PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_00951.1_g00017.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family NAC
Protein Properties Length: 535aa    MW: 60203.2 Da    PI: 4.3067
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_00951.1_g00017.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM164.44.1e-51181461128
                      NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWk 84 
                              l+pGfrFhPtdeelv +yLk+k+ +k++++ ++i+ +++yk+ePwdLp + k+k+++ ewyfFs  d+ky++g+++nrat++gyWk
  Rsa1.0_00951.1_g00017.1  18 LAPGFRFHPTDEELVRYYLKRKICNKPFRF-DAISVTHVYKSEPWDLPsQsKLKSRDLEWYFFSVLDNKYSNGSKTNRATEKGYWK 102
                              579**************************9.99**************95247777888**************************** PP

                      NAM  85 atgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrl 128
                              +tgkd+e+ + ++ +vg+kktLv++kgrap+ge+++Wvmheyrl
  Rsa1.0_00951.1_g00017.1 103 TTGKDREIRNGSRVVVGMKKTLVYHKGRAPRGERSNWVMHEYRL 146
                              **********99999***************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019413.4E-5913169IPR003441NAC domain
PROSITE profilePS5100556.03818169IPR003441NAC domain
PfamPF023651.7E-2720146IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009819Biological Processdrought recovery
GO:0010150Biological Processleaf senescence
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000377Biological Processregulation of reactive oxygen species metabolic process
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0005886Cellular Componentplasma membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 535 aa     Download sequence    Send to blast
MGRGGGGSSS SSSETSSLAP GFRFHPTDEE LVRYYLKRKI CNKPFRFDAI SVTHVYKSEP  60
WDLPSQSKLK SRDLEWYFFS VLDNKYSNGS KTNRATEKGY WKTTGKDREI RNGSRVVVGM  120
KKTLVYHKGR APRGERSNWV MHEYRLVDDE IVKAGVQKDA YVVCKIFQKS GSGPKNGEQY  180
GAPFVEEEWE EEDGMTFVPN QDLEDQVYVD VNDNDIDQKL DVYDAIPIHL GFDHGESSNN  240
VETNYSDSTN YIEPGNYGYF EGPMEKHIIH DGSSLQNEEN GCGVQEESRA NLQSSDNIFD  300
ADASLYNDFP VESNYFTGEE FLDQNSSLLQ NDGLYLDAND LDNTQEDGFN FEDYLTFFDE  360
DDQNLTFDPS QLMGTEDNIP DQEELFQMAE TEAASGGKQV VEEASCSKQV HADATEFEPD  420
YKDTFIKKAS HMIGAIPSPT IFSSEILTKD GVVRLQAGQP SGSVHVSMIT ISDSNMDWSY  480
GKNGNLDLLL SFGLVQENVS GKSENHLTRV MLIFVCFWVL LLSVSFKVST LVSSR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3swm_A1e-421717519174NAC domain-containing protein 19
3swm_B1e-421717519174NAC domain-containing protein 19
3swm_C1e-421717519174NAC domain-containing protein 19
3swm_D1e-421717519174NAC domain-containing protein 19
3swp_A1e-421717519174NAC domain-containing protein 19
3swp_B1e-421717519174NAC domain-containing protein 19
3swp_C1e-421717519174NAC domain-containing protein 19
3swp_D1e-421717519174NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (Ref.6, PubMed:24323506, PubMed:25219309). Promotes reactive oxygen species (ROS) production during drought-induced leaf senescence. In response to abscisic acid (ABA)-mediated drought stress signals, binds directly to the promoters of RBOHC and RBOHE genes, encoding ROS biosynthetic enzymes, resulting in ROS accumulation and triggering leaf senescence via programmed cell death (PCD). ROS-induced leaf senescence sustains plant survival under drought conditions (PubMed:22313226). Involved in heat stress response. Modulates PCD through a ROS-mediated positive feedback control under heat stress conditions. This may provide an adaptation strategy for plant survival under extreme heat stress conditions (PubMed:25219309). Acts as repressor in preventing anther dehiscence during stamen development by suppressing genes that participate in jasmonic acid (JA) biosynthesis, such as DAD1, AOS, AOC3, OPR3 and 4CLL5/OPCL1 (PubMed:24323506). {ECO:0000269|PubMed:22313226, ECO:0000269|PubMed:24323506, ECO:0000269|PubMed:25219309, ECO:0000269|Ref.6}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00343DAPTransfer from AT3G10500Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_00951.1_g00017.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By abscisic acid (ABA) (PubMed:22313226, PubMed:25219309). Induced by heat shock (PubMed:25219309). Induced by cold, drought stress and methyl methanesulfonate (MMS) treatment (PubMed:17158162). {ECO:0000269|PubMed:17158162, ECO:0000269|PubMed:22313226, ECO:0000269|PubMed:25219309}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018439552.10.0PREDICTED: NAC domain-containing protein 53 isoform X2
SwissprotQ949N00.0NAC53_ARATH; NAC domain-containing protein 53
TrEMBLA0A078HVH30.0A0A078HVH3_BRANA; BnaA01g31650D protein
TrEMBLA0A3P5ZBD40.0A0A3P5ZBD4_BRACM; Uncharacterized protein
STRINGBo1g143830.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM31922762
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G10500.10.0NAC domain containing protein 53
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y
    Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress.
    Plant Cell, 2014. 26(12): p. 4656-79
    [PMID:25549671]
  4. Gladman NP,Marshall RS,Lee KH,Vierstra RD
    The Proteasome Stress Regulon Is Controlled by a Pair of NAC Transcription Factors in Arabidopsis.
    Plant Cell, 2016. 28(6): p. 1279-96
    [PMID:27194708]
  5. Sanz-Fernández M, et al.
    Screening Arabidopsis mutants in genes useful for phytoremediation.
    J. Hazard. Mater., 2017. 335: p. 143-151
    [PMID:28441590]