PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009589888.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 373aa    MW: 42503.1 Da    PI: 6.6246
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009589888.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.30.0005379101323
                     ET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                     C+   Cgk+F +   L++H   H
  XP_009589888.1  79 CSydGCGKTFIDAGALRKHSHIH 101
                     78889**************7766 PP

2zf-C2H216.52.4e-05106130123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     y+C+   Cgk F ++s LkrH   H
  XP_009589888.1 106 YVCHyeGCGKKFLDSSKLKRHFLIH 130
                     9********************8877 PP

3zf-C2H222.43.3e-07136160123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     y+Cp   Cgk Fs   nL++H++tH
  XP_009589888.1 136 YVCPheGCGKAFSLDFNLRSHMKTH 160
                     99**********************9 PP

4zf-C2H216.32.8e-05166191123
                     EEET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                     + Cp   Cgk++ + + Lk+Hi + H
  XP_009589888.1 166 HICPypECGKRYAHEYKLKNHIASsH 191
                     679999****************9988 PP

5zf-C2H216.13.1e-05229254123
                     EEET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                     y+Cp   C+ks+ + + L+ H+r+ H
  XP_009589888.1 229 YSCPyeGCDKSYIHEYKLNLHLRNmH 254
                     99*********************988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.3E-1372103IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.002877101IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.78377106IPR007087Zinc finger, C2H2
PROSITE patternPS00028079101IPR007087Zinc finger, C2H2
SuperFamilySSF576672.46E-880130No hitNo description
Gene3DG3DSA:3.30.160.602.3E-14104126IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.921106135IPR007087Zinc finger, C2H2
SMARTSM003550.0024106130IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280108130IPR007087Zinc finger, C2H2
SuperFamilySSF576673.99E-14117169No hitNo description
Gene3DG3DSA:3.30.160.602.0E-20127161IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.882136165IPR007087Zinc finger, C2H2
SMARTSM003551.7E-4136160IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280138160IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.5E-7162189IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.024166191IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.349166196IPR007087Zinc finger, C2H2
PROSITE patternPS000280168191IPR007087Zinc finger, C2H2
SuperFamilySSF576671.6E-5223251No hitNo description
Gene3DG3DSA:3.30.160.609.2E-9223251IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.344229259IPR007087Zinc finger, C2H2
SMARTSM003558.2E-4229254IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280231254IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 373 aa     Download sequence    Send to blast
METHMAHHLF ERRPIYKSKA PAAKWFKEWV PQDVVATGGK CYLLKWVNEA TLKALKEKPK  60
EPEVPVPEPE PTTEVLFLCS YDGCGKTFID AGALRKHSHI HGERQYVCHY EGCGKKFLDS  120
SKLKRHFLIH TGERDYVCPH EGCGKAFSLD FNLRSHMKTH SQENYHICPY PECGKRYAHE  180
YKLKNHIASS HQKNSTPDAP KYTPPVEKPM KTPKSSSAAY ASSSSDRPYS CPYEGCDKSY  240
IHEYKLNLHL RNMHPGHFPE DNAKNAQSNA DNEMDEGSDQ DAYAAKRGNG KIQKQSRPKP  300
SLKQPALKVA RKSSSASPAN ISIAAKKPWS VKEENYHEED SEETEEERDD VGDGWRYGEN  360
DDDDDDEETE EDE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C1e-33791898119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0176940.0AB017694.1 Nicotiana tabacum WREBP-2 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009589888.10.0PREDICTED: uncharacterized zinc finger protein At4g06634
SwissprotQ2V3L31e-157YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A1S3Y2F20.0A0A1S3Y2F2_TOBAC; uncharacterized zinc finger protein At4g06634-like
STRINGXP_009589888.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA73432332
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-136C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]