PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 30093.m000368
Common NameLOC8277545, RCOM_1375410
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae; Ricinus
Family C2H2
Protein Properties Length: 372aa    MW: 42826.8 Da    PI: 6.5825
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
30093.m000368genomeJCVIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.30.0005279101323
                    ET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                    C+   Cgk+F +   L++H   H
  30093.m000368  79 CSydGCGKTFIDAGALRKHSHIH 101
                    78889**************7766 PP

2zf-C2H213.70.00019106130123
                    EEET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                    y+C+   C k F ++s LkrH   H
  30093.m000368 106 YVCHyeGCQKKFLDSSKLKRHFLIH 130
                    9********************8877 PP

3zf-C2H221.75.3e-07136160123
                    EEET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                    ++Cp   Cgk Fs   nL++H++tH
  30093.m000368 136 FVCPheGCGKAFSLDFNLRSHMKTH 160
                    89**********************9 PP

4zf-C2H213.40.00023166190123
                    EEET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                    + Cp   Cgk++ + + Lk+H + H
  30093.m000368 166 HICPypECGKRYAHEYKLKNHVSAH 190
                    679999***************9995 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.3E-1372102IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.92877106IPR007087Zinc finger, C2H2
SMARTSM003550.002877101IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576677.94E-880130No hitNo description
Gene3DG3DSA:3.30.160.601.4E-13103125IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.008106130IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.965106135IPR007087Zinc finger, C2H2
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576674.04E-14117169No hitNo description
Gene3DG3DSA:3.30.160.603.5E-20126160IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003553.1E-4136160IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.695136165IPR007087Zinc finger, C2H2
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.6E-8161192IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.1166190IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.64166195IPR007087Zinc finger, C2H2
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.2E-8224252IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.054229254IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.432229259IPR007087Zinc finger, C2H2
PROSITE patternPS000280231254IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 372 aa     Download sequence    Send to blast
METQFAHNLF ERRPIIKSKT PAVKWFKEWV PQDVVATGGK CYVLKWVTET QLKALKEKAK  60
EPPAPEPEPE PTTEVLFLCS YDGCGKTFID AGALRKHSHI HGEKQYVCHY EGCQKKFLDS  120
SKLKRHFLIH TGERDFVCPH EGCGKAFSLD FNLRSHMKTH SQENYHICPY PECGKRYAHE  180
YKLKNHVSAH HEKHSTVETV KYATPPEKVT KVSKPSAGVY ATPTLDRPYA CPYEGCIKAY  240
IHEYKLKLHL RKEHPGHMSD ENAENASPNA DNEMDEGSDQ DAYAEKHVNG KTQKQSRPKP  300
NLKMPPAKLT QRKGSSPHRA TLNVVKKPWP VKEETYEEED SEETEEEDRD NAEDGWRYGE  360
NEDDDEETEY ED
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C2e-32791908119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap30093.m000368
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002529014.10.0zinc finger transcription factor YY1
SwissprotQ2V3L31e-157YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLB9SSP50.0B9SSP5_RICCO; Nucleic acid binding protein, putative
STRINGXP_002529014.10.0(Ricinus communis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-148C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]