PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Solyc05g051200.1.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon
Family ERF
Protein Properties Length: 225aa    MW: 25528.5 Da    PI: 5.1924
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Solyc05g051200.1.1genomeITAGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP260.24.9e-1996146255
                 AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                         +y GVr ++ +g++++eIrd + ng   r++lg+f+taeeAa a+++a+++++g
  Solyc05g051200.1.1  96 HYIGVRKRP-WGKYASEIRDSTRNG--IRVWLGTFDTAEEAALAYDQAALSMRG 146
                         799******.**********44465..*************************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000188.00E-2895154No hitNo description
SMARTSM003801.4E-3296160IPR001471AP2/ERF domain
PROSITE profilePS5103221.45696154IPR001471AP2/ERF domain
SuperFamilySSF541717.85E-2296156IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.109.1E-2996155IPR001471AP2/ERF domain
PfamPF008476.3E-1396146IPR001471AP2/ERF domain
PRINTSPR003677.6E-1097108IPR001471AP2/ERF domain
PRINTSPR003677.6E-10120136IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 225 aa     Download sequence    Send to blast
MSSPLEIDTS FSHSNLLFLE DESSWSNTHD PFVDIDEYLP IIIPCNDEEI VVESSNTSTT  60
TTTTTTSKVA SIQNIHHDQE EVTSIEKKHE DDQEKHYIGV RKRPWGKYAS EIRDSTRNGI  120
RVWLGTFDTA EEAALAYDQA ALSMRGPWSL LNFPMEHVKK SLENIEYSCK DGLSPAAVLK  180
ATHKTRRVKH KRSSRKKKNE NLENVFVFQD LGVELLEELL MTSS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A9e-2995155161ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A1e-2895155464ATERF1
3gcc_A1e-2895155464ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Les.36790.0callus| fruit| leaf
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Ubiquitously expressed, mostly in flowers and rosettes after ethylene treatment. {ECO:0000269|PubMed:11950980}.
Functional Description ? help Back to Top
Source Description
UniProtActs as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression during the plant development, and/or mediated by stress factors and by components of stress signal transduction pathways. Seems to be a key integrator of ethylene and jasmonate signals in the regulation of ethylene/jasmonate-dependent defenses. Can mediate resistance to necrotizing fungi (Botrytis cinerea and Plectosphaerella cucumerina) and to soil borne fungi (Fusarium oxysporum conglutinans and Fusiarium oxysporum lycopersici), but probably not to necrotizing bacteria (Pseudomonas syringae tomato). {ECO:0000269|PubMed:11950980, ECO:0000269|PubMed:12060224, ECO:0000269|PubMed:12509529, ECO:0000269|PubMed:15242170, ECO:0000269|PubMed:9851977}.
Function -- GeneRIF ? help Back to Top
  1. TERF1 is a multifunctional ERF protein that can integrate different stress signal pathways
    [PMID: 15871029]
  2. The transgenic plants were growing vigorously, had dark green leaves and showed no symptoms of salt damage implying that the JERFs gene enhanced their salt tolerance.
    [PMID: 19203952]
  3. these findings suggest that TERF1 is an ethylene inducible factor regulating reactive oxygen species scavenging during stress responses.
    [PMID: 27435661]
Cis-element ? help Back to Top
SourceLink
PlantRegMapSolyc05g051200.1.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Ethylene induction is completely dependent on functional ETHYLENE-INSENSITIVE2 (EIN2), ETHYLENE-INSENSITIVE3 (EIN3), which is itself a transcription factor and CORONATIVE-INSENSITIVE1 (COI1) proteins. Induction by jasmonate, B.cinerea or F.oxysporum as well as the synergistic induction by ethylene and jasmonate requires EIN2 and COI1. Induction by methyl jasmonate (MeJA) is independent of JAR1. Induction by salicylic acid (SA) is dependent on NPR1 but not on PAD4. Seems not to be induced by Alternaria brassicicola. {ECO:0000269|PubMed:11950980, ECO:0000269|PubMed:12060224, ECO:0000269|PubMed:12509529, ECO:0000269|PubMed:12805630, ECO:0000269|PubMed:15242170, ECO:0000269|PubMed:9851977}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0442360.0Lycopersicon esculentum ethylene-responsive factor 1 (ERF1) mRNA, complete cds
GenBankEU3956340.0Solanum lycopersicum ethylene response factor (ERF1) gene, promoter region and complete cds
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001234841.21e-167ethylene-responsive transcription factor 1
SwissprotQ8LDC83e-48ERF92_ARATH; Ethylene-responsive transcription factor 1B
TrEMBLA0A3Q7GNC21e-165A0A3Q7GNC2_SOLLC; Uncharacterized protein
STRINGSolyc05g051200.1.11e-166(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA21241165
Representative plantOGRP6161718
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G23240.15e-34ethylene response factor 1
Publications ? help Back to Top
  1. Huang Z, et al.
    Tomato TERF1 modulates ethylene response and enhances osmotic stress tolerance by activating expression of downstream genes.
