPIWY *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4zds_A2e-851763072133Protein ETHYLENE INSENSITIVE 3
4zds_B2e-851763072133Protein ETHYLENE INSENSITIVE 3
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Les.34720.0callus| floral bud| flower| fruit| leaf| root| stem
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor acting as a positive regulator in the ethylene response pathway. Is required for ethylene responsiveness in adult plant tissues. Binds a primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter with consequence to activate the transcription of this gene. {ECO:0000269|PubMed:9215635, ECO:0000269|PubMed:9851977}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSolyc06g073720.1.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF3287840.0Lycopersicon esculentum EIL1 (EIL1) mRNA, complete cds
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001234541.10.0protein ETHYLENE INSENSITIVE 3-Like 1
SwissprotO246060.0EIN3_ARATH; Protein ETHYLENE INSENSITIVE 3
TrEMBLA0A3Q7H2D60.0A0A3Q7H2D6_SOLLC; Uncharacterized protein
STRINGSolyc06g073720.1.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA30423178
Representative plantOGRP5631682
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G20770.10.0EIL family protein
Publications ? help Back to Top
  1. Tieman DM,Ciardi JA,Taylor MG,Klee HJ
    Members of the tomato LeEIL (EIN3-like) gene family are functionally redundant and regulate ethylene responses throughout plant development.
    Plant J., 2001. 26(1): p. 47-58
    [PMID:11359609]
  2. Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD
    Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments.
    Theor. Appl. Genet., 2005. 112(1): p. 72-84
    [PMID:16208505]
  3. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  4. Luo J, et al.
    A DELLA gene, RhGAI1, is a direct target of EIN3 and mediates ethylene-regulated rose petal cell expansion via repressing the expression of RhCesA2.
    J. Exp. Bot., 2013. 64(16): p. 5075-84
    [PMID:24014864]
  5. Kim HG, et al.
    GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling.
    Plant Physiol., 2013. 163(4): p. 1776-91
    [PMID:24170202]
  6. Zhong S, et al.
    Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth.
    Proc. Natl. Acad. Sci. U.S.A., 2014. 111(11): p. 3913-20
    [PMID:24599595]
  7. Kim HG, et al.
    GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis.
    FEBS Lett., 2014. 588(9): p. 1652-8
    [PMID:24631536]
  8. Jourda C, et al.
    Expansion of banana (Musa acuminata) gene families involved in ethylene biosynthesis and signalling after lineage-specific whole-genome duplications.
    New Phytol., 2014. 202(3): p. 986-1000
    [PMID:24716518]
  9. Zhang GB,Yi HY,Gong JM
    The Arabidopsis ethylene/jasmonic acid-NRT signaling module coordinates nitrate reallocation and the trade-off between growth and environmental adaptation.
    Plant Cell, 2014. 26(10): p. 3984-98
    [PMID:25326291]
  10. Wang J, et al.
    Arabidopsis ROOT HAIR DEFECTIVE3 is involved in nitrogen starvation-induced anthocyanin accumulation.
    J Integr Plant Biol, 2015. 57(8): p. 708-21
    [PMID:25494721]
  11. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  12. Kazan K
    Diverse roles of jasmonates and ethylene in abiotic stress tolerance.
    Trends Plant Sci., 2015. 20(4): p. 219-29
    [PMID:25731753]
  13. Yang C, et al.
    MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
    Plant Physiol., 2015. 169(1): p. 148-65
    [PMID:25995326]
  14. Contreras-Cornejo HA, et al.
    Mitogen-Activated Protein Kinase 6 and Ethylene and Auxin Signaling Pathways Are Involved in Arabidopsis Root-System Architecture Alterations by Trichoderma atroviride.
    Mol. Plant Microbe Interact., 2015. 28(6): p. 701-10
    [PMID:26067203]
  15. Li J,Xu HH,Liu WC,Zhang XW,Lu YT
    Ethylene Inhibits Root Elongation during Alkaline Stress through AUXIN1 and Associated Changes in Auxin Accumulation.
    Plant Physiol., 2015. 168(4): p. 1777-91
    [PMID:26109425]
  16. Street IH, et al.
    Ethylene Inhibits Cell Proliferation of the Arabidopsis Root Meristem.
