PlantTFDB
Plant Transcription Factor Database
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_03303.1_g00004.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family bZIP
Protein Properties Length: 305aa    MW: 33683.7 Da    PI: 4.3699
Description bZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_03303.1_g00004.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_129.51.6e-09148187443
                              XCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
                   bZIP_1   4 lkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNk 43 
                               k+  r+ +NR AA rsR+RKk+++  Le+k+k Le e  
  Rsa1.0_03303.1_g00004.1 148 AKKRTRRVRNRDAAVRSRERKKEYVTDLEKKSKYLERECI 187
                              69999******************************99865 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.20.5.1701.9E-12142207No hitNo description
SMARTSM003380.003143209IPR004827Basic-leucine zipper domain
PROSITE profilePS5021710.105147204IPR004827Basic-leucine zipper domain
SuperFamilySSF579594.25E-11149205No hitNo description
PfamPF077163.0E-8149189IPR004827Basic-leucine zipper domain
CDDcd147047.60E-19150201No hitNo description
PROSITE patternPS000360153167IPR004827Basic-leucine zipper domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010200Biological Processresponse to chitin
GO:0030968Biological Processendoplasmic reticulum unfolded protein response
GO:0005634Cellular Componentnucleus
GO:0005789Cellular Componentendoplasmic reticulum membrane
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 305 aa     Download sequence    Send to blast
MAEELGCVDF LGGDDDLFSD IDLSLFTETP IACDLIRSSP ESGNSWIGDI ESQLMNDEDN  60
QNFQELDQQS VSEFLADIFA DDPTSDSVDL VTGKVVPTEG FVNGKGPEGS DDAGKEKAVE  120
KKLNDSGSEN QDEAKVESEI SGDDDAMAKK RTRRVRNRDA AVRSRERKKE YVTDLEKKSK  180
YLERECIRLG RMLDCFVAEN HSLRLCLQKG SGGNASMMTR QESAVLLLES LLLGSLLWYL  240
GDIICPFLPL PQPETCFPPV EADGSENLVL SGLESNKLSN NYAGKSRRCK GSRPRMKHQV  300
CILVA
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Plays a role in plant immunity and abiotic stress responses. {ECO:0000269|PubMed:15781873, ECO:0000269|PubMed:18574595, ECO:0000269|PubMed:19017746, ECO:0000269|PubMed:21482766, ECO:0000269|PubMed:22359644}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00019PBMTransfer from AT1G42990Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_03303.1_g00004.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By tunicamycin, DTT and azetidine-2-carboxylate. Isoform 2 is induced by heat. {ECO:0000269|PubMed:15781873, ECO:0000269|PubMed:21482766}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0459642e-81AY045964.1 Arabidopsis thaliana putative bZIP transcription factor (At1g42990) mRNA, complete cds.
GenBankAY1338052e-81AY133805.1 Arabidopsis thaliana clone U10320 putative bZIP transcription factor (At1g42990) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018433928.10.0PREDICTED: bZIP transcription factor 60
SwissprotQ9C7S03e-73BZP60_ARATH; bZIP transcription factor 60
TrEMBLA0A3P6GEC11e-170A0A3P6GEC1_BRAOL; Uncharacterized protein
STRINGBo8g024280.11e-170(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM46342848
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G42990.11e-73basic region/leucine zipper motif 60
Publications ? help Back to Top
  1. Deng Y,Srivastava R,Howell SH
    Protein kinase and ribonuclease domains of IRE1 confer stress tolerance, vegetative growth, and reproductive development in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2013. 110(48): p. 19633-8
    [PMID:24145452]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Nagashima Y,Iwata Y,Ashida M,Mishiba K,Koizumi N
    Exogenous salicylic acid activates two signaling arms of the unfolded protein response in Arabidopsis.
    Plant Cell Physiol., 2014. 55(10): p. 1772-8
    [PMID:25138441]
  4. Parra-Rojas J,Moreno AA,Mitina I,Orellana A
    The dynamic of the splicing of bZIP60 and the proteins encoded by the spliced and unspliced mRNAs reveals some unique features during the activation of UPR in Arabidopsis thaliana.
    PLoS ONE, 2015. 10(4): p. e0122936
    [PMID:25860807]
  5. Zhang L,Chen H,Brandizzi F,Verchot J,Wang A
    The UPR branch IRE1-bZIP60 in plants plays an essential role in viral infection and is complementary to the only UPR pathway in yeast.
    PLoS Genet., 2015. 11(4): p. e1005164
    [PMID:25875739]
  6. Walley J, et al.
    Plastid-produced interorgannellar stress signal MEcPP potentiates induction of the unfolded protein response in endoplasmic reticulum.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(19): p. 6212-7
    [PMID:25922532]
  7. Ma ZX, et al.
    The THERMOSENSITIVE MALE STERILE 1 Interacts with the BiPs via DnaJ Domain and Stimulates Their ATPase Enzyme Activities in Arabidopsis.
    PLoS ONE, 2015. 10(7): p. e0132500
    [PMID:26186593]
  8. Sagor GH, et al.
    The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 687
    [PMID:26442007]
  9. Deng Y, et al.
    IRE1, a component of the unfolded protein response signaling pathway, protects pollen development in Arabidopsis from heat stress.
    Plant J., 2016. 88(2): p. 193-204
    [PMID:27304577]
  10. Gaguancela OA, et al.
    The IRE1/bZIP60 Pathway and Bax Inhibitor 1 Suppress Systemic Accumulation of Potyviruses and Potexviruses in Arabidopsis and Nicotiana benthamiana Plants.
    Mol. Plant Microbe Interact., 2016. 29(10): p. 750-766
    [PMID:27578623]
  11. Meng Z,Ruberti C,Gong Z,Brandizzi F
    CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses.
    Plant J., 2017. 89(3): p. 486-501
    [PMID:27747970]
  12. Wang B,Du H,Zhang Z,Xu W,Deng X
    BhbZIP60 from Resurrection Plant Boea hygrometrica Is an mRNA Splicing-Activated Endoplasmic Reticulum Stress Regulator Involved in Drought Tolerance.
    Front Plant Sci, 2017. 8: p. 245
    [PMID:28286511]
  13. Li Q, et al.
    Unfolded protein response activation compensates endoplasmic reticulum-associated degradation deficiency in Arabidopsis.
    J Integr Plant Biol, 2017. 59(7): p. 506-521
    [PMID:28418178]
  14. Zhang SS, et al.
    Tissue-Specific Transcriptomics Reveals an Important Role of the Unfolded Protein Response in Maintaining Fertility upon Heat Stress in Arabidopsis.
    Plant Cell, 2017. 29(5): p. 1007-1023
    [PMID:28442596]
  15. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  16. Ruberti C,Lai Y,Brandizzi F
    Recovery from temporary endoplasmic reticulum stress in plants relies on the tissue-specific and largely independent roles of bZIP28 and bZIP60, as well as an antagonizing function of BAX-Inhibitor 1 upon the pro-adaptive signaling mediated by bZIP28.
    Plant J., 2018. 93(1): p. 155-165
    [PMID:29124827]
  17. Kim JS,Yamaguchi-Shinozaki K,Shinozaki K
    ER-Anchored Transcription Factors bZIP17 and bZIP28 Regulate Root Elongation.
    Plant Physiol., 2018. 176(3): p. 2221-2230
    [PMID:29367234]