PlantTFDB
Plant Transcription Factor Database
PlantRegMap/PlantTFDB v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_18971.1_g00001.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family bHLH
Protein Properties Length: 195aa    MW: 21548.4 Da    PI: 6.7678
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_18971.1_g00001.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH59.36.5e-1964116155
                              CHHHHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                      HLH   1 rrrahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                              ++ +hn+ Er RR++iNs f+ Lr++lP+ +   +skKls ++++ +A eYI +Lq
  Rsa1.0_18971.1_g00001.1  64 KKLNHNASERGRRKKINSMFSALRSCLPStD---KSKKLSVSATVSQALEYIPELQ 116
                              6789*************************77...*******************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000835.32E-1763119No hitNo description
PROSITE profilePS5088815.11663115IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.7E-1664132IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.3E-1664116IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474597.59E-1964135IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.3E-1469121IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0010106Biological Processcellular response to iron ion starvation
GO:0055072Biological Processiron ion homeostasis
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 195 aa     Download sequence    Send to blast
MCALVPPLFP NFGWPCGDQG FYVNDDIANT FLDFPLPDLD VDHQNASSER HRTLGLVNNP  60
VLMKKLNHNA SERGRRKKIN SMFSALRSCL PSTDKSKKLS VSATVSQALE YIPELQEQVN  120
MLIKKKDELS FQISGQKDLL NTNQNGNPEK GDTRYASTVS ATRIGETGLM VQISSLQTVK  180
CSFGNLLSGI EEDGL
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in metal homeostasis. Confers tolerance to high zinc (Zn) and nickel (Ni). {ECO:0000269|PubMed:18088336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_18971.1_g00001.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up regulated by iron deficiency in roots and leaves, as well as by nickel, high zinc or high copper treatments. Repressed by heat treatment, high iron, low copper and low zinc treatments. {ECO:0000269|PubMed:12679534, ECO:0000269|PubMed:17516080, ECO:0000269|PubMed:18088336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018482009.11e-144PREDICTED: transcription factor bHLH100 isoform X1
SwissprotQ9ZVB51e-102BH100_ARATH; Transcription factor bHLH100
TrEMBLA0A078FR011e-127A0A078FR01_BRANA; BnaC04g47550D protein
STRINGBra016946.1-P1e-126(Brassica rapa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM48228153
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G41240.12e-94basic helix-loop-helix protein 100
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Maurer F,Naranjo Arcos MA,Bauer P
    Responses of a triple mutant defective in three iron deficiency-induced Basic Helix-Loop-Helix genes of the subgroup Ib(2) to iron deficiency and salicylic acid.
    PLoS ONE, 2014. 9(6): p. e99234
    [PMID:24919188]
  3. Martínez-Trujillo M, et al.
    Chromate alters root system architecture and activates expression of genes involved in iron homeostasis and signaling in Arabidopsis thaliana.
    Plant Mol. Biol., 2014. 86(1-2): p. 35-50
    [PMID:24928490]
  4. Van Dingenen J, et al.
    Strobilurins as growth-promoting compounds: how Stroby regulates Arabidopsis leaf growth.
    Plant Cell Environ., 2017. 40(9): p. 1748-1760
    [PMID:28444690]
  5. Wang C,Yao X,Yu D,Liang G
    Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana.
    Planta, 2017. 246(3): p. 421-431
    [PMID:28451750]
  6. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  7. Kailasam S,Wang Y,Lo JC,Chang HF,Yeh KC
    S-Nitrosoglutathione works downstream of nitric oxide to mediate iron-deficiency signaling in Arabidopsis.
    Plant J., 2018. 94(1): p. 157-168
    [PMID:29396986]
  8. Kurt F,Filiz E
    Genome-wide and comparative analysis of bHLH38, bHLH39, bHLH100 and bHLH101 genes in Arabidopsis, tomato, rice, soybean and maize: insights into iron (Fe) homeostasis.
    Biometals, 2018. 31(4): p. 489-504
    [PMID:29546482]