PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_011077793.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Pedaliaceae; Sesamum
Family E2F/DP
Protein Properties Length: 471aa    MW: 52285.8 Da    PI: 4.8907
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_011077793.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.11.1e-26150215171
         E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                     r+++sL llt+kf++l++++e+g+++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  XP_011077793.1 150 RYDSSLSLLTKKFITLIKHAEDGELDLNKAADTL---QV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 215
                     6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.8E-28148217IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467858.94E-17150213IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.2E-33150215IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.5E-24152215IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440743.92E-32229332No hitNo description
PfamPF164217.9E-31231330IPR032198E2F transcription factor, CC-MB domain
CDDcd146603.99E-44231332No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 471 aa     Download sequence    Send to blast
MAGLGARTGD SGATPPAAAV SGQILSKQQT PPKMIGRHLA FASMKPPFVL PDDYHRFSTP  60
PRAAADHPPE AIIVKSTPLK RRNGYENNEV ESSEWSANLG YSDMVNSPFH SSKRRKDKGP  120
LKVMKNNRSV PSILVSNVDA PSPLTPGTCR YDSSLSLLTK KFITLIKHAE DGELDLNKAA  180
DTLQVQKRRI YDITNVLEGI GLIEKKLKNR IRWKGLDPSR PGKVDNDATL LQADIENLSV  240
EERSLDERIR QMQEKLRELS EDENNHKWVF VIEDDIKNLP CFQNETLIAV KAPHGTTLEV  300
PDPDEAVDYP QRRYRIILRS TMGPIDLYLV SQFEEKFEEV NGVEQSMNFS LAPSSGSNEN  360
PEMDRASIEH SPEQIEAQSQ ETHGLNSIVG ESTGGMTKII PSNIDNDADY WLLSDGDVSI  420
TDMWKTDSGL VWDGINMLDE ELEIAALGTA RPQTPPSGIA NLTPVVNFPP R
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-24146218276PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_011077793.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011077793.10.0transcription factor E2FA isoform X2
SwissprotQ9FNY01e-137E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A2Z7CQD60.0A0A2Z7CQD6_9LAMI; Uncharacterized protein
STRINGMigut.J00719.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10772484
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-142E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]