PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KN538686.1_FGP084
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza
Family EIL
Protein Properties Length: 581aa    MW: 63950.9 Da    PI: 4.745
Description EIL family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KN538686.1_FGP084genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN34731.9e-144784091303
                        XXXXXXXXXXXXXXXXXXXXXXX..XXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
               EIN3   1 eelkkrmwkdqmllkrlkerkkqlledkeaa..tgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpvegasds 90 
                        eel++rmw+d+m+lkrlke ++++ +d       + +k ++s+eqarrkkmsraQDgiLkYMlk+mevc+aqGfvYgiipekgkpv+gasd+
  KN538686.1_FGP084  78 EELERRMWRDRMKLKRLKELQLSRGKDPAGGavGDPSKPRQSQEQARRKKMSRAQDGILKYMLKMMEVCRAQGFVYGIIPEKGKPVSGASDN 169
                        8*********************98855544477788999***************************************************** PP

                        XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH---S--HHHH CS
               EIN3  91 LraWWkekvefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWWPtGkelwwg 182
                        Lr+WWkekv+fdrngpaai+kyqa+n++++ es+l + ++ ++hsl+elqDTtlgSLLsalmqhcdppqrr+plekg++pPWWPtG+e+ww 
  KN538686.1_FGP084 170 LRGWWKEKVRFDRNGPAAIAKYQADNAVPGCESELAS-GTGSPHSLQELQDTTLGSLLSALMQHCDPPQRRYPLEKGIPPPWWPTGDEEWWR 260
                        ***********************************66.****************************************************** PP

                        HHT--TT--.-----GGG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXXXXX.....XXXX CS
               EIN3 183 elglskdqgtppykkphdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsahss.....slrk 269
                        +lg++kdqg+ppykkphdlkkawkvsvLtavikhmsp+ie+ir+l+rqsk+lqdkm+ake  ++l+v++qee+++ ++ +  +        +
  KN538686.1_FGP084 261 QLGIPKDQGPPPYKKPHDLKKAWKVSVLTAVIKHMSPDIEKIRRLVRQSKCLQDKMTAKEISTWLAVVKQEEELYLKLNPGARppaptGGIT 352
                        ********************************************************************************944345442233 PP

