PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID RrC1462_p1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Raphanus
Family TCP
Protein Properties Length: 318aa    MW: 33878 Da    PI: 7.9753
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
RrC1462_p1genomeMSUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP130.31.9e-40511712115
         TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssasec.eaesssssasnsssg........... 88 
                 ++k+++++++hTkv+gR+RR+R++a caar+F+L++eLG+++d++tieWLlqqa pa++++tgt++++a+++  + s +ss s+ s++           
  RrC1462_p1  51 PPKRTSTKDRHTKVEGRGRRIRMPAMCAARVFQLTRELGHKSDGETIEWLLQQAGPAVIAATGTGTIPANFTsLNISLRSSRSSLSAAhlrttpssyyf 149
                 789******************************************************************999855555555553333345566644444 PP

         TCP  89 .....kaaksaakskksqksaasalnlakesr 115
                      +          +++++ ++  +++es+
  RrC1462_p1 150 htpamA----------QHHQQLHQVRPKNESH 171
                 433220..........2222222222222222 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036349.6E-4055175IPR005333Transcription factor, TCP
PROSITE profilePS5136927.18757111IPR017887Transcription factor TCP subgroup
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0007623Biological Processcircadian rhythm
GO:0008283Biological Processcell proliferation
GO:0009735Biological Processresponse to cytokinin
GO:0010229Biological Processinflorescence development
GO:0010252Biological Processauxin homeostasis
GO:0031540Biological Processregulation of anthocyanin biosynthetic process
GO:0042023Biological ProcessDNA endoreduplication
GO:0048467Biological Processgynoecium development
Sequence ? help Back to Top
Protein Sequence    Length: 318 aa     Download sequence    Send to blast
MDPDPDHHQR PNFPLQLLDS SSSSSTSLAI IPSASSSDPN SDPNAPSKKP PPKRTSTKDR  60
HTKVEGRGRR IRMPAMCAAR VFQLTRELGH KSDGETIEWL LQQAGPAVIA ATGTGTIPAN  120
FTSLNISLRS SRSSLSAAHL RTTPSSYYFH TPAMAQHHQQ LHQVRPKNES HSCSSSQLVD  180
HNQMGNYLVQ STAGSLPTSQ TPATAPFWSS GENNTQNLWA FHHSGDVYNT SGGGGGGGGG  240
GAGGGGGVHL MNFPAPFALF SGQPLASGYG GGEHNHYGVL SALNAAYRPV QETENQQNRD  300
GDHHRNHQED GSASHHHP
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved the regulation of plant development. Together with TCP14, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in developing leaf blade and specific floral tissues (PubMed:21668538). Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1 (PubMed:25655823). Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers (PubMed:22267487). Involved in gynoecium and silique development. Modulates the development of the different tissues of the gynoecium through its participation in auxin and cytokinin responses. Modulates the expression of the cytokinin-responsive genes ARR7 and ARR15. May repress the expression of the auxin biosynthetic genes YUC1 and YUC4 (PubMed:26303297). Acts as negative regulator of anthocyanin accumulation under high light conditions. Modulates the expression of transcription factors involved in the induction of anthocyanin biosynthesis genes (PubMed:26574599). Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3 (PubMed:25757472). Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity (PubMed:24689742). {ECO:0000269|PubMed:21668538, ECO:0000269|PubMed:22267487, ECO:0000269|PubMed:24689742, ECO:0000269|PubMed:25655823, ECO:0000269|PubMed:25757472, ECO:0000269|PubMed:26303297, ECO:0000269|PubMed:26574599}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00224DAPTransfer from AT1G69690Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation with the lowest expression in the middle of the dark period (PubMed:21183706). Induced during seed imbibition (PubMed:25655823). Induced by cytokinin (PubMed:26303297). {ECO:0000269|PubMed:21183706, ECO:0000269|PubMed:25655823, ECO:0000269|PubMed:26303297}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3533300.0AK353330.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-24-O23.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018452668.10.0PREDICTED: transcription factor TCP15-like
SwissprotQ9C9L21e-141TCP15_ARATH; Transcription factor TCP15
TrEMBLA0A0D3CZD00.0A0A0D3CZD0_BRAOL; Uncharacterized protein
TrEMBLA0A3P6HDF30.0A0A3P6HDF3_BRAOL; Uncharacterized protein
STRINGBo6g110290.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM129651830
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G69690.11e-121TCP family protein
Publications ? help Back to Top
  1. Steiner E, et al.
    The Putative O-Linked N-Acetylglucosamine Transferase SPINDLY Inhibits Class I TCP Proteolysis to Promote Sensitivity to Cytokinin.
    Plant Physiol., 2016. 171(2): p. 1485-94
    [PMID:27208284]
  2. Dong H, et al.
    Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis.
    Genes Dev., 2017. 31(2): p. 197-208
    [PMID:28167503]
  3. Zhang N, et al.
    MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis.
    Plant J., 2018. 93(1): p. 66-78
    [PMID:29086441]
  4. Mazur MJ, et al.
    Arabidopsis TCP Transcription Factors Interact with the SUMO Conjugating Machinery in Nuclear Foci.
    Front Plant Sci, 2017. 8: p. 2043
    [PMID:29250092]