PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676749138
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family WRKY
Protein Properties Length: 284aa    MW: 32535.4 Da    PI: 5.9373
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676749138genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY74.21.6e-2399160159
                ---SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS
       WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 
                ldDg++WrKYGqK+++g ++pr+YYrCt++   gC + k+v++s+++p + e++Y ++H+++
  676749138  99 LDDGHCWRKYGQKDIHGFKNPRGYYRCTHRftrGCLAVKQVQKSDTNPLCYEVKYVESHTCN 160
                59***************************9999***************************97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.2E-2288161IPR003657WRKY domain
PROSITE profilePS5081119.73894162IPR003657WRKY domain
SuperFamilySSF1182903.14E-2195161IPR003657WRKY domain
SMARTSM007741.6E-3099161IPR003657WRKY domain
PfamPF031066.7E-20100159IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 284 aa     Download sequence    Send to blast
MSMDEELVIK ELEQGRELAN QLMNNLQNPS SSTDSNKILI SGILRTYENT IAMMSLDKKT  60
LKRSPERIDQ SNRKRRMSEK KKTEKVTICV GTGQEGTSLD DGHCWRKYGQ KDIHGFKNPR  120
GYYRCTHRFT RGCLAVKQVQ KSDTNPLCYE VKYVESHTCN SIPSTTKYSV AVSEEEQKRV  180
TKLHDANRSD DTTIKSEELM FSLEDLDYKN EIFRTFSFSN PETDHHFLEW KDLMENISPT  240
TSESGITNEL LSTTISVANS PTDDSCFSSL ENFLVSSQDL SWMS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ir8_A4e-1898159768OsWRKY45
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the regulation of osmotic stress responses and stomatal movement (PubMed:24773321). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Positive regulator of EDS1-dependent defense against E.amylovora (PubMed:22316300). Together with WRKY70 and WRKY53, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2 (PubMed:22325892). Together with WRKY54 and WRKY70, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression (PubMed:28576847). {ECO:0000250, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:22325892, ECO:0000269|PubMed:24773321, ECO:0000269|PubMed:28576847}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676749138
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by drought, salt and hydrogen peroxide treatments (PubMed:24773321). Induced by salicylic acid (SA) (PubMed:22268143, PubMed:22325892). Up-regulated by E.amylovora (PubMed:22316300). Triggered by P.syringae (PubMed:22325892). {ECO:0000269|PubMed:22268143, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:22325892, ECO:0000269|PubMed:24773321}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013634303.11e-150PREDICTED: probable WRKY transcription factor 46 isoform X1
RefseqXP_013690571.11e-150probable WRKY transcription factor 46 isoform X2
SwissprotQ9SKD93e-97WRK46_ARATH; Probable WRKY transcription factor 46
TrEMBLA0A078I2Y51e-148A0A078I2Y5_BRANA; BnaC04g21660D protein
TrEMBLA0A3P6C4W31e-147A0A3P6C4W3_BRAOL; Uncharacterized protein
STRINGBo4g101290.11e-143(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM48882352
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G46400.11e-99WRKY DNA-binding protein 46
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Sheikh AH, et al.
    Regulation of WRKY46 Transcription Factor Function by Mitogen-Activated Protein Kinases in Arabidopsis thaliana.
    Front Plant Sci, 2016. 7: p. 61
    [PMID:26870073]
  3. Yan JY, et al.
    A WRKY Transcription Factor Regulates Fe Translocation under Fe Deficiency.
    Plant Physiol., 2016. 171(3): p. 2017-27
    [PMID:27208259]
  4. Chen J, et al.
    Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses.
    Plant Cell, 2017. 29(6): p. 1425-1439
    [PMID:28576847]
  5. Ma J, et al.
    Overexpression of TaWRKY146 Increases Drought Tolerance through Inducing Stomatal Closure in Arabidopsis thaliana.
    Front Plant Sci, 2017. 8: p. 2036
    [PMID:29225611]