    FEBS Lett., 2004. 573(1-3): p. 110-6
    [PMID:15327984]
  2. Zhang X, et al.
    Expressing TERF1 in tobacco enhances drought tolerance and abscisic acid sensitivity during seedling development.
    Planta, 2005. 222(3): p. 494-501
    [PMID:15871029]
  3. Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD
    Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments.
    Theor. Appl. Genet., 2005. 112(1): p. 72-84
    [PMID:16208505]
  4. Zarate SI,Kempema LA,Walling LL
    Silverleaf whitefly induces salicylic acid defenses and suppresses effectual jasmonic acid defenses.
    Plant Physiol., 2007. 143(2): p. 866-75
    [PMID:17189328]
  5. Li Y, et al.
    Expression of jasmonic ethylene responsive factor gene in transgenic poplar tree leads to increased salt tolerance.
    Tree Physiol., 2009. 29(2): p. 273-9
    [PMID:19203952]
  6. Vahabi K,Camehl I,Sherameti I,Oelm├╝ller R
    Growth of Arabidopsis seedlings on high fungal doses of Piriformospora indica has little effect on plant performance, stress, and defense gene expression in spite of elevated jasmonic acid and jasmonic acid-isoleucine levels in the roots.
    Plant Signal Behav, 2013. 8(11): p. e26301
    [PMID:24047645]
  7. Kim HG, et al.
    GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling.
    Plant Physiol., 2013. 163(4): p. 1776-91
    [PMID:24170202]
  8. Li J,Jia H,Wang J
    cGMP and ethylene are involved in maintaining ion homeostasis under salt stress in Arabidopsis roots.
    Plant Cell Rep., 2014. 33(3): p. 447-59
    [PMID:24306353]
  9. Zhong S, et al.
    Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth.
    Proc. Natl. Acad. Sci. U.S.A., 2014. 111(11): p. 3913-20
    [PMID:24599595]
  10. Kim HG, et al.
    GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis.
    FEBS Lett., 2014. 588(9): p. 1652-8
    [PMID:24631536]
  11. Schellingen K, et al.
    Cadmium-induced ethylene production and responses in Arabidopsis thaliana rely on ACS2 and ACS6 gene expression.
    BMC Plant Biol., 2014. 14: p. 214
    [PMID:25082369]
  12. Ellouzi H, et al.
    A comparative study of the early osmotic, ionic, redox and hormonal signaling response in leaves and roots of two halophytes and a glycophyte to salinity.
    Planta, 2014. 240(6): p. 1299-317
    [PMID:25156490]
  13. Nguyen AH, et al.
    Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress.
    Plant Cell Physiol., 2015. 56(9): p. 1762-72
    [PMID:26136597]
  14. Zhang H, et al.
    Ethylene Response Factor TERF1, Regulated by ETHYLENE-INSENSITIVE3-like Factors, Functions in Reactive Oxygen Species (ROS) Scavenging in Tobacco (Nicotiana tabacum L.).
    Sci Rep, 2016. 6: p. 29948
    [PMID:27435661]
  15. Cheng MC,Kuo WC,Wang YM,Chen HY,Lin TP
    UBC18 mediates ERF1 degradation under light-dark cycles.
    New Phytol., 2017. 213(3): p. 1156-1167
    [PMID:27787902]
  16. Timmermann T, et al.
    Paraburkholderia phytofirmans PsJN Protects Arabidopsis thaliana Against a Virulent Strain of Pseudomonas syringae Through the Activation of Induced Resistance.
    Mol. Plant Microbe Interact., 2017. 30(3): p. 215-230
    [PMID:28118091]
  17. Yu Y,Huang R
    Integration of Ethylene and Light Signaling Affects Hypocotyl Growth in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 57
    [PMID:28174592]
  18. Lestari R, et al.
    Overexpression of Hevea brasiliensis ethylene response factor HbERF-IXc5 enhances growth and tolerance to abiotic stress and affects laticifer differentiation.
    Plant Biotechnol. J., 2018. 16(1): p. 322-336
    [PMID:28626940]
  19. Dinolfo MI,Casta├▒ares E,Stenglein SA
    Resistance of Fusarium poae in Arabidopsis leaves requires mainly functional JA and ET signaling pathways.
    Fungal Biol, 2017. 121(10): p. 841-848
    [PMID:28889908]