    Plant Physiol., 2015. 169(1): p. 338-50
    [PMID:26149574]
  17. Ju C,Chang C
    Mechanistic Insights in Ethylene Perception and Signal Transduction.
    Plant Physiol., 2015. 169(1): p. 85-95
    [PMID:26246449]
  18. Qing D, et al.
    Quantitative and Functional Phosphoproteomic Analysis Reveals that Ethylene Regulates Water Transport via the C-Terminal Phosphorylation of Aquaporin PIP2;1 in Arabidopsis.
    Mol Plant, 2016. 9(1): p. 158-174
    [PMID:26476206]
  19. Zhang Y,Liu J,Chai J,Xing D
    Mitogen-activated protein kinase 6 mediates nuclear translocation of ORE3 to promote ORE9 gene expression in methyl jasmonate-induced leaf senescence.
    J. Exp. Bot., 2016. 67(1): p. 83-94
    [PMID:26507893]
  20. Li X,Pan Y,Chang B,Wang Y,Tang Z
    NO Promotes Seed Germination and Seedling Growth Under High Salt May Depend on EIN3 Protein in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 1203
    [PMID:26779234]
  21. Yu Y, et al.
    Salt Stress and Ethylene Antagonistically Regulate Nucleocytoplasmic Partitioning of COP1 to Control Seed Germination.
    Plant Physiol., 2016. 170(4): p. 2340-50
    [PMID:26850275]
  22. Pelagio-Flores R,Ruiz-Herrera LF,López-Bucio J
    Serotonin modulates Arabidopsis root growth via changes in reactive oxygen species and jasmonic acid-ethylene signaling.
    Physiol Plant, 2016. 158(1): p. 92-105
    [PMID:26864878]
  23. Tao S, et al.
    The THO/TREX Complex Active in miRNA Biogenesis Negatively Regulates Root-Associated Acid Phosphatase Activity Induced by Phosphate Starvation.
    Plant Physiol., 2016. 171(4): p. 2841-53
    [PMID:27329222]
  24. Song L, et al.
    The Molecular Mechanism of Ethylene-Mediated Root Hair Development Induced by Phosphate Starvation.
    PLoS Genet., 2016. 12(7): p. e1006194
    [PMID:27427911]
  25. Jeong J, et al.
    Phytochrome and Ethylene Signaling Integration in Arabidopsis Occurs via the Transcriptional Regulation of Genes Co-targeted by PIFs and EIN3.
    Front Plant Sci, 2016. 7: p. 1055
    [PMID:27486469]
  26. Tsai KJ,Lin CY,Ting CY,Shih MC
    Ethylene-Regulated Glutamate Dehydrogenase Fine-Tunes Metabolism during Anoxia-Reoxygenation.
    Plant Physiol., 2016. 172(3): p. 1548-1562
    [PMID:27677986]
  27. Zhang F, et al.
    EIN2-dependent regulation of acetylation of histone H3K14 and non-canonical histone H3K23 in ethylene signalling.
    Nat Commun, 2016. 7: p. 13018
    [PMID:27694846]
  28. Liu G, et al.
    Local Transcriptional Control of YUCCA Regulates Auxin Promoted Root-Growth Inhibition in Response to Aluminium Stress in Arabidopsis.
    PLoS Genet., 2016. 12(10): p. e1006360
    [PMID:27716807]
  29. Shen X,Li Y,Pan Y,Zhong S
    Activation of HLS1 by Mechanical Stress via Ethylene-Stabilized EIN3 Is Crucial for Seedling Soil Emergence.
    Front Plant Sci, 2016. 7: p. 1571
    [PMID:27822221]
  30. Shi H, et al.
    The Red Light Receptor Phytochrome B Directly Enhances Substrate-E3 Ligase Interactions to Attenuate Ethylene Responses.
    Dev. Cell, 2016. 39(5): p. 597-610
    [PMID:27889482]
  31. Wawrzyńska A,Sirko A
    EIN3 interferes with the sulfur deficiency signaling in Arabidopsis thaliana through direct interaction with the SLIM1 transcription factor.
    Plant Sci., 2016. 253: p. 50-57
    [PMID:27968996]
  32. Zemlyanskaya EV,Levitsky VG,Oshchepkov DY,Grosse I,Mironova VV
    The Interplay of Chromatin Landscape and DNA-Binding Context Suggests Distinct Modes of EIN3 Regulation in Arabidopsis thaliana.
