PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pp3c26_11550V3.1.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrella
Family ARF
Protein Properties Length: 804aa    MW: 88782 Da    PI: 6.8275
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pp3c26_11550V3.1.pgenomeCOSMOSSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B372.45.8e-23133234199
                         EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE CS
                  B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkl 84 
                         f+k+lt sd++++g +++p++ ae+        ++++++  +l+ +d++ + W +++iyr++++r++lt+GW+ Fv+ ++L++gD+v+F  
  Pp3c26_11550V3.1.p 133 FCKTLTASDTSTHGGFSIPRRAAEKVfppldftKSPPAQ--ELVARDLHDQDWHFRHIYRGQPRRHLLTTGWSVFVSIKRLQAGDSVLFI- 220
                         99*****************************86666555..8************************************************. PP

                         -SSSEE..EEEEE-S CS
                  B3  85 dgrsefelvvkvfrk 99 
                          ++++ +l+++++r+
  Pp3c26_11550V3.1.p 221 -RDDKDHLLLGIRRA 234
                         .45677789999997 PP

2Auxin_resp1125.8e-37259342183
          Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                         a+haa+t+s F+++YnPr+s+seFv++++k++kal+ ++v++GmRf+mafete+s+ r+++Gt++ + dldp rWp+S WrsLk
  Pp3c26_11550V3.1.p 259 ASHAAATSSRFKIFYNPRQSPSEFVIPLAKYQKALYnTQVTLGMRFRMAFETEESNVRKYMGTITCIGDLDPARWPKSDWRSLK 342
                         789*******************************98799*******************************************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019364.45E-47122262IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.103.9E-40126248IPR015300DNA-binding pseudobarrel domain
CDDcd100171.37E-20132233No hitNo description
SMARTSM010194.2E-21133235IPR003340B3 DNA binding domain
PfamPF023624.3E-21133234IPR003340B3 DNA binding domain
PROSITE profilePS5086312.294133235IPR003340B3 DNA binding domain
PfamPF065071.1E-32259342IPR010525Auxin response factor
PROSITE profilePS5174521.818735803IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009734Biological Processauxin-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 804 aa     Download sequence    Send to blast
MYSNPPARLS ASGHVSSTMD PGGRRSLNSE LWHACAGSLV SLPPVGSRVV YFPQGHIEQV  60
AASTQKEADV PIPNYPSLPS RLFCLLDNVS LHADHETDEV YAQMTLLPIQ NSEKEALLAP  120
DSVIPNKQPS EYFCKTLTAS DTSTHGGFSI PRRAAEKVFP PLDFTKSPPA QELVARDLHD  180
QDWHFRHIYR GQPRRHLLTT GWSVFVSIKR LQAGDSVLFI RDDKDHLLLG IRRANRQQSV  240
MPSSVLSSDS MHFGVLAAAS HAAATSSRFK IFYNPRQSPS EFVIPLAKYQ KALYNTQVTL  300
GMRFRMAFET EESNVRKYMG TITCIGDLDP ARWPKSDWRS LKVGWDESIA GDRQLRVSLW  360
EIEPTPTPFL LCPPPVALRS KRPRGMQEEE DALEMLMKKS HMWPHGSDPS VSLKVGGLRL  420
DPLWMRLPQP RLGPMVSSPQ SGYYRALAAA ALQEIRSVDP PTQLLPQSAS SSQLFFGQPQ  480
SQSQPQQLMQ HINDIPGPLL QLTTSQTQTV DLANPVGPSS SYRESDMHMT SPTTMSNSLA  540
LQGMMRRAST SATLSFSEGN QITSLMRKSH NGLQPYGTVQ GVIQASTSWF SNQSDSQALI  600
SSQQSRVEAS SGGVPESYAL PQNNESSLHQ GLGHQLPFGF RSNDQDSDQL QADRSHLLFG  660
MSIDQPLGGS SVVSPQSYRK SKDDTGNNML LTAYGPPVTP DSMNNGILSG EGLDGNGLFQ  720
RNSGWPAMPV AIPPRTFTKV HKLGSVGRSL DVRNFSNYTE LRQELARRFQ LDCLMEDPSS  780
SGWQIVFVDN EDDTLLLGDD PWE*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1552036942393Auxin response factor 5
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in sepals at stages 11, 12 and 13 of flower development. Highly expressed in petals at stages 9-10, decreases at stage 11 and disappears after flower stage 12. In anthers, expressed at stage 11 in the tapetum, disappears early in stage 12 when the tapetum degrades and reappears throughout the anther late in stage 12 to persist at least until stage 13. In stamen filaments, expressed at stages 12 to 13, especially near the apical end of the filament. Expressed throughout the gynoecium at early stages up to stage 12, especially strongly in ovules. Expression in gynoecium decreases late in stage 12, but persists through stage 13, especially near the apical end including the style. {ECO:0000269|PubMed:16107481}.
UniprotTISSUE SPECIFICITY: Expressed in the whole plant. {ECO:0000269|PubMed:10476078}.
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF8. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024366632.10.0auxin response factor 6-like isoform X1
RefseqXP_024366633.10.0auxin response factor 6-like isoform X1
RefseqXP_024366635.10.0auxin response factor 6-like isoform X1
SwissprotQ9ZTX80.0ARFF_ARATH; Auxin response factor 6
TrEMBLA0A2K1ICQ20.0A0A2K1ICQ2_PHYPA; Auxin response factor
STRINGPP1S6_240V6.10.0(Physcomitrella patens)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP8561456
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G30330.11e-176auxin response factor 6
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Oh E, et al.
    Cell elongation is regulated through a central circuit of interacting transcription factors in the Arabidopsis hypocotyl.
    Elife, 2015.
    [PMID:24867218]
  3. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  4. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  5. Asahina M,Satoh S
    Molecular and physiological mechanisms regulating tissue reunion in incised plant tissues.
    J. Plant Res., 2015. 128(3): p. 381-8
    [PMID:25736731]
  6. Batista VG,Pinheiro MP,Melo Filho PA,Santos RC,Lima LM
    Temporal and tissue expression of genes involved in buds of earliness cotton cultivar.
    Genet. Mol. Res., 2015. 14(3): p. 7386-94
    [PMID:26214417]
  7. Li P, et al.
    Ca(2+) -regulated and diurnal rhythm-regulated Na(+) /Ca(2+) exchanger AtNCL affects flowering time and auxin signalling in Arabidopsis.
    Plant Cell Environ., 2016. 39(2): p. 377-92
    [PMID:26296956]
  8. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  9. Luo S, et al.
    Constitutive Expression of OsIAA9 Affects Starch Granules Accumulation and Root Gravitropic Response in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 1156
    [PMID:26734051]
  10. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  11. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  12. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]