PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676721930
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family bHLH
Protein Properties Length: 604aa    MW: 68910.6 Da    PI: 5.0549
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676721930genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH35.91.4e-11336387555
                HHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
        HLH   5 hnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                + ++ErrRR+++N+++  Lr+l+P+      + Kl+ a+iL  A++Y+k+Lq
  676721930 336 NLMAERRRRKKLNERLYALRSLVPTiTKFFWAWKLDRASILGDAINYVKELQ 387
                5589*********************774445789*****************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.7E-1828168IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474594.58E-17329400IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000833.46E-13330389No hitNo description
PROSITE profilePS5088815.993331386IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.3E-9336387IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003536.3E-13337392IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.2E-16338400IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009555Biological Processpollen development
GO:0048657Biological Processanther wall tapetum cell differentiation
GO:0005634Cellular Componentnucleus
GO:0000978Molecular FunctionRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 604 aa     Download sequence    Send to blast
MHNLNGNEEK LSQQSHFERM ESSSMQNLSE KLRPLVGARA WDYCVLWRLN EDQRFVKWMG  60
CCCGGTQLIE ENGTEEFSFG GCRDVMFHHP RTKSCEFLAH LPSSIPLDSG IYAETLLTNQ  120
TGWLSESSEP GFMQETICTR VLIPVPGGLV ELFATRHVAE DQNVVDFVMG HCNMLMDETV  180
TINMMTADEV ESKPYGMLSG EVHQKGSKDE EIMNLTSPYD ISADQIRLNF LPQMSDYEAQ  240
QQLKMRSDYH HQALGYLPEN GNKEMMGMNP FNTVAEEGMP VMGEPSLLVN EQQVANDKET  300
NENGRLDTAS DCSDQIDDED DPKYKKKSGK QSQAKNLMAE RRRRKKLNER LYALRSLVPT  360
ITKFFWAWKL DRASILGDAI NYVKELQNEA KELQDELEEN SETEDGSNRQ QQGGMSLNGT  420
VVTGFHPGLS CNSNVPNLKQ DVDLENSNDK GQEMEGFQPQ VDVAQLDGRE FFVKVICEYK  480
PGGFTRLMEA LDSLGLEVTN ANTTRFLSLV SNVFKVEKND SEMVPAEHVR NSLLEITRNT  540
SRGWHDDQMA TGSMQNEKNE VDYQHYDDHH HHGGHHHLHD HQMNQSAHHH HHQHHQHINH  600
YQNQ
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1324345KKKSGKQSQAKNLMAERRRRKK
2339346ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a crucial role in tapetum development. Required for male fertility and pollen differentiation, especially during the post-meiotic transcriptional regulation of microspore development within the developing anther (PubMed:12535353). Binds E-box regions in the AHL16/TEK promoter. {ECO:0000269|PubMed:12535353, ECO:0000269|PubMed:24804694}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676721930
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ5119910.0AJ511991.1 Brassica napus mRNA for bHLH transcription factor.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006409372.10.0transcription factor ABORTED MICROSPORES
SwissprotQ9ZVX20.0AMS_ARATH; Transcription factor ABORTED MICROSPORES
TrEMBLV4LJU20.0V4LJU2_EUTSA; Uncharacterized protein
STRINGXP_006409372.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM75892741
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G16910.10.0bHLH family protein
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Jiang J,Zhang Z,Cao J
    Pollen wall development: the associated enzymes and metabolic pathways.
    Plant Biol (Stuttg), 2013. 15(2): p. 249-63
    [PMID:23252839]
  3. Xu J, et al.
    ABORTED MICROSPORES Acts as a Master Regulator of Pollen Wall Formation in Arabidopsis.
    Plant Cell, 2014. 26(4): p. 1544-1556
    [PMID:24781116]
  4. Qian H, et al.
    Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in Arabidopsis thaliana: IM-induced inhibition of key genes regulating anther and pollen biosynthesis.
    Ecotoxicology, 2015. 24(1): p. 163-71
    [PMID:25348600]
  5. Xiong SX, et al.
    The transcription factors MS188 and AMS form a complex to activate the expression of CYP703A2 for sporopollenin biosynthesis in Arabidopsis thaliana.
    Plant J., 2016. 88(6): p. 936-946
    [PMID:27460657]
  6. Ferguson AC, et al.
    Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis.
    New Phytol., 2017. 213(2): p. 778-790
    [PMID:27787905]
  7. Lou Y, et al.
    Positive regulation of AMS by TDF1 and the formation of a TDF1-AMS complex are required for anther development in Arabidopsis thaliana.
    New Phytol., 2018. 217(1): p. 378-391
    [PMID:28940573]
  8. Bi H,Fan W,Zhang P
    C4 Protein of Sweet Potato Leaf Curl Virus Regulates Brassinosteroid Signaling Pathway through Interaction with AtBIN2 and Affects Male Fertility in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1689
    [PMID:29021807]