    Front Plant Sci, 2016. 7: p. 2044
    [PMID:28119721]
  33. He X,Jiang J,Wang CQ,Dehesh K
    ORA59 and EIN3 interaction couples jasmonate-ethylene synergistic action to antagonistic salicylic acid regulation of PDF expression.
    J Integr Plant Biol, 2017. 59(4): p. 275-287
    [PMID:28168848]
  34. Abozeid A, et al.
    Ethylene Improves Root System Development under Cadmium Stress by Modulating Superoxide Anion Concentration in Arabidopsis thaliana.
    Front Plant Sci, 2017. 8: p. 253
    [PMID:28286514]
  35. Quan R, et al.
    EIN3 and SOS2 synergistically modulate plant salt tolerance.
    Sci Rep, 2017. 7: p. 44637
    [PMID:28300216]
  36. Kim GD,Cho YH,Yoo SD
    Regulatory Functions of Cellular Energy Sensor SNF1-Related Kinase1 for Leaf Senescence Delay through ETHYLENE- INSENSITIVE3 Repression.
    Sci Rep, 2017. 7(1): p. 3193
    [PMID:28600557]
  37. Liu Y, et al.
    Light and Ethylene Coordinately Regulate the Phosphate Starvation Response through Transcriptional Regulation of PHOSPHATE STARVATION RESPONSE1.
    Plant Cell, 2017. 29(9): p. 2269-2284
    [PMID:28842534]
  38. Liu X,Li Y,Zhong S
    Interplay between Light and Plant Hormones in the Control of Arabidopsis Seedling Chlorophyll Biosynthesis.
    Front Plant Sci, 2017. 8: p. 1433
    [PMID:28861105]
  39. Zhang F, et al.
    EIN2 mediates direct regulation of histone acetylation in the ethylene response.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(38): p. 10274-10279
    [PMID:28874528]
  40. Yan Z, et al.
    Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1.
    Plant Physiol., 2017. 175(3): p. 1438-1454
    [PMID:28931628]
  41. Liu X, et al.
    EIN3 and PIF3 Form an Interdependent Module That Represses Chloroplast Development in Buried Seedlings.
    Plant Cell, 2017. 29(12): p. 3051-3067
    [PMID:29114016]
  42. Feng Y, et al.
    Ethylene promotes root hair growth through coordinated EIN3/EIL1 and RHD6/RSL1 activity in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(52): p. 13834-13839
    [PMID:29233944]
  43. Harkey AF, et al.
    Identification of Transcriptional and Receptor Networks That Control Root Responses to Ethylene.
    Plant Physiol., 2018. 176(3): p. 2095-2118
    [PMID:29259106]
  44. Zhang F,Wang L,Ko EE,Shao K,Qiao H
    Histone Deacetylases SRT1 and SRT2 Interact with ENAP1 to Mediate Ethylene-Induced Transcriptional Repression.
    Plant Cell, 2018. 30(1): p. 153-166
    [PMID:29298835]
  45. Lv B, et al.
    Brassinosteroids regulate root growth by controlling reactive oxygen species homeostasis and dual effect on ethylene synthesis in Arabidopsis.
    PLoS Genet., 2018. 14(1): p. e1007144
    [PMID:29324765]
  46. Dou L,He K,Higaki T,Wang X,Mao T
    Ethylene Signaling Modulates Cortical Microtubule Reassembly in Response to Salt Stress.
    Plant Physiol., 2018. 176(3): p. 2071-2081
    [PMID:29431630]
  47. Meng LS,Xu MK,Wan W,Wang JY
    Integration of Environmental and Developmental (or Metabolic) Control of Seed Mass by Sugar and Ethylene Metabolisms in Arabidopsis.
    J. Agric. Food Chem., 2018. 66(13): p. 3477-3488
    [PMID:29528636]
  48. Munné-Bosch S,Simancas B,Müller M
    Ethylene signaling cross-talk with other hormones in Arabidopsis thaliana exposed to contrasting phosphate availability: Differential effects in roots, leaves and fruits.
    J. Plant Physiol., 2018. 226: p. 114-122
    [PMID:29758376]