PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Phvul.007G269500.1
Common NamePHAVU_007G269500g
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Phaseolus
Family E2F/DP
Protein Properties Length: 468aa    MW: 51485.7 Da    PI: 4.954
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Phvul.007G269500.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.86.5e-27147212171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                         r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Phvul.007G269500.1 147 RYDSSLGLLTKKFINLVKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 212
                         6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.105.7E-29144214IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467856.67E-17147210IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.2E-34147212IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.7E-24149212IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440745.23E-32225329No hitNo description
CDDcd146601.45E-47225329No hitNo description
PfamPF164212.1E-33228327IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 468 aa     Download sequence    Send to blast
MSTAAGPPDR RASPPRGPAG TPVRPPLKRH LAFVTKPPFA PPDDYHSFSS IDSRRLADEA  60
VVVRSPYIKR KGGMNDSEGE SHAQKWSNSP GYTNISNITS SPFKTPVSAK GGRTQKAKAS  120
KEGRSCPPTP ISNAGSPSPL TPASSCRYDS SLGLLTKKFI NLVKHAEDGI LDLNKAAETL  180
EVQKRRIYDI TNVLEGIGLI EKKLKNRIHW KGIESSTPGE VDGDISVLKE EVEKLSLEEQ  240
GLDDQIREMQ ERLRRLSEKE SNQKCLFVTE DDIKSLPCFQ NETLIAIKAP HGTTLEVPDP  300
EEAVDYPQRR YRIILRSTMG PIDVYLISQF EEKFEEVNGA ELPMIPVASS SESNEQLMTE  360
MVPAESSGKE FEPQTQLSSH AYSDLNASQE FAGGMMKIVP SDVDNDADYW LLSDADVSIT  420
DMWRTDSTVD WNGVDMLHPD FGIISRPQTP SSGFVEVPTP GANSNQK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A5e-25142213274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPhvul.007G269500.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0930461e-108BT093046.1 Soybean clone JCVI-FLGm-15I8 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007145806.10.0hypothetical protein PHAVU_007G269500g
SwissprotQ9FNY01e-161E2FA_ARATH; Transcription factor E2FA
TrEMBLV7BL690.0V7BL69_PHAVU; Uncharacterized protein
STRINGXP_007145806.10.0(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-156E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]