PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID LOC_Os04g51070.1
Common NameBHLH141, DTD, EAT1, LOC4336865, Os04g0599300, OsJ_16023, OSJNBa0083N12.3, OSJNba0093F12.24
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa
Family bHLH
Protein Properties Length: 465aa    MW: 51521.7 Da    PI: 5.0441
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
LOC_Os04g51070.1genomeMSUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH35.71.6e-11264310354
                       HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
               HLH   3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                       +a+ + Er RR+++N +f +Lr l P++     +K++ a+i+  A+eYI +L
  LOC_Os04g51070.1 264 KANFATERERREQLNVKFRTLRMLFPNP-----TKNDRASIVGDAIEYIDEL 310
                       68899***********************.....9***************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088813.598261310IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.1E-8264310IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474593.16E-12264328IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.5E-8267316IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.6E-10268323IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.71E-8270315No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009555Biological Processpollen development
GO:0048658Biological Processanther wall tapetum development
GO:0052543Biological Processcallose deposition in cell wall
GO:0005634Cellular Componentnucleus
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0009066anatomyanther
PO:0001004developmental stageanther development stage
PO:0007130developmental stagesporophyte reproductive stage
Sequence ? help Back to Top
Protein Sequence    Length: 465 aa     Download sequence    Send to blast
MIVGAGYFED SHDQSLMAGS LIHDSNQAPA SSENTSIDLQ KFKVHPYSTE ALSNTANLAE  60
AARAINHLQH QLEIDLEQEV PPVETANWDP AICTIPDHII NHQFSEDPQN ILVEQQIQQY  120
DSALYPNGVY TPAPDLLNLM QCTMAPAFPA TTSVFGDTTL NGTNYLDLNG ELTGVAAVPD  180
SGSGLMFASD SALQLGYHGT QSHLIKDICH SLPQNYGLFP SEDERDVIIG VGSGDLFQEI  240
DDRQFDSVLE CRRGKGEFGK GKGKANFATE RERREQLNVK FRTLRMLFPN PTKNDRASIV  300
GDAIEYIDEL NRTVKELKIL VEQKRHGNNR RKVLKLDQEA AADGESSSMR PVRDDQDNQL  360
HGAIRSSWVQ RRSKECHVDV RIVDDEVNIK LTEKKKANSL LHAAKVLDEF QLELIHVVGG  420
IIGDHHIFMF NTKVSEGSAV YACAVAKKLL QAVDVQHQAL DIFN*
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Os.499950.0panicle
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO379891320.0
Expression AtlasQ7X8R0-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in developing anthers from stage 8 to stage 10 (PubMed:23519457). Expressed in developing anthers from stage 7 to stage 11 with a peak at stages 8 and 9. Highly expressed in the tapetum (PubMed:23385589). {ECO:0000269|PubMed:23385589, ECO:0000269|PubMed:23519457}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the regulation of tapetum programmed cell death (PCD) and degradation during male reproductive development (PubMed:23519457, PubMed:23385589). Interacts with TDR and promote tapetal PCD by regulating the expression of RTS, and the two lipid-transfer proteins C4 and C6, which function in microspore development (PubMed:23519457). Acts downstream from and interacts with TDR in the regulation of tapetal PCD. Regulates directly the aspartic protease AP25 and AP37 during tapetal PCD (PubMed:23385589). May not target the cysteine protease CP1 (PubMed:23519457, PubMed:23385589). {ECO:0000269|PubMed:23385589, ECO:0000269|PubMed:23519457}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapLOC_Os04g51070.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Male sterility due to failure of tapetum programmed cell death (PCD) and degeneration required for pollen maturation (PubMed:23519457). Male sterility due to delayed tapetal PCD and aborted pollen development (PubMed:23385589). {ECO:0000269|PubMed:23385589, ECO:0000269|PubMed:23519457}.
Phenotype -- Mutation ? help Back to Top
Source ID
RiceGEOs04g51070
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1195090.0AK119509.1 Oryza sativa Japonica Group cDNA clone:001-134-F08, full insert sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015634641.10.0PREDICTED: transcription factor bHLH91
RefseqXP_015634640.10.0PREDICTED: transcription factor bHLH91
RefseqXP_015634639.10.0PREDICTED: transcription factor bHLH91
SwissprotQ7X8R00.0EAT1_ORYSJ; Transcription factor EAT1
TrEMBLA0A0E0PDK50.0A0A0E0PDK5_ORYRU; Uncharacterized protein
STRINGLOC_Os04g51070.10.0(Oryza sativa Japonica Group)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP26591431
MonocotsOGMP19043796
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G31210.13e-56bHLH family protein
Publications ? help Back to Top
  1. Li X, et al.
    Genome-wide analysis of basic/helix-loop-helix transcription factor family in rice and Arabidopsis.
    Plant Physiol., 2006. 141(4): p. 1167-84
    [PMID:16896230]
  2. Niu N, et al.
    EAT1 promotes tapetal cell death by regulating aspartic proteases during male reproductive development in rice.
    Nat Commun, 2013. 4: p. 1445
    [PMID:23385589]
  3. Ji C, et al.
    A novel rice bHLH transcription factor, DTD, acts coordinately with TDR in controlling tapetum function and pollen development.
    Mol Plant, 2013. 6(5): p. 1715-8
    [PMID:23519457]