PlantTFDB
Plant Transcription Factor Database
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Solyc04g077490.2.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum; Lycopersicon
Family AP2
Protein Properties Length: 653aa    MW: 71579.4 Da    PI: 7.4273
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Solyc04g077490.2.1genomeITAGView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2513.7e-16303362155
                 AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                         s+y+GV++++++gr++A+++d  ++  g  ++ ++++lg ++ +e+Aa+a++ a++k++g
  Solyc04g077490.2.1 303 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqtRKgRQVYLGGYDMEEKAARAYDLAALKYWG 362
                         78*******************988886678446*************************98 PP

2AP2461.3e-14405456155
                 AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                         s y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  Solyc04g077490.2.1 405 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAYDVAAIKFRG 456
                         57****************988532...5************************997 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000186.63E-22303370No hitNo description
SuperFamilySSF541711.11E-16303372IPR016177DNA-binding domain
PfamPF008478.9E-13303362IPR001471AP2/ERF domain
SMARTSM003803.8E-29304376IPR001471AP2/ERF domain
PROSITE profilePS5103219.203304370IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.104.6E-16304371IPR001471AP2/ERF domain
PRINTSPR003673.1E-6305316IPR001471AP2/ERF domain
CDDcd000186.02E-26405466No hitNo description
SuperFamilySSF541717.85E-18405466IPR016177DNA-binding domain
PfamPF008475.2E-10405456IPR001471AP2/ERF domain
PROSITE profilePS5103219.124406464IPR001471AP2/ERF domain
SMARTSM003801.1E-34406470IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.8E-18406464IPR001471AP2/ERF domain
PRINTSPR003673.1E-6446466IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 653 aa     Download sequence    Send to blast
MKSMNDDSRS SNNNISNNNS AAANTNWLGF SLTPHMKMEV TNSSDTQHQH QFAQSFYLSS  60
SPPPPMNVST TSALCYENNP FHSTLSVMPL KSDGSLCIME ALSRSHADAM VQSSSPKLED  120
FLGGASMGNS QYGSHDREAM ALSLDSLYYH QNEEEIQVHS HHPYYSPMHC HGMYHQETLL  180
EETKPTQISN CEAQMTGNEL KSWGQYAEQH AIDQHINATC SMVAAAAAAA SGGGGGTSGC  240
NELQSLSLSM NPGSQSSCVT PRQISPSGLE CVAVESKKRA SGKVAQKQPV HRKSIDTFGQ  300
RTSQYRGVTR HRWTGRYEAH LWDNSCKKEG QTRKGRQVYL GGYDMEEKAA RAYDLAALKY  360
WGPSTHINFP LENYQKELDD MKNMTRQEYV AHLRRKSSGF SRGASIYRGV TRHHQHGRWQ  420
ARIGRVAGNK DLYLGTFSTQ EEAAEAYDVA AIKFRGVNAV TNFDISRYDV EKIMASNTLP  480
AGELAKRTKE RESIEYNNNT GGVGGQKNEE CVDNNNNGTI TDWKMVLYQT SNPSLGSSYR  540
NPTSFSMALQ DLIGIDSMTN SNNHHHATIL DHEQNKIGNP FSNASSLVTS LGSSREASPD  600
KSATAASLVF AKPTKFAVPT ATSVNACIPS AQLRPIPVSM AHLPVFAALN DA*
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in floral primordia, in STM-negative region, then in sepal primordia. As sepal develops, progressively confined to a basal core before disappearing. Present in stamen primordia, then confined to a central region as they become stalked and develop locules. Later reduced to procambial cells as stamen mature. From petal primordia, expressed on the lateral edges of developing petals and finally confined to petal epidermis before disappearing. Present in carpel primordia, then in inner side of carpels especially in the placenta. Strong levels in ovules primordia and young ovules, then localized in integuments initiation zone before being confined to inner integument cells that will differentiate into the endothelium. Expressed in the distal half of the funiculus throughout ovule development and later extends into the chalaza. After fertilization, expression shift to the embryo. First on the apical part at the globular stage, then in cotyledons primordia, and later in cotyledons during the torpedo stage. As cotyledons grow out, expression becomes limited to a plane separating adaxial and abaxial parts. Excluded from the embryonic central region (ECR). In seedlings, found in leaf primordia then in central and lateral actively developing regions of extending leaves. {ECO:0000269|PubMed:10656774, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9671577}.
UniprotTISSUE SPECIFICITY: Mostly expressed in developing flowers. Also present in mature flowers, siliques and seedlings, but not in mature roots, leaves and stems. Expressed in ovules and in vegetative and floral primordia. {ECO:0000269|PubMed:15988559, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapSolyc04g077490.2.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001287930.10.0AP2-like ethylene-responsive transcription factor ANT-like
SwissprotQ389141e-163ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A060PVV00.0A0A060PVV0_SOLLC; AINTEGUMENTA homolog
STRINGSolyc04g077490.2.10.0(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA20742460
Representative plantOGRP11217209
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-163AP2 family protein
Publications ? help Back to Top
  1. Wang Y,van der Hoeven RS,Nielsen R,Mueller LA,Tanksley SD
    Characteristics of the tomato nuclear genome as determined by sequencing undermethylated EcoRI digested fragments.
    Theor. Appl. Genet., 2005. 112(1): p. 72-84
    [PMID:16208505]
  2. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  3. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  4. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  5. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  6. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  7. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  8. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  9. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  10. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  11. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  12. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]