PlantTFDB
Plant Transcription Factor Database
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_00419.1_g00002.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family bHLH
Protein Properties Length: 185aa    MW: 20619.9 Da    PI: 8.6324
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_00419.1_g00002.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH38.42.3e-12749754
                             HHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS
                      HLH  7 erErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54
                             ++ErrRR+++N+++  Lr+++Pk +      K++ a+iL  Av+Y+k+L
  Rsa1.0_00419.1_g00002.1  7 MAERRRRKKLNDRLYMLRSVVPKiS------KMDRASILGDAVDYLKEL 49
                             89*********************66......****************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.993149IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.14E-16569IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000105.0E-10649IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.2E-14655IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.88E-12754No hitNo description
Gene3DG3DSA:4.10.280.104.5E-16763IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd048731.17E-8114174No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 185 aa     Download sequence    Send to blast
MPAKNLMAER RRRKKLNDRL YMLRSVVPKI SKMDRASILG DAVDYLKELL QRISDLHTEL  60
ESTPSSSSGL TLPSPQTLPY RVKEELCPSS SLPSPKGQQA RIEVNLREGK AVNIHMFCGR  120
RPGLLLSTMR ALDDLGLDVQ QAVISCFNGF ALDVFRAEQC QEGHEVLPEQ IKAVLLDTAG  180
YTGLL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A2e-14259663Transcription factor MYC2
5gnj_B2e-14259663Transcription factor MYC2
5gnj_E2e-14259663Transcription factor MYC2
5gnj_F2e-14259663Transcription factor MYC2
5gnj_G2e-14259663Transcription factor MYC2
5gnj_I2e-14259663Transcription factor MYC2
5gnj_M2e-14259663Transcription factor MYC2
5gnj_N2e-14259663Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1815ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtMediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269|PubMed:18641265, ECO:0000269|PubMed:28507175}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_00419.1_g00002.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1180111e-179AK118011.1 Arabidopsis thaliana At1g12860 mRNA for putative bHLH transcription factor (bHLH033), complete cds, clone: RAFL19-21-N13.
GenBankBT0053771e-179BT005377.1 Arabidopsis thaliana At1g12860 mRNA, complete cds.
GenBankEU3696701e-179EU369670.1 Arabidopsis thaliana bHLH protein (SCREAM2) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018451374.11e-131PREDICTED: transcription factor SCREAM2-like
SwissprotQ9LPW31e-118SCRM2_ARATH; Transcription factor SCREAM2
TrEMBLA0A1J3DY251e-120A0A1J3DY25_NOCCA; Transcription factor SCREAM2 (Fragment)
STRINGXP_006417184.11e-118(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM19522782
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G12860.11e-100bHLH family protein
Publications ? help Back to Top
  1. Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV
    The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity.
    Dokl. Biol. Sci., 2009.
    [PMID:19760875]
  2. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Emmerstorfer A, et al.
    Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris.
    Biotechnol J, 2015. 10(4): p. 623-35
    [PMID:25641738]
  5. Lee HG,Seo PJ
    The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis.
    Plant J., 2015. 82(6): p. 962-77
    [PMID:25912720]
  6. Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC
    Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31
    [PMID:27382177]
  7. Fu ZW,Wang YL,Lu YT,Yuan TT
    Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis.
    Plant Sci., 2016. 252: p. 282-289
    [PMID:27717464]
  8. de Marcos A, et al.
    A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development.
    Plant Physiol., 2017. 174(2): p. 823-842
    [PMID:28507175]