PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016503267.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 440aa    MW: 49580.8 Da    PI: 7.3093
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016503267.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H221.37.1e-07193214223
                     EETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   2 kCpdCgksFsrksnLkrHirtH 23 
                      C++Cgk F+r  nL+ H+r H
  XP_016503267.1 193 FCTICGKGFKRDANLRMHMRGH 214
                     6*******************98 PP

2zf-C2H214.10.00013312327621
                     TTEEESSHHHHHHHHH CS
         zf-C2H2   6 CgksFsrksnLkrHir 21 
                     Cg++Fsrk+ L rHi+
  XP_016503267.1 312 CGTTFSRKDKLFRHIS 327
                     **************97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576672.05E-5191216No hitNo description
SMARTSM003550.0026192214IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015712.03192219IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.2E-6193244IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280194214IPR007087Zinc finger, C2H2
SMARTSM00355180242275IPR015880Zinc finger, C2H2-like
SMARTSM0035533280302IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 440 aa     Download sequence    Send to blast
MEQQVNQRSE NHDFTRIQDW DPKAILKNMS FLEQKIHQLQ ELVRIIFDHR SLVGIQGNDL  60
SSQQQQLITA DLTSIIVQLI STAGSLLPTV KHHTFSSASP TTKQPAQFGG VSVPSEKGIN  120
AGALPHSVNV TKAEDQSNHV DLMGDCGIEQ KYAADEHEAN DEDEFHEEEN LPPGSYEILQ  180
LEKEEILAPH THFCTICGKG FKRDANLRMH MRGHGDEYKT PAALAQPHKD PSSRTMTLIK  240
RYSCPCVGCK RNKEHKRFQP LKTISCVKKH YRRTHCEKSY ACSRCNLKKF SVIADLRTHE  300
KHCGKDKWLC SCGTTFSRKD KLFRHISLFQ GHTPAIPLEE TKGFAETSDQ GHTGKATTEA  360
GGIGCELNVQ NGSGLQNTIN VKEDADNPGS YLSPLNIETS KLSELQEFPR PPFEDPENSF  420
SFLLSGSCNY PRRLEKYRFY
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269|PubMed:17535918, ECO:0000269|PubMed:18826429, ECO:0000269|PubMed:19321711, ECO:0000269|PubMed:23935008}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269|PubMed:17535918}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754450.0HG975445.1 Solanum pennellii chromosome ch06, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016503267.10.0PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
SwissprotQ9C8N51e-162STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBLA0A1S4CPT40.0A0A1S4CPT4_TOBAC; protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
STRINGXP_009624046.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA47542441
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G34370.21e-155C2H2 family protein
Publications ? help Back to Top
  1. Kobayashi Y, et al.
    Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions.
    Plant Physiol., 2013. 163(1): p. 180-92
    [PMID:23839867]
  2. Yokosho K,Yamaji N,Ma JF
    Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench).
    Plant Cell Physiol., 2014. 55(12): p. 2077-91
    [PMID:25273892]
  3. Geng X, et al.
    LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis.
    Plant J., 2017. 90(3): p. 491-504
    [PMID:28181322]
  4. Balzergue C, et al.
    Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation.
    Nat Commun, 2017. 8: p. 15300
    [PMID:28504266]
  5. Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A
    Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation.
    Front Plant Sci, 2017. 8: p. 822
    [PMID:28567051]
  6. Jiang F, et al.
    Identification and characterization of suppressor mutants of stop1.
    BMC Plant Biol., 2017. 17(1): p. 128
    [PMID:28738784]
  7. Daspute AA, et al.
    Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
    Front Plant Sci, 2017. 8: p. 1358
    [PMID:28848571]
  8. Sharma A,Wai CM,Ming R,Yu Q
    Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis.
    Genome Biol Evol, 2017. 9(9): p. 2170-2190
    [PMID:28922793]
  9. Zhang Y, et al.
    The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 118
    [PMID:29491872]