PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 30093.m000367
Common NameRCOM_1375300
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae; Ricinus
Family C2H2
Protein Properties Length: 326aa    MW: 37362.5 Da    PI: 6.1264
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
30093.m000367genomeJCVIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.50.0002179101323
                    ET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                    C+   Cgk+F +   L++H   H
  30093.m000367  79 CSneGCGKTFIDAGALRKHAHIH 101
                    77779**************9877 PP

2zf-C2H211.90.00071106130123
                    EEET..TTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                    y C+   C+k F + s L+rH  +H
  30093.m000367 106 YACHyeGCTKKFLDGSKLRRHYLSH 130
                    89*******************9998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.1E-1272102IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.90777106IPR007087Zinc finger, C2H2
SMARTSM003550.01377101IPR015880Zinc finger, C2H2-like
SuperFamilySSF576675.35E-678102No hitNo description
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576673.16E-8101143No hitNo description
Gene3DG3DSA:3.30.160.602.0E-11103125IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.039106130IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.695106135IPR007087Zinc finger, C2H2
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.6E-8126145IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
Gene3DG3DSA:3.30.160.609.4E-8175204IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.054181206IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.473181211IPR007087Zinc finger, C2H2
PROSITE patternPS000280183206IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 326 aa     Download sequence    Send to blast
METQFIQNLF ERRSIIKSNA PAVKWFREWV PQDVAATGGR CLVLKWVTEN QLKALKEKNE  60
EPPEPEPEPE PTTEVLFLCS NEGCGKTFID AGALRKHAHI HGEKQYACHY EGCTKKFLDG  120
SKLRRHYLSH TGERDFICPH EGCGKHATVE PVKYATPLEK TAKIRKPSAG VYATPSPDHP  180
YACPYEGCIK AYIHEYKLKL HLRKEHPGHT SDEDAVHASL NADNYMNEAS DQDVYAEKRV  240
NRKSKKQNRA KPNLKMPPAK LTRRKGSSLS RATTNVVKKP WPVKEETYEE EDSEETEDED  300
RDDNAEDGWR YGENNEDDDE DTEHEE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C2e-19792028114PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap30093.m000367
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015580751.10.0zinc finger transcription factor YY1
SwissprotQ2V3L31e-102YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLB9SSP40.0B9SSP4_RICCO; Uncharacterized protein
STRINGXP_002529013.10.0(Ricinus communis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.17e-98C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]