PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_011086973.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum
Family HD-ZIP
Protein Properties Length: 727aa    MW: 79851.4 Da    PI: 6.3457
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_011086973.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox63.33.7e-203085156
                    TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
        Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                    +++ +++t++q+++Le++F+++++p++++r +L+++l+L  rq+k+WFqNrR+++k
  XP_011086973.1 30 KKRYHRHTAHQIQRLEAMFKECPHPDEKTRNQLSRELNLHPRQIKFWFQNRRTQMK 85
                    678899***********************************************998 PP

2START175.92.5e-552314552206
                     HHHHHHHHHHHHHHHC-TT-EEEE...EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkss...esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetle 83 
                     +a  a++el+++ +++ep+W ks+   e +n + + + f++ ++       ++ea+r+sgvv+m+   lve ++d + +W e ++    +a t+e
  XP_011086973.1 231 IAANAMDELIRLLQSDEPLWIKSAdgrETLNLESYQRMFQSPNShlknpnIRIEASRDSGVVIMNGLALVEMFMDAN-KWVELFPtivsRARTME 324
                     67889*******************996555555555555444448999999**************************.******99999****** PP

                     EECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE CS
           START  84 vissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvd 171
                     vissg      g+l lm+ elq+ls lvp R  +f+R+++q ++g+w+ivdvS d + + ++ ss+ +a +lpSg+li++++ng+skvtwveh++
  XP_011086973.1 325 VISSGmlgnqsGTLLLMYEELQVLSALVPtRQLYFLRFCQQIEQGSWAIVDVSYDIPHQESQFSSSCKAYRLPSGCLIQDMPNGYSKVTWVEHWE 419
                     *******************************************************99999999999***************************** PP

                     --SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
           START 172 lkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                     ++++ p h l+r lv+sgla+ga +w++tlqr ce+
  XP_011086973.1 420 VEDKAPiHRLYRDLVHSGLAFGAERWLSTLQRICER 455
                     **********************************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466899.19E-211287IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.603.2E-231889IPR009057Homeodomain-like
PROSITE profilePS5007117.542787IPR001356Homeobox domain
SMARTSM003892.1E-192891IPR001356Homeobox domain
CDDcd000863.61E-192988No hitNo description
PfamPF000461.0E-173085IPR001356Homeobox domain
PROSITE patternPS0002706285IPR017970Homeobox, conserved site
PROSITE profilePS5084849.621221458IPR002913START domain
SuperFamilySSF559613.85E-35222456No hitNo description
CDDcd088751.84E-118225454No hitNo description
SMARTSM002341.1E-45230455IPR002913START domain
PfamPF018525.0E-47231455IPR002913START domain
Gene3DG3DSA:3.30.530.201.0E-4232440IPR023393START-like domain
SuperFamilySSF559614.21E-22477718No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 727 aa     Download sequence    Send to blast
MEFSSGGGGG GGGGSSGGDP GDGSDSHRRK KRYHRHTAHQ IQRLEAMFKE CPHPDEKTRN  60
QLSRELNLHP RQIKFWFQNR RTQMKAQHER ADNCALRAEN DKIRCENIAI REALKNVICP  120
SCGGPPVSED SYFDETKLRM ENAHLKEELD RVSSIAAKYI GRPISQLPPV QPIHVSSLDL  180
SMASFGGHGI PGPSLDLDLD LLPGSSSSVI PNLAFPPMSI SDMDKSLMAD IAANAMDELI  240
RLLQSDEPLW IKSADGRETL NLESYQRMFQ SPNSHLKNPN IRIEASRDSG VVIMNGLALV  300
EMFMDANKWV ELFPTIVSRA RTMEVISSGM LGNQSGTLLL MYEELQVLSA LVPTRQLYFL  360
RFCQQIEQGS WAIVDVSYDI PHQESQFSSS CKAYRLPSGC LIQDMPNGYS KVTWVEHWEV  420
EDKAPIHRLY RDLVHSGLAF GAERWLSTLQ RICERFACLL VTGNSTRDLG GVIPSLEGKR  480
SMMKLAERMV NNFCSSINPS NGQQWTTLSV LNEFEVRATL HKSTDPGQPN GVVLSAAATI  540
WLPIPPQIVF NFFRDERTRP QWDVLSNQNP VQEVAHIANG SHPGNCISVL RAFNTSQNNM  600
LILQESCIDS SGSLVVYCPV DLPAINIAMS GEDPSYIPLL PSGFTISPDG RPDHNQAGGV  660
TGGDGASTSS NTGIGGNSSG SLITVVFQIL VSNLPSARMS PESVTTVNNL IGNTVHQIKA  720
ALNCSTS
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1414SGGGGGGGGGS
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_011086973.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011086973.10.0homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A2Z7BLK00.0A0A2Z7BLK0_9LAMI; Uncharacterized protein
STRINGMigut.O00242.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]