PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID PSME_00009555-RA
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Acrogymnospermae; Pinidae; Pinales; Pinaceae; Pseudotsuga
Family C2H2
Protein Properties Length: 366aa    MW: 41326 Da    PI: 8.3534
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PSME_00009555-RAgenomePRSView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.60.00043118140323
                       ET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                       C+   Cgk+F++   L++H  +H
  PSME_00009555-RA 118 CSyeGCGKTFTDGGALRKHSHVH 140
                       77779**************8776 PP

2zf-C2H2130.00031145169123
                       EEET..TTTEEESSHHHHHHHHHHT CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                       ++C+   Cg+ F ++s LkrH   H
  PSME_00009555-RA 145 HVCHyeGCGRKFLDSSKLKRHFLIH 169
                       79*******************8877 PP

3zf-C2H213.80.00017219244123
                       EEET..TTTEEESSHHHHHHHHHH.T CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                       + Cp   C+k++ + + L+ H+r+ H
  PSME_00009555-RA 219 FACPyeGCDKCYIHEYKLNLHLRReH 244
                       78*********************999 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.602.5E-12115142IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0051116140IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.365116145IPR007087Zinc finger, C2H2
SuperFamilySSF576678.29E-7117141No hitNo description
PROSITE patternPS000280118140IPR007087Zinc finger, C2H2
SuperFamilySSF576673.63E-9140182No hitNo description
Gene3DG3DSA:3.30.160.602.5E-12143165IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.027145169IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.902145174IPR007087Zinc finger, C2H2
PROSITE patternPS000280147169IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.4E-9166185IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576675.01E-5215242No hitNo description
Gene3DG3DSA:3.30.160.601.3E-7216241IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.018219244IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.099219246IPR007087Zinc finger, C2H2
PROSITE patternPS000280221244IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 366 aa     Download sequence    Send to blast
MYGFRGEGEV RRRRQELMSS SLGIPFENSR AMEALEQQHL YPHPQNQEQE QARQNKPQST  60
KAGGVKWIKE WVPQETVLNN GKCYFLKWVT EDTLKTLKEK QQEKEPESES LPPSLFLCSY  120
EGCGKTFTDG GALRKHSHVH GEKQHVCHYE GCGRKFLDSS KLKRHFLIHT GEKHFTCPHE  180
GCGKNLANAV KLPPQTEREF LHPKVPTSVY GSVPSDRPFA CPYEGCDKCY IHEYKLNLHL  240
RREHAGYAFE ENGRHGSDSE DEMDQGSDQD ANVRNAGIMT GSGRGRLRVT SNTSSATNLH  300
RKFSNAAAVD LNTKTSSRAI VEKDVRNKYF RGIGWSVGDS SFRGDTRTFQ SSSKGCLDEE  360
GGNNPK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C3e-241112401114PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankEF6783190.0EF678319.1 Picea sitchensis clone WS02914_E07 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010246046.11e-95PREDICTED: uncharacterized zinc finger protein At4g06634
SwissprotQ2V3L38e-72YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A1U7Z1V62e-94A0A1U7Z1V6_NELNU; uncharacterized zinc finger protein At4g06634
STRINGXP_010246046.14e-95(Nelumbo nucifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.16e-71C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]