PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676755576
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family bHLH
Protein Properties Length: 1183aa    MW: 134630 Da    PI: 7.9278
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676755576genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH26.71e-0861106354
                HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
        HLH   3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                ++h  +ErrRR riN  f++Lr++lP+++       +Ka +L ++v+Y ++L
  676755576  61 KKHRDAERRRRLRINCQFATLRTILPNLV------KDKAYVLGETVRYFNEL 106
                679************************83......57888888888888776 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474592.62E-952112IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS508889.79458106IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.1E-961111IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.0E-661106IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.8E-764112IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF546951.02E-8467572IPR011333SKP1/BTB/POZ domain
Gene3DG3DSA:3.30.710.108.4E-9468573No hitNo description
PROSITE profilePS500055.841677710IPR019734Tetratricopeptide repeat
SuperFamilySSF484526.58E-14679712IPR011990Tetratricopeptide-like helical domain
Gene3DG3DSA:1.25.40.102.1E-19679706IPR011990Tetratricopeptide-like helical domain
Gene3DG3DSA:1.25.40.102.1E-19769874IPR011990Tetratricopeptide-like helical domain
PROSITE profilePS500055.812806839IPR019734Tetratricopeptide repeat
SMARTSM000287.4806839IPR019734Tetratricopeptide repeat
SuperFamilySSF484526.58E-14808841IPR011990Tetratricopeptide-like helical domain
SuperFamilySSF484526.58E-149001035IPR011990Tetratricopeptide-like helical domain
SMARTSM00028120932965IPR019734Tetratricopeptide repeat
Gene3DG3DSA:1.25.40.102.1E-199341070IPR011990Tetratricopeptide-like helical domain
SuperFamilySSF484523.57E-139901173IPR011990Tetratricopeptide-like helical domain
SMARTSM000280.2810061039IPR019734Tetratricopeptide repeat
PROSITE profilePS500058.11310061039IPR019734Tetratricopeptide repeat
Gene3DG3DSA:1.25.40.102.1E-1010711178IPR011990Tetratricopeptide-like helical domain
PROSITE profilePS500056.81511021135IPR019734Tetratricopeptide repeat
SMARTSM000280.2211351168IPR019734Tetratricopeptide repeat
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 1183 aa     Download sequence    Send to blast
MVLLQHLEQR MSPISRCYNP TTYSTTMGRN FFPCATTSSK LFSKDFSAAK PKVESKEAAA  60
KKHRDAERRR RLRINCQFAT LRTILPNLVK DKAYVLGETV RYFNELKKMV KDIPTTPALE  120
DDFRLGYCNN KDLARVVFSC SDREGLMSEV AESIKAAKAK AVRAEIMTIG GRTKCALFIK  180
GVNGNEGLVR LKKSLKPLVN GDNESVPLSK TNNESWKLSV QSLQLLGFFL IDWLKMQPNL  240
FTAMRSLKFI EGCKGTHVYA LNPSSAPPPP PPIPTNAGGV GEKLLQHLQD HLRVNSIRSK  300
SSRTYQPPNR KNVVVSRDSL LPYGLPVTDQ LEPQIDPCLK FVDLIDKLAE IYRQIENCLE  360
FEKSDAYLEQ CAIFRGLSDP KLFRRSLRSA RQHAVNVHTK VVVASWLRYE RREDELIGTT  420
SIDCCGRNLE CPKATLVSGY DPESVYDHCV CSGAYVRSET SRDDDVSECS TSEVDYDMSF  480
CIGDDEVPCV RYKIASLSRP FKAMLYGGFR EMKRSVINFT HNGISVEGMR AAERFSRIQK  540
VEIFPPTIVL ELLRLANRFC CDELKSACDL HLARLVDNLD DAMLLMEYGL EEAAYLLVAA  600
CLQVFLRELP SSMHNSNVVK ILCSVEGRER LELVGHASFT LYLFLSHVAM EDDMISNTTV  660
MVLECLVECA VDTWQKQLAC HQLGVVMLER KEYKDAQRWF DYAVEAGHTY SLVGVARSKF  720
KRGHRYSAYK IMNSLISECS ATGWMHQERS MYCNGKEKLL DMDFATDLDP TLTFPYKFRA  780
VSLVEKSQFG AAVAELNKIM GFKVSPDCLE MRAWISIVME NYEGALKDIR ALLTLEPNFL  840
MFNKKIHGDH MVELLRPMVQ KWNQADCWMQ LYDRWSSVDD IGSLAVVHHM LAHDPWKSLL  900
RFRQSLLLLR LNCQKAAMRS LRLARNHSKS EHERLVYEGW ILYDTGHREE ALAKAEESIS  960
