PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676709604
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family ERF
Protein Properties Length: 391aa    MW: 43436.8 Da    PI: 4.5388
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676709604genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP261.22.4e-19128178256
        AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkklege 56 
                +y+G+r+++ +g+W+AeIrdp++     r +lg+f+taeeAa+a++ a+++++g+
  676709604 128 QYRGIRQRP-WGKWAAEIRDPRK---GSREWLGTFDTAEEAARAYDSAARRIRGN 178
                69*******.**********954...39************************985 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003802.1E-38128191IPR001471AP2/ERF domain
PROSITE profilePS5103224.355128185IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.9E-32128186IPR001471AP2/ERF domain
CDDcd000188.53E-33128186No hitNo description
SuperFamilySSF541713.73E-22128186IPR016177DNA-binding domain
PfamPF008471.6E-12129177IPR001471AP2/ERF domain
PRINTSPR003673.4E-11129140IPR001471AP2/ERF domain
PRINTSPR003673.4E-11151167IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001666Biological Processresponse to hypoxia
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 391 aa     Download sequence    Send to blast
MCGGAIISDF IPPPISRRVT SEFIWPDLRK ASKKRSKKRS DFFDLDDEFE ADFQGFKDDD  60
DAAFDCEDEF DVDDDVFVNV KPFVFTAATK PVASPPTAFA STGSVSGKKT VESGGQAEKS  120
VKRKRKNQYR GIRQRPWGKW AAEIRDPRKG SREWLGTFDT AEEAARAYDS AARRIRGNKA  180
KVNFPEEMVP SVSQKRSSAK TSNLKKPVAK PNQSPALVQQ PTHLSQYCNN SFDNMGHDSF  240
GESSFMEEKP QMYNNQFGLT NSFDVGGNNG YQYFSSDQGS NSFDCSEFGW SDHGPKTPEI  300
SSMLVNNNQA PFTEETNAAK KLKPNSEDGT SNNDNSDDLM AYLDNALWES PLEVEAILGV  360
DAAAAAVTQE EENPMDLWSL DDINSMLDGV F
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A9e-22128185260ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
5wx9_A1e-211271871374Ethylene-responsive transcription factor ERF096
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in carotenoid biosynthesis regulation. Binds to the 5'-ATCTA-3' element present in the promoter of phytoene synthase (PSY) and phytoene desaturase (PDS). Involved in ethylene response and resistance to necrotrophic pathogens. Acts as a downstream regulator in the ethylene signaling pathway. Partially redundant with RAP2-12. {ECO:0000269|PubMed:17873090, ECO:0000269|PubMed:20357136, ECO:0000269|PubMed:22530619}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676709604
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by darkness, ethylene and Botrytis cinerea. {ECO:0000269|PubMed:20357136, ECO:0000269|PubMed:22530619}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3525200.0AK352520.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-01-B04.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006297883.10.0ethylene-responsive transcription factor RAP2-2
SwissprotQ9LUM40.0RAP22_ARATH; Ethylene-responsive transcription factor RAP2-2
TrEMBLR0G5V10.0R0G5V1_9BRAS; Uncharacterized protein
STRINGCagra.1582s0005.1.p0.0(Capsella grandiflora)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM10281650
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G14230.31e-178related to AP2 2
Publications ? help Back to Top
  1. Haas BJ, et al.
    Full-length messenger RNA sequences greatly improve genome annotation.
    Genome Biol., 2002. 3(6): p. RESEARCH0029
    [PMID:12093376]
  2. Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F
    Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana.
    Plant Sci., 2015. 236: p. 37-43
    [PMID:26025519]
  3. Gasch P, et al.
    Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    Plant Cell, 2016. 28(1): p. 160-80
    [PMID:26668304]
  4. Yao Y, et al.
    ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis.
    New Phytol., 2017. 213(4): p. 1667-1681
    [PMID:28164334]
  5. Giuntoli B, et al.
    Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana.
    Plant Cell Environ., 2017. 40(10): p. 2333-2346
    [PMID:28741696]