                        XXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX........................X CS
               EIN3 270 qspkvtlsceqkedvegkkeskikhvqavktta........................g 303
                        ++ ++++s++ ++dv++ ++ k  ++ ++k+                          +
  KN538686.1_FGP084 353 SAISFNASSS-EYDVDVVDDCKGDEAGNQKAVVvadptafnlgaamlndkflmpasmK 409
                        5556666655.99***777666676666666555555556665555555554444441 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048731.4E-13178332No hitNo description
Gene3DG3DSA:1.10.3180.104.0E-74207340IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamilySSF1167682.75E-61211335IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001666Biological Processresponse to hypoxia
GO:0009873Biological Processethylene-activated signaling pathway
GO:0042742Biological Processdefense response to bacterium
GO:0071281Biological Processcellular response to iron ion
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 581 aa     Download sequence    Send to blast
MGGGLVMDQG MMFPGVHNFV DLLQQNGGDK NLGFGALVPQ TSSGEQCVMG EGDLVDPPPE  60
SFPDAGEDDS DDDVEDIEEL ERRMWRDRMK LKRLKELQLS RGKDPAGGAV GDPSKPRQSQ  120
EQARRKKMSR AQDGILKYML KMMEVCRAQG FVYGIIPEKG KPVSGASDNL RGWWKEKVRF  180
DRNGPAAIAK YQADNAVPGC ESELASGTGS PHSLQELQDT TLGSLLSALM QHCDPPQRRY  240
PLEKGIPPPW WPTGDEEWWR QLGIPKDQGP PPYKKPHDLK KAWKVSVLTA VIKHMSPDIE  300
KIRRLVRQSK CLQDKMTAKE ISTWLAVVKQ EEELYLKLNP GARPPAPTGG ITSAISFNAS  360
SSEYDVDVVD DCKGDEAGNQ KAVVVADPTA FNLGAAMLND KFLMPASMKE EATDQSTENK  420
PSPPAIFPAT YNTPNQALNN LDFGLPMDGQ RSITELMNMY DNNFVANKNL SNDNATIMER  480
PNAVNPRIQI EEGFFGQGSG IGGSNGGVFE DVNGMMQQPQ QTTPAQQQFF IRDDTPFGNQ  540
MGDINGASEF RFGSGFNMSG AVEYPGAMQG QQKNDGSNWY Y
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4zds_A2e-732093401132Protein ETHYLENE INSENSITIVE 3
4zds_B2e-732093401132Protein ETHYLENE INSENSITIVE 3
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor acting as a positive regulator in the ethylene response pathway (PubMed:16786297, PubMed:28829777, PubMed:27701783, PubMed:25995326). Required for the inhibition of root growth by ethylene in etiolated seedlings (PubMed:25995326, PubMed:28829777). Functions upstream of the auxin biosynthetic gene YUCCA8 and directly activates its expression (PubMed:28829777). Functions downstream of the ethylene signaling factor EIN2 in disease resistance against the rice blast fungus (Magnaporthe oryzae) (PubMed:27701783). Binds directly to the promoters of the NADPH oxidases RBOHA and RBOHB, and the jasmonate biosynthetic gene OPR4 to activate their expression during fungal infection (PubMed:27701783). May enhance disease resistance by facilitating reactive oxygen species (ROS) generation and jasmonate biosynthesis with subsequent phytoalexin accumulation during Magnaporthe oryzae infection (PubMed:27701783). Acts as negative regulator of salt tolerance (PubMed:25995326). During salt stress, activates the cation transporter HKT1, which mediates increased sodium uptake in roots, and contributes to sodium accumulation and salt toxicity (PubMed:25995326). Binds directly to the DNA sequence 5'-TGTTACAAATACC-3' in the promoter of the GA20OX2 gene to activate its expression at the transcriptional level during ethylene signaling (PubMed:30002253). Possesses transactivation activity in protoplasts (PubMed:25995326). {ECO:0000269|PubMed:16786297, ECO:0000269|PubMed:25995326, ECO:0000269|PubMed:27701783, ECO:0000269|PubMed:28829777, ECO:0000269|PubMed:30002253}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00367DAPTransfer from AT3G20770Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapKN538686.1_FGP084
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the fungal pathogen Magnaporthe oryzae. {ECO:0000269|PubMed:27701783}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMap-Retrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankCP0126110.0CP012611.1 Oryza sativa Indica Group cultivar RP Bio-226 chromosome 3 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015629858.10.0ETHYLENE INSENSITIVE 3-like 1 protein
SwissprotQ10M410.0EIL1A_ORYSJ; Protein ETHYLENE-INSENSITIVE 3-like 1a
TrEMBLA0A0E0NUE60.0A0A0E0NUE6_ORYRU; Uncharacterized protein
STRINGORUFI03G16290.10.0(Oryza rufipogon)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP63838168
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27050.11e-142ETHYLENE-INSENSITIVE3-like 1
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Yang C, et al.
    MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
    Plant Physiol., 2015. 169(1): p. 148-65
    [PMID:25995326]
  3. Yang C, et al.
    Activation of ethylene signaling pathways enhances disease resistance by regulating ROS and phytoalexin production in rice.
    Plant J., 2017. 89(2): p. 338-353
    [PMID:27701783]
  4. Qin H, et al.
    The activation of OsEIL1 on YUC8 transcription and auxin biosynthesis is required for ethylene-inhibited root elongation in rice early seedling development.
    PLoS Genet., 2017. 13(8): p. e1006955
    [PMID:28829777]
  5. Kuroha T, et al.
    Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding.
    Science, 2018. 361(6398): p. 181-186
    [PMID:30002253]