PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Prupe.3G032300.3.p
Common NameERF2.a, PRUPE_ppa006366mg
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Amygdaleae; Prunus
Family ERF
Protein Properties Length: 383aa    MW: 42495.9 Da    PI: 4.5636
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Prupe.3G032300.3.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP259.48.3e-19112161255
                 AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                         +y+G+r+++ +g+W+AeIrdp++     r++lg+f taeeAa+a++  +++++g
  Prupe.3G032300.3.p 112 QYRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTFNTAEEAARAYDSEARRIRG 161
                         69*******.**********954...4************************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003808.0E-38112175IPR001471AP2/ERF domain
SuperFamilySSF541715.36E-22112171IPR016177DNA-binding domain
PROSITE profilePS5103223.947112169IPR001471AP2/ERF domain
CDDcd000181.39E-32112170No hitNo description
Gene3DG3DSA:3.30.730.101.9E-32112171IPR001471AP2/ERF domain
PRINTSPR003671.1E-11113124IPR001471AP2/ERF domain
PfamPF008471.5E-11113161IPR001471AP2/ERF domain
PRINTSPR003671.1E-11135151IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0070483Biological Processdetection of hypoxia
GO:0005634Cellular Componentnucleus
GO:0005886Cellular Componentplasma membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 383 aa     Download sequence    Send to blast
MCGGAIISDF IAPTRSRLTA DYLWPDLKKP SSDKRFSKPL RPEIIDLDHD FEADFQEFKD  60
ESDVDEDDEM VEAKPSAFSA GKPSSARGST TVKLVEFNGQ AEKSAKRKRK NQYRGIRQRP  120
WGKWAAEIRD PRKGVRVWLG TFNTAEEAAR AYDSEARRIR GKKAKVNFPD ETPRSSAKRS  180
VKANPQKMLP KTNTNAVQPN LNQNINFVND PNQDYYNAMG FLDEKPATNN FGFMSTFPAN  240
EDVALKSSTP SDAVPLYFSS DQGSNSFDCS DFGWGEQGSK TPEISSVLSC VMEESDDSLF  300
LEDASPTKKL KSNPEDLVPV QDNAGKTLTD ELSAFEMKYF QTPYLDGSWD ASVDAFLSTD  360
ATQDGGNSVD FWSFDDLIGG GF*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A3e-21112169260ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
5wx9_A6e-211111711374Ethylene-responsive transcription factor ERF096
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ppe.2240.0fruit| leaf
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Highly expressed in seedlings, leaves, flowers, siliques and germinating seeds. {ECO:0000269|PubMed:22020282}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269|PubMed:22020282, ECO:0000269|PubMed:22530619}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00204DAPTransfer from AT1G53910Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapPrupe.3G032300.3.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269|PubMed:22020282}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHQ8250960.0HQ825096.1 Prunus persica cultivar Venture ethylene responsive factor (ERF2.a) mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007215452.10.0ethylene-responsive transcription factor RAP2-12
SwissprotQ9SSA82e-83RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBLH2BDK50.0H2BDK5_PRUPE; Ethylene responsive factor (Fragment)
STRINGEMJ166520.0(Prunus persica)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G53910.32e-83related to AP2 12
Publications ? help Back to Top
  1. Sherif S,El-Sharkawy I,Paliyath G,Jayasankar S
    Differential expression of peach ERF transcriptional activators in response to signaling molecules and inoculation with Xanthomonas campestris pv. pruni.
    J. Plant Physiol., 2012. 169(7): p. 731-9
    [PMID:22410465]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Kosmacz M, et al.
    The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration.
    Plant Cell Environ., 2015. 38(6): p. 1094-103
    [PMID:25438831]
  4. Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F
    Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana.
    Plant Sci., 2015. 236: p. 37-43
    [PMID:26025519]
  5. Gasch P, et al.
    Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    Plant Cell, 2016. 28(1): p. 160-80
    [PMID:26668304]
  6. Gonzali S, et al.
    Universal stress protein HRU1 mediates ROS homeostasis under anoxia.
    Nat Plants, 2015. 1: p. 15151
    [PMID:27251529]
  7. Paul MV, et al.
    Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia.
    Plant Physiol., 2016. 172(1): p. 141-53
    [PMID:27372243]
  8. Shahzad Z, et al.
    A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics.
    Cell, 2016. 167(1): p. 87-98.e14
    [PMID:27641502]
  9. Yao Y, et al.
    ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis.
    New Phytol., 2017. 213(4): p. 1667-1681
    [PMID:28164334]
  10. Giuntoli B,Licausi F,van Veen H,Perata P
    Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants.
    Front Plant Sci, 2017. 8: p. 591
    [PMID:28487707]
  11. Yao Y,Chen X,Wu AM
    ERF-VII members exhibit synergistic and separate roles in Arabidopsis.
    Plant Signal Behav, 2017. 12(6): p. e1329073
    [PMID:28537474]
  12. Eysholdt-Derzsó E,Sauter M
    Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling.
    Plant Physiol., 2017. 175(1): p. 412-423
    [PMID:28698356]
  13. Giuntoli B, et al.
    Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana.
    Plant Cell Environ., 2017. 40(10): p. 2333-2346
    [PMID:28741696]