PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Rsa1.0_00191.1_g00036.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family bHLH
Protein Properties Length: 599aa    MW: 65357.4 Da    PI: 4.9934
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Rsa1.0_00191.1_g00036.1genomeRGDView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.51e-12428473454
                              HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
                      HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                              +h e+Er+RR+++N++f  Lr ++P+       K++Ka+ L  A+ YI++L
  Rsa1.0_00191.1_g00036.1 428 NHVEAERQRREKLNQRFYSLRAVVPNV-----SKMDKASLLGDAISYINEL 473
                              799***********************6.....5***************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.2E-5363258IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.282424473IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.31E-14427478No hitNo description
SuperFamilySSF474594.06E-18427498IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.5E-10428473IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.0E-18428494IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.5E-16430479IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006952Biological Processdefense response
GO:0009718Biological Processanthocyanin-containing compound biosynthetic process
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043425Molecular FunctionbHLH transcription factor binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 599 aa     Download sequence    Send to blast
MSSTDVQVTD HHLNQSTNGT NLWSTTEDDA SVMEPFIGSE HSSLWPQPPL TPPPPPHVTE  60
DTLQQRLQAL IEGARESWTY AVFWQLSHGF AGEDSTTAAA LLSWGDGYYK GEEEERKKRK  120
PNNPVSAAEQ EHRKRVIREL NSLISGGGGG TVSGSSSDEA GDEDVTDAEW FFLVSMTQSF  180
FASDGSGLPG RAFSNSQTIW LSGSNALAGS SCERARQGQV YGLETMVCVP TENGVVELGS  240
LEVIHQSSDL VDKVNGFFSF NGGGGGVSGS WAFNLNPDQG ENDPATTWIN EPDVTGIEPV  300
LGVNTGNNNN STSSNSDSQT ASKLCNGSSV EHPKQQQQHQ NPQISSSGFV EGDSKKKKRC  360
LVSDKEEEML SFTSVLPLAT KTNDSDHSDL EASVAKGQKS GGRTVVEPEK KPRKRGRKPA  420
NGREESLNHV EAERQRREKL NQRFYSLRAV VPNVSKMDKA SLLGDAISYI NELKAKLEKA  480
ECDKEELKKK IDGMSQEVAS GNVKSSVKDQ KCVDQDSGVS VEVEIDVKII GWDAMIRIQC  540
GKKNHPGAKF MEALRELELE VNHASLSVVN EFMIQQATVK MGNQFFTQDK LKAALMERV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rru_A1e-81252548227Transcription factor MYC3
4ywc_A1e-81252548227Transcription factor MYC3
4ywc_B1e-81252548227Transcription factor MYC3
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1409417KKPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in jasmonic acid (JA) gene regulation. With MYC2 and MYC3, controls additively subsets of JA-dependent responses. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the G-box (5'-CACGTG-3') of promoters. Activates multiple TIFY/JAZ promoters. {ECO:0000269|PubMed:21321051, ECO:0000269|PubMed:21335373, ECO:0000269|PubMed:23943862}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00086PBMTransfer from AT4G17880Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapRsa1.0_00191.1_g00036.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By UV treatment. Not induced by jasmonic acid. {ECO:0000269|PubMed:12679534, ECO:0000269|PubMed:21335373}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1834920.0AC183492.1 Brassica oleracea Contig G, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018471791.10.0PREDICTED: transcription factor MYC4
SwissprotO496870.0MYC4_ARATH; Transcription factor MYC4
TrEMBLA0A078I3920.0A0A078I392_BRANA; BnaC01g10420D protein
STRINGBo1g017990.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM12652896
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G17880.10.0bHLH family protein
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Chico JM, et al.
    Repression of Jasmonate-Dependent Defenses by Shade Involves Differential Regulation of Protein Stability of MYC Transcription Factors and Their JAZ Repressors in Arabidopsis.
    Plant Cell, 2014. 26(5): p. 1967-1980
    [PMID:24824488]
  3. Gasperini D, et al.
    Multilayered Organization of Jasmonate Signalling in the Regulation of Root Growth.
    PLoS Genet., 2015. 11(6): p. e1005300
    [PMID:26070206]
  4. Qi T, et al.
    Regulation of Jasmonate-Induced Leaf Senescence by Antagonism between bHLH Subgroup IIIe and IIId Factors in Arabidopsis.
    Plant Cell, 2015. 27(6): p. 1634-49
    [PMID:26071420]
  5. de Torres Zabala M, et al.
    Novel JAZ co-operativity and unexpected JA dynamics underpin Arabidopsis defence responses to Pseudomonas syringae infection.
    New Phytol., 2016. 209(3): p. 1120-34
    [PMID:26428397]
  6. Yu J, et al.
    JAZ7 negatively regulates dark-induced leaf senescence in Arabidopsis.
    J. Exp. Bot., 2016. 67(3): p. 751-62
    [PMID:26547795]
  7. Chen X,Huang H,Qi T,Liu B,Song S
    New perspective of the bHLH-MYB complex in jasmonate-regulated plant fertility in arabidopsis.
    Plant Signal Behav, 2016. 11(2): p. e1135280
    [PMID:26829586]
  8. Schmiesing A,Emonet A,Gouhier-Darimont C,Reymond P
    Arabidopsis MYC Transcription Factors Are the Target of Hormonal Salicylic Acid/Jasmonic Acid Cross Talk in Response to Pieris brassicae Egg Extract.
    Plant Physiol., 2016. 170(4): p. 2432-43
    [PMID:26884488]
  9. Thatcher LF, et al.
    Characterization of a JAZ7 activation-tagged Arabidopsis mutant with increased susceptibility to the fungal pathogen Fusarium oxysporum.
    J. Exp. Bot., 2016. 67(8): p. 2367-86
    [PMID:26896849]
  10. Gao C, et al.
    MYC2, MYC3, and MYC4 function redundantly in seed storage protein accumulation in Arabidopsis.
    Plant Physiol. Biochem., 2016. 108: p. 63-70
    [PMID:27415132]
  11. Gimenez-Ibanez S, et al.
    JAZ2 controls stomata dynamics during bacterial invasion.
    New Phytol., 2017. 213(3): p. 1378-1392
    [PMID:28005270]
  12. Lian TF,Xu YP,Li LF,Su XD
    Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA.
    Cell Rep, 2017. 19(7): p. 1334-1342
    [PMID:28514654]
  13. Wang H, et al.
    The bHLH Transcription Factors MYC2, MYC3, and MYC4 Are Required for Jasmonate-Mediated Inhibition of Flowering in Arabidopsis.
    Mol Plant, 2017. 10(11): p. 1461-1464
    [PMID:28827172]
  14. Song S, et al.
    MYC5 is Involved in Jasmonate-Regulated Plant Growth, Leaf Senescence and Defense Responses.
    Plant Cell Physiol., 2017. 58(10): p. 1752-1763
    [PMID:29017003]
  15. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  16. Han X, et al.
    Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons.
    Plant Physiol., 2018. 176(4): p. 2871-2885
    [PMID:29496884]