PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_008240463.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Amygdaleae; Prunus
Family ERF
Protein Properties Length: 316aa    MW: 34751.2 Da    PI: 4.8281
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_008240463.1genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP257.72.8e-184392255
             AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                    ++ GVr+++ +grWvAeI+d +   ++ r +lg+f taeeAa+a+++a+  l+g
  XP_008240463.1 43 KFVGVRQRP-SGRWVAEIKDTT---QKIRMWLGTFETAEEAARAYDEAACLLRG 92
                    799******.7*********32...35**********************99987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008476.6E-134392IPR001471AP2/ERF domain
SuperFamilySSF541714.18E-1943100IPR016177DNA-binding domain
CDDcd000186.98E-324399No hitNo description
Gene3DG3DSA:3.30.730.108.7E-2843100IPR001471AP2/ERF domain
SMARTSM003801.6E-3543106IPR001471AP2/ERF domain
PROSITE profilePS5103219.58543100IPR001471AP2/ERF domain
PRINTSPR003671.2E-74455IPR001471AP2/ERF domain
PRINTSPR003671.2E-76682IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 316 aa     Download sequence    Send to blast
MEFQFQQQNQ ICFPAAAANK AVGIPISKVG KSKGRTRSNN TNKFVGVRQR PSGRWVAEIK  60
DTTQKIRMWL GTFETAEEAA RAYDEAACLL RGSNTRTNFI THVSLDSPLA SRIRNLLNTK  120
RGGSNKQVIE QTSSSIGDHD DMNASHPPTS STTSNDKYMT SNISTASTST CNSTSSGSDT  180
LSSEVFQDSQ LFDDVYRPDL RHCNEEFELS SSASQSNLSW GGFEPGVDEF SFAQQVFDLP  240
KHQAAAAASS STTSSTTTTT TAVEADSEFL EFERMKVERQ ISASLYAMNG VQEYMDTVYD  300
PNEPSWDLPP ICPLFC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A2e-1434109581Ethylene-responsive transcription factor ERF096
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs) (PubMed:17449807, PubMed:17827349). Binds to the GCC-box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs (PubMed:17827349). Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation and maintenance, and nodule development. Necessary for NF-induced gene expression and spontaneous nodulation activated by CCAMK. Functions downstream of CCAMK to activate nodulation gene expression (PubMed:17449807). Involved in early stages of root nodule development. Functions redundantly with ERN2. Is essential with ERN2 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12 (PubMed:23077241, PubMed:27208242). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241, ECO:0000269|PubMed:27208242}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_008240463.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in roots from 1 to 21 day after inoculation with Sinorhizobium meliloti (PubMed:17449807). Induced by Nod factors in root hairs (PubMed:17827349). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1705802e-69AC170580.3 Medicago truncatula chromosome 7 clone mte1-32m6, complete sequence.
GenBankBT0528332e-69BT052833.1 Medicago truncatula clone MTYFH_FI_FJ_FK1G-G-8 unknown mRNA.
GenBankBT1456242e-69BT145624.1 Medicago truncatula clone JCVI-FLMt-17M3 unknown mRNA.
GenBankDQ9849422e-69DQ984942.1 Medicago truncatula Ser/Thr protein kinase (PRK), exostosin-like protein (EXO), putative RNA binding protein (RAN BP), transcription factor ERF (ERN), and alpha-tubulin (aTUB) genes, complete cds; and unknown gene.
GenBankEF3963302e-69EF396330.1 Medicago truncatula ERF transcription factor (ERN) gene, complete cds.
GenBankEU0388022e-69EU038802.2 Medicago truncatula ERN1 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008240463.10.0PREDICTED: ethylene-responsive transcription factor RAP2-11-like
SwissprotA2Q5W11e-103ERN1_MEDTR; Ethylene-responsive transcription factor ERN1
TrEMBLM5VRY30.0M5VRY3_PRUPE; Uncharacterized protein
STRINGXP_008240463.10.0(Prunus mume)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33413069
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G19790.11e-29related to AP2 11
Publications ? help Back to Top
  1. Cerri MR, et al.
    Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
    Plant Physiol., 2012. 160(4): p. 2155-72
    [PMID:23077241]
  2. Tang H, et al.
    An improved genome release (version Mt4.0) for the model legume Medicago truncatula.
    BMC Genomics, 2014. 15: p. 312
    [PMID:24767513]
  3. Cerri MR, et al.
    The Symbiosis-Related ERN Transcription Factors Act in Concert to Coordinate Rhizobial Host Root Infection.
    Plant Physiol., 2016. 171(2): p. 1037-54
    [PMID:27208242]