PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Pp3c14_16990V3.15.p
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Bryophyta; Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrella
Family ARF
Protein Properties Length: 934aa    MW: 104372 Da    PI: 8.2262
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Pp3c14_16990V3.15.pgenomeCOSMOSSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B379.72.9e-25184285199
                          EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEE CS
                   B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFk 83 
                          f+k+lt sd++++g +++p++ ae+        ++++++  +l+ +d++ ++W +++iyr++++r++lt+GW+ Fv+a++L++gD v+F+
  Pp3c14_16990V3.15.p 184 FCKTLTASDTSTHGGFSIPRRAAEKVfppldyaQIPPAQ--ELKARDLHDQEWHFRHIYRGQPRRHLLTTGWSVFVSAKRLQAGDAVLFT 271
                          99*****************************97766665..8************************************************ PP

                          E-SSSEE..EEEEE-S CS
                   B3  84 ldgrsefelvvkvfrk 99 
                            ++++++l ++++r+
  Pp3c14_16990V3.15.p 272 --RDNKGQLQLGIRRQ 285
                          ..5689999****997 PP

2Auxin_resp115.25.9e-38312393383
           Auxin_resp   3 haastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                           aa+t+s F+++YnPr+s+seFv++v+k++ka+   +vsvGmRf+m fete+ss rr++Gt++g+ dldp+rWpnS+WrsLk
  Pp3c14_16990V3.15.p 312 YAAATSSRFTIFYNPRQSPSEFVIPVAKYQKAIChLQVSVGMRFRMVFETEESSVRRYMGTITGMGDLDPIRWPNSHWRSLK 393
                          6899****************************9868********************************************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019364.84E-47173311IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.103.1E-42177299IPR015300DNA-binding pseudobarrel domain
CDDcd100171.41E-23183284No hitNo description
PfamPF023624.2E-23184285IPR003340B3 DNA binding domain
SMARTSM010191.6E-23184286IPR003340B3 DNA binding domain
PROSITE profilePS5086313.07184286IPR003340B3 DNA binding domain
PfamPF065071.2E-33312393IPR010525Auxin response factor
PROSITE profilePS5174525.301798891IPR000270PB1 domain
SuperFamilySSF542771.37E-6814877No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 934 aa     Download sequence    Send to blast
MDVSGEEDHS MCLTRSLSPG FLSDCSRFAK WRWKYGWRRW NVGYRLFMYL CNERLPSVGP  60
SVGSMAQPAE KVEKRSLNSE LWHACAGPLV LLPPVGSRVV YFPQGHTEQV AASMQKEVDA  120
HIPNYPNLPS RLVCLLDNVT LHADIETDEV YAQMTLIPVP PTNEKDAHMS PDIEMRSRQP  180
TEYFCKTLTA SDTSTHGGFS IPRRAAEKVF PPLDYAQIPP AQELKARDLH DQEWHFRHIY  240
RGQPRRHLLT TGWSVFVSAK RLQAGDAVLF TRDNKGQLQL GIRRQNRQQR VMPSSVLSSD  300
SMHIGVLAAA NYAAATSSRF TIFYNPRQSP SEFVIPVAKY QKAICHLQVS VGMRFRMVFE  360
TEESSVRRYM GTITGMGDLD PIRWPNSHWR SLKVGWDEST AGERKKRVSL WDIEPLTFPY  420
VLCPQPLAFR AKRPRGGRDE ETDSMLKKSS FWSGENSTDA LGRLTFRTPS LDSWMRPKQP  480
GLPMQENEHY RALEAAALEE IRTTSTAKNP MSRVQSSIPS SQMQFQPPHV LRQSSQHGEL  540
HMPEASGPLL QLSSSRPQSP FEVGINMPQC SGYSEGKIHM ASSLSASESF PLHSMLGRTH  600
LGCDTVQVTH VIRPGKSAQQ NLSGAAIHGS SAVVRDPQVS PSWYPPNRDL NQYDVSVRMN  660
QLDTSPTSRN PGSFTFPQQG EGIGQSNLAA LPAPTSSFMY RESGQAQDLV QSDRRLLFGV  720
SIEQQPLGDS HSVTSRHPQT FVKNKDAQSR FPGNIMLQGS YCPSTTADIP TVGGVVLDKI  780
GVFQRCAPWS IMSPAPMRTF TKVHKLGSVG RSIDVQKFQN YSELRAELAR LFNLEGLLED  840
PQTSGWQLVF VDNENDILLV GDDLWEEFVS CVRSIKILSP NEILRMSREQ LEILNPVPMQ  900
LRPTCSNSED ARTQLSPANA STMSLEHGHS GAG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1587441448388Auxin response factor 5
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in sepals at stages 11, 12 and 13 of flower development. Highly expressed in petals at stages 9-10, decreases at stage 11 and disappears after flower stage 12. In anthers, expressed at stage 11 in the tapetum, disappears early in stage 12 when the tapetum degrades and reappears throughout the anther late in stage 12 to persist at least until stage 13. In stamen filaments, expressed at stages 12 to 13, especially near the apical end of the filament. Expressed throughout the gynoecium at early stages up to stage 12, especially strongly in ovules. Expression in gynoecium decreases late in stage 12, but persists through stage 13, especially near the apical end including the style. {ECO:0000269|PubMed:16107481}.
UniprotTISSUE SPECIFICITY: Expressed in the whole plant. {ECO:0000269|PubMed:10476078}.
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF8. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024395055.10.0auxin response factor 19-like isoform X3
SwissprotQ9ZTX80.0ARFF_ARATH; Auxin response factor 6
TrEMBLA0A2K1J4P60.0A0A2K1J4P6_PHYPA; Auxin response factor
STRINGPP1S48_147V6.10.0(Physcomitrella patens)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G30330.10.0auxin response factor 6
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Oh E, et al.
    Cell elongation is regulated through a central circuit of interacting transcription factors in the Arabidopsis hypocotyl.
    Elife, 2015.
    [PMID:24867218]
  3. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  4. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  5. Asahina M,Satoh S
    Molecular and physiological mechanisms regulating tissue reunion in incised plant tissues.
    J. Plant Res., 2015. 128(3): p. 381-8
    [PMID:25736731]
  6. Batista VG,Pinheiro MP,Melo Filho PA,Santos RC,Lima LM
    Temporal and tissue expression of genes involved in buds of earliness cotton cultivar.
    Genet. Mol. Res., 2015. 14(3): p. 7386-94
    [PMID:26214417]
  7. Li P, et al.
    Ca(2+) -regulated and diurnal rhythm-regulated Na(+) /Ca(2+) exchanger AtNCL affects flowering time and auxin signalling in Arabidopsis.
    Plant Cell Environ., 2016. 39(2): p. 377-92
    [PMID:26296956]
  8. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  9. Luo S, et al.
    Constitutive Expression of OsIAA9 Affects Starch Granules Accumulation and Root Gravitropic Response in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 1156
    [PMID:26734051]
  10. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  11. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  12. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]