PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_011088951.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum
Family E2F/DP
Protein Properties Length: 431aa    MW: 47792.9 Da    PI: 4.5484
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_011088951.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP83.81.4e-26117182171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL+llt++f++l++ +e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  XP_011088951.1 117 RYDSSLGLLTKRFINLIKLAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 182
                     6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.9E-28115183IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467859.52E-17117180IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.9E-33117182IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.9E-24119182IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146604.03E-46193299No hitNo description
SuperFamilySSF1440745.75E-33195299No hitNo description
PfamPF164212.5E-32198297IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 431 aa     Download sequence    Send to blast
MRQQTSRKHL SFASMKPPFG GGGVGVDYHE FPAADRKPNR VLEEAVFVKT PPLKQKSEMA  60
QCEAASAQRN MGPGNAGVMK GLPRTPVSGK AQKVPRTTKA NIGSPIGNNL TLVGNCRYDS  120
SLGLLTKRFI NLIKLAEDGI LDLNKAADTL EVQKRRIYDI TNVLEGIGLI EKKLKNRIQW  180
KGVDVLKPGE DDDSLSALQD EIENLNMEEH RLDECIREMQ EKLRGLSEDE NNQKWLFVTE  240
EDIKNLPCFQ NETLIAIKAP HGTTLEVPYP NESVDYPQRR FGIVLRSTMG PIDVYLVSQF  300
EEIKEAQPNV FEASSRDENA FAPASMEETT GNEIDIQGIE TQRMCSDAST SEDFVSGLMK  360
IIPDVDRDAD YWLLTDADVS ITDMWSIEPG VDWNNLNTLH EDYAIAGIST PQPPAPLPST  420
MPTPSVSNTG S
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A7e-25116183674PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_011088951.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011088951.10.0transcription factor E2FB
RefseqXP_011088952.10.0transcription factor E2FB
SwissprotQ9FV711e-136E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A2R6P7350.0A0A2R6P735_ACTCH; Transcription factor E2FB like
STRINGMigut.N02463.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10772484
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.21e-138E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]