IQRSFEAYFL KAYVLADSTL DPESSKYVIQ LLEEALRCPS DGLRKGQALN NLGSVYVDCD  1020
KLDLAADCYM NALNIKHTRA HQGLARVYHL KNQRKAAYNE MTKLIKKAQN NASAFEKRSE  1080
YCDRDMAHGD LGMATQLDPL RTYPYRYRAA VLMDDRKESE AVEEISKAIA FKPDLQLLHL  1140
RAAFFDSMRE SADAIRDCEA ALSLDPSHTD TINLYHKARE PQS
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
16172KHRDAERRRRLR
Functional Description ? help Back to Top
Source Description
UniProtEssential regulator of the ethylene pathway, which acts by regulating the stability of 1-aminocyclopropane-1-carboxylate synthase (ACS) enzymes. May act as a substrate-specific adapter that connects ACS enzymes, such as ACS5, to ubiquitin ligase complexes, leading to proteasomal degradation of ACS enzymes. {ECO:0000269|PubMed:15118728, ECO:0000269|PubMed:16091151, ECO:0000269|PubMed:18808454}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676755576
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006411032.10.0ethylene-overproduction protein 1
SwissprotO650200.0ETO1_ARATH; Ethylene-overproduction protein 1
TrEMBLV4LPM60.0V4LPM6_EUTSA; Uncharacterized protein
STRINGXP_006411032.10.0(Eutrema salsugineum)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G38070.11e-91bHLH family protein
Publications ? help Back to Top
  1. Comella P, et al.
    Fine sequence analysis of 60 kb around the Arabidopsis thaliana AtEm1 locus on chromosome III.
    Plant Mol. Biol., 1999. 41(5): p. 687-700
    [PMID:10645728]
  2. Wang KL,Yoshida H,Lurin C,Ecker JR
    Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein.
    Nature, 2004. 428(6986): p. 945-50
    [PMID:15118728]
  3. Gingerich DJ, et al.
    Cullins 3a and 3b assemble with members of the broad complex/tramtrack/bric-a-brac (BTB) protein family to form essential ubiquitin-protein ligases (E3s) in Arabidopsis.
    J. Biol. Chem., 2005. 280(19): p. 18810-21
    [PMID:15749712]
  4. Yoshida H,Nagata M,Saito K,Wang KL,Ecker JR
    Arabidopsis ETO1 specifically interacts with and negatively regulates type 2 1-aminocyclopropane-1-carboxylate synthases.
    BMC Plant Biol., 2005. 5: p. 14
    [PMID:16091151]
  5. Christians MJ, et al.
    The BTB ubiquitin ligases ETO1, EOL1 and EOL2 act collectively to regulate ethylene biosynthesis in Arabidopsis by controlling type-2 ACC synthase levels.
    Plant J., 2009. 57(2): p. 332-45
    [PMID:18808454]
  6. Strader LC,Chen GL,Bartel B
    Ethylene directs auxin to control root cell expansion.
    Plant J., 2010. 64(5): p. 874-84
    [PMID:21105933]
  7. Wang L,Dong J,Gao Z,Liu D
    The Arabidopsis gene hypersensitive to phosphate starvation 3 encodes ethylene overproduction 1.
    Plant Cell Physiol., 2012. 53(6): p. 1093-105
    [PMID:22623414]
  8. Lockhart J
    Salt of the earth: ethylene promotes salt tolerance by enhancing Na/K homeostasis.
    Plant Cell, 2013. 25(9): p. 3150
    [PMID:24064767]
  9. Jiang C,Belfield EJ,Cao Y,Smith JA,Harberd NP
    An Arabidopsis soil-salinity-tolerance mutation confers ethylene-mediated enhancement of sodium/potassium homeostasis.
    Plant Cell, 2013. 25(9): p. 3535-52
    [PMID:24064768]
  10. Yoon GM,Kieber JJ
    ACC synthase and its cognate E3 ligase are inversely regulated by light.
    Plant Signal Behav, 2013. 8(12): p. e26478
    [PMID:24065059]
  11. Woeste KE,Ye C,Kieber JJ
    Two Arabidopsis mutants that overproduce ethylene are affected in the posttranscriptional regulation of 1-aminocyclopropane-1-carboxylic acid synthase.
    Plant Physiol., 1999. 119(2): p. 521-30
    [PMID:9952448]