PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Potri.004G221700.4
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus
Family C2H2
Protein Properties Length: 263aa    MW: 30157.1 Da    PI: 6.0238
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Potri.004G221700.4genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H221.37e-072549123
                        EEET..TTTEEESSHHHHHHHHHHT CS
             zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                        + Cp   Cgk Fs   nL++H++tH
  Potri.004G221700.4 25 FICPheGCGKAFSLDFNLRSHMKTH 49
                        78**********************9 PP

2zf-C2H214.69.4e-055579123
                        EEET..TTTEEESSHHHHHHHHHHT CS
             zf-C2H2  1 ykCp..dCgksFsrksnLkrHirtH 23
                        + Cp   Cgk++ + + Lk+Hi +H
  Potri.004G221700.4 55 HICPypECGKRYAHEYKLKNHIGSH 79
                        679999****************885 PP

3zf-C2H213.70.00019118143123
                         EEET..TTTEEESSHHHHHHHHHH.T CS
             zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                         y Cp   C k + + + Lk H+r+ H
  Potri.004G221700.4 118 YICPyeGCEKDYIHEYKLKLHLRReH 143
                         89**********************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576671.03E-14659No hitNo description
Gene3DG3DSA:3.30.160.605.4E-20951IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003553.9E-42549IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.5912554IPR007087Zinc finger, C2H2
PROSITE patternPS0002802749IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.608.7E-85279IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.8245584IPR007087Zinc finger, C2H2
SMARTSM003550.0675579IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002805780IPR007087Zinc finger, C2H2
SuperFamilySSF576672.91E-5113141No hitNo description
Gene3DG3DSA:3.30.160.603.3E-9116141IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.016118143IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.349118148IPR007087Zinc finger, C2H2
PROSITE patternPS000280120143IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 263 aa     Download sequence    Send to blast
MRKGKFLDSS KLKRHFLIHT GERDFICPHE GCGKAFSLDF NLRSHMKTHS QENYHICPYP  60
ECGKRYAHEY KLKNHIGSHH EKNPTPEVVK YATPPERIPK NAKTPPGVYG SASSDRPYIC  120
PYEGCEKDYI HEYKLKLHLR REHPGHMADE NAENATPNAD NELDEASDQD AYGGKRVNGK  180
SQKQSRSKPN LKMPPVKIRQ RKGSSPSPAT LNVVKKPWTI KDETYEEEED SEETEEEDRD  240
NAEDGWRYGG NEDDDEETED ED*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C1e-2261394117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Pth.110750.0bud| stem
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Rapidly induced following seed germination, especially in tender cotyledons. {ECO:0000269|PubMed:26961720}.
UniprotTISSUE SPECIFICITY: Mostly expressed in flowers, to a lower extent in seedlings, stems and leaves, and, at low levels, in roots and senescent leaves. {ECO:0000269|PubMed:26961720}.
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapPotri.004G221700.4
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEF1485070.0EF148507.1 Populus trichocarpa x Populus deltoides clone WS0131_N16 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006385011.11e-170zinc finger transcription factor YY1
SwissprotQ2V3L31e-100YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A2K2AYI31e-169A0A2K2AYI3_POPTR; Uncharacterized protein
STRINGPOPTR_0004s23050.11e-169(Populus trichocarpa)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.23e